Conserved Protein Domain Family
RE_TdeIII

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pfam09520: RE_TdeIII 
Type II restriction endonuclease, TdeIII
This family includes many TdeIII restriction endonucleases that recognize and cleave at GGNCC sites. TdeIII cleave unmethylated double-stranded DNA.
Statistics
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PSSM-Id: 401463
View PSSM: pfam09520
Aligned: 19 rows
Threshold Bit Score: 199.815
Threshold Setting Gi: 268314504
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015424072       5 SADKTQKISEVVIKILYRRF-----------EEFPSDLSRnr------nAPFHKAFLQAfydkmeryqinnyELIGLSSW 67  Candidatus ...
WP_013885617       4 eNRVKEKIAIEVIKVLISRF-----------DSFPEDASNir------nAPFHDAFLNAfadkldgkvpdtpFFISLASW 66  Flexistipes...
ABK77459           8 RNTLRSEVNAWIEDFLRQKL-----------PAVLRKNNAnr-----grMPFHEALLPN-------------AVMSGFKT 58  Cenarchaeum...
BAF59305           7 PGDIEQKLKEYLAGYFHKRLiplvdkavntsKSFLDDEARrevdpegkkQPFLEAVFPP-------------EAILIKRL 73  Pelotomacul...
jgi:Osc7112_5428  17 EVFIENLVNEYRGRLIPKLDi---------pAAYLSGQSSte-----qsELLQTAIVPS-------------ELLRINEF 69  Oscillatori...
WP_004079706       8 KNAIQTVIKDLMDKIMDKVLd---------sDPFVKEEHHl-------kKPLYAALVPD-------------EIFKGSHF 58  Methanoplan...
AHJ29740           8 SKAIKDVISEMMERVMERVLi---------tDPFIKENHRs-------sKPMYAALVPD-------------EIFKGSHF 58  Nodularia s...
jgi:Cri9333_3879   8 KIAIQSVIKEMMDQVMERVLi---------iDPFISEKHRs-------sKPLYAALVPD-------------EIFKGSHF 58  Crinalium e...
WP_012745161       6 KERVRQHVKAVMERLIAKRTv---------eEPFSAKEIEe-------kNPFGYLLVPI-------------EVWKGSKM 56  Geobacillus...
CDM70051           6 KSKIEEHLREVMNRIIEKRTi---------yEPFNEDEIKr-------kNPFGYRLVPI-------------EVWKGSKF 56  Clostridium...
WP_015424072      68 LHGLNTTLGQVFFEKVAHILSGGEKREFTSARSGALYITEEQQKAIMDIM------TDLSNRNKKPDLE---RE-LQAIP 137 Candidatus ...
WP_013885617      67 LHGLNTTLGQTFFENVAQILSDGEKREYTSKKLGNLTITKNHREKISEIA------ADLSTSTELPDLE---RE-NKLLL 136 Flexistipes...
ABK77459          59 ERSFSTSLGK-LFERCSVIIARECFSHVQNQHVVHGMIPGNTKNAMDTLI------DRLDQSQGYANYQtvvNEtIERMQ 131 Cenarchaeum...
BAF59305          74 ERPFSTKLGR-TFEEAARIIAAHYHPEAKTGCRVQGAVDAFAIARIDQMLn-----LWRENSSKKPSFPemsRQaAGVID 147 Pelotomacul...
jgi:Osc7112_5428  70 ERGFSSRLGT-TYEECAKLIALEHHQEASRSYEISGEVSIEAIHEIERQLal--feQSADKNENKPAFE---EM-IEAVL 142 Oscillatori...
WP_004079706      59 ERRFVTPFGK-VWEQLAVVAATNGMGYGTTGYRIDGMIREKRLHRIAETLnrl-ehSAKGDNKVKPDWE---KE-LAYIK 132 Methanoplan...
AHJ29740          59 ERRFVTPFGS-VWEKLAQVVALEAHGNCEMGHTINGTIGQESLRRIQEILnkl-ehS-KGKEKIKPNWE---QE-LKYIK 131 Nodularia s...
jgi:Cri9333_3879  59 ERRFVTPFGK-VWEKLAVVAGREGLGHCQMAHTICGTVKSERLRRISETLnkl-ehPPSGQSRTKPDWD---RE-LSYIL 132 Crinalium e...
WP_012745161      57 ERSFVTTLGQGIFEQLGKIIAEGTGAFAANQYDKTLTINTFRTEKIDSIIkkqrskPKKGEKRVPPDLS---KE-LDDIA 132 Geobacillus...
CDM70051          57 ERSFVTSLGQGIFEQIARIIAEGSGAIAINQYQKIIRLNSWQLERIDNILenqrkkNLKTKSKNSIKLKtisEE-LEFLR 135 Clostridium...
WP_015424072     138 KAGENDLMETQGFSADVFW-IDQN-SIEAIEMKTVKPNSGEMKSEKQKILIGRTALQNKYPDKEVHFHIGFPFDPTVded 215 Candidatus ...
WP_013885617     137 QNYDGENIKAVDFSADVFF-EDED-QVIAIEIKSVKPNSGEMKGEKQKILEGKAALQKKFPKKEIYFYIGFPFDPTVdpa 214 Flexistipes...
ABK77459         132 R--DNSAGSPVTVTSDLYL--QNNdRDIYFELKSPKPNKGQCHTMLRNSLYIHAMTRRLWPRTR--TMIGMAYNPFGd-- 203 Cenarchaeum...
BAF59305         148 E-----SKREISIQADLYV-KHSSgVSYFFEIKSPKPNKDQCLASMEKMLRLQLI----KKGEAAQTFYVMPFNPYGt-- 215 Pelotomacul...
jgi:Osc7112_5428 143 EAQKTNHLVTRSVKADLYV-LSHDgRKFLFEIKGSKPNKGQCLEVIQRLLRFHLLCGQSRPAAQ--CYYAMAYNPYGp-- 217 Oscillatori...
WP_004079706     133 K--EKGELIPVSVVCDLYVeDRNNdRKYAFELKAPLPNSDQTKVSKEKILKLHCM----EPSVIDGAYFALPYNPYGt-- 204 Methanoplan...
AHJ29740         132 A--GGGQLIPVSVVCDIFIeNKEHgTRYAFELKAPLPNSDQTKVSKEKLFKLLAM----NPTVVDYAYYALPYNPYGk-- 203 Nodularia s...
jgi:Cri9333_3879 133 E--GDGEDIPVQVVCDIYAvDKTTgEKYAFELKAPLPNSDQTKVSKEKILKLHSM----EPQKINGSYFALPYNPYGk-- 204 Crinalium e...
WP_012745161     133 R-LENEKYEIITVKSDLYI-RRPDgKEEYYSLKTVKPNLDQTAEAKKNLLLLRTG----DPNCE--AYFALPYNPAGe-- 202 Geobacillus...
CDM70051         136 K-LDTDRYQDVNVLFDLYI-KRKDgTEEYYSLKTVKPNLDQTEAAKKDILRLMTS----EKNAQ--AYFALPYNPAGe-- 205 Clostridium...
WP_015424072     216 iesPCSYNKPrflnsiiCGNDFFD---PKEVLLASELWDYLSGQkDTMEFLINIIN 268 Candidatus Cloacimonas acidaminovorans
WP_013885617     215 eekVTGYNKErflrsiiNMSKFFD---PEETLVASELWDFLSGQkNTMEQILEIIN 267 Flexistipes sinusarabici
ABK77459         204 ---GAEYNHS-------FVTGIFDm--KRQVRIGREYWDLLGGD-DTYRQLLDIFA 246 Cenarchaeum symbiosum A
BAF59305         216 ---RDAYSYT-------FAKTYLDf--ENFVLLQEEFWDGIIGPpGTFQALVDIYR 259 Pelotomaculum thermopropionicum SI
jgi:Osc7112_5428 218 --nRSDYKWS-------AARKYTPf--EQAVIMGDEFWNIIGGE-TAYEELLDIYQ 261 Oscillatoria nigro-viridis PCC 7112
WP_004079706     205 ---RENYSWS-------FPARWFDmknDEVVLIGNDFWDYIGGK-GTYEAFISAVN 249 Methanoplanus limicola
AHJ29740         204 ---KENYKWT-------FPMRWFNmyeDESVLIGDEFWELIGGE-GTYSNFIkein 248 Nodularia spumigena CCY9414
jgi:Cri9333_3879 205 ---KEDYKWS-------FPSRWFNmqqDEVVLIGNEFWDKIGGV-GTYQAFIKAVN 249 Crinalium epipsammum PCC 9333
WP_012745161     203 ---GNPYSKAgh----sIPNRLFNmddERFVLIGSALWNKIGNDeNTYEELLEIFR 251 Geobacillus sp. WCH70
CDM70051         206 ---DKSYKSIh-----sIPYKLFDmdcDNNVLIGENLWNKIGMDdNTYSELLDIFD 253 Clostridium bornimense
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