2IVF


Conserved Protein Domain Family
EB_dh

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pfam09459: EB_dh 
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Ethylbenzene dehydrogenase
Eythylbenzene dehydrogenase is a heterotrimer of three subunits that catalyzes the anaerobic degradation of hydrocarbons. The alpha subunit contains the catalytic centre as a Molybdenum cofactor-complex. This removes an electron-pair from the hydrocarbon and passes it along an electron transport system involving iron-sulphur complexes held in the beta subunit and a Haem b molecule contained in the gamma subunit. The electron-pair is then subsequently passed to an as yet unknown receiver. The enzyme is found in a variety of different bacteria.
Statistics
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PSSM-Id: 401423
View PSSM: pfam09459
Aligned: 25 rows
Threshold Bit Score: 114.431
Threshold Setting Gi: 121590462
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2IVF_C         18 APIWAGAESTTFE------MFPTPLVMVkevspflalSEGHGVIKRLDVAALHNGSMIA-LRLKWASEKH--D------- 81  Aromatoleum ar...
WP_012513382   38 ADIWNKAPSTTIQ------LSGQAIVAP---------MDLNPATKSITVKSIHNSKYIA-FLLSWSDPHP--S------- 92  Hydrogenobacul...
Q9LZQ3         52 NDDWKDIDGSEFP------LRPALDPDS----------DHEYDAGKMTVKALHDGRDIY-FLLEIDGNYA---------- 104 thale cress
WP_011697317   50 DPAWQQVRPVEVR------LKGRGSFAE--------------EEVTVTAMAAYTAESIY-FLFKWKDPTEsvvkqswkfd 108 Syntrophobacte...
WP_011697316   47 DPVWQKAKPLDIP------FAGKEKFAG--------------KKANVITQAVYTDDEIF-FLFKWKDATNsvtkgawqfd 105 Syntrophobacte...
WP_012083185   51 vVVYPQTTL----------HFNDKKANE---------LNKDAKAKVIEVAAFTDGRNIA-IVTRWPDKTKdvY------- 103 Nitratiruptor ...
Q9YCG0         52 DSFWQQMEKAEIS------LVSQNIVYP---------MTGYEDVRTLRVAAAVSSEGILaIYLEWEDPTMdvP------- 109 Aeropyrum pernix
Q8ZSR9         48 SNLWPA--PVEVP------LTSQTLVYP---------LPAATETRSIGVSAVYNGTHIA-FLLTWSDNTQdvA------- 102 Pyrobaculum ae...
jgi:Dole_0195  21 SSVWQSGKAVLETaatplaNQPSPYIKGvy------dETKIGAVKKITIKAVHNGKDIV-FYCEWESGKPn-K------- 85  Desulfococcus ...
Q5NZV0         18 ASVWNDAQAMRLP------MAPVPLVLVqdwspflakSEDHGANKSLDVAALHNGKSLA-VRLKWASEKH--D------- 81  Aromatoleum ar...
2IVF_C         82 ---KIVDLNSFVDGVGAMFPV-----------------ARGAQAVT----MGATGRPVNAWYWKANANE---PMEIVAeg 134 Aromatoleum ar...
WP_012513382   93 ---TFRVNDKFSDAVALEVPLk----------------PDNTTPIT----MGGNGKEVVILQWAAYRQYn-iTKGFADip 148 Hydrogenobacul...
Q9LZQ3        105 ---YDKGENNKCPSVALMFQIgdqatyhn--mggckegTDSCTS------KACRGFEVDIMHFSIGNAIp--GRLYGGnp 171 thale cress
WP_011697317  109 gqnwTHMKGD-EDRIALLFEIsringfatkgctvvchsPPDVPSKEwkfaTETPAEKGDLWHWKAARSN---PYHHADdg 184 Syntrophobacte...
WP_011697316  106 gekwTHLKGD-EDRISLLFEInrinnfatkgcavtchgAAGAAVKDfkfaTASAGEKGDLWHWKAARSD---PYKSADdg 181 Syntrophobacte...
WP_012083185  104 ---KGYKSDIYPDGFAVQFASda-------------skPEKLPYIG----MGSDGRPVAIYLRKAYAQGvyePNGHGDva 163 Nitratiruptor ...
Q9YCG0        110 ---QPGGIDEYPDKVAVQFPLs----------------SDSLPYIC----MGTAEQPVSIVLWSASGST----ETLIAgs 162 Aeropyrum pernix
Q8ZSR9        103 ---TPGGLDVFPDAVAVQFPVs----------------KAQLPYIC----MGTVDNPVNIIYWRAGFGA----ENLVAga 155 Pyrobaculum ae...
jgi:Dole_0195  86 ---EIGDINVFPDGVALLFPFk---------------dIDKTPINE----MGTQDYPTNAWYWRPDFEEk--PKNQVS-- 139 Desulfococcus ...
Q5NZV0         82 ---QMPDLDSFVDGAAVLFPL-----------------VEGAPAMT----MGAKGKPTNAWFWKANQKS---AMEVVA-- 132 Aromatoleum ar...
2IVF_C        135 f----------savRRMKDKAG---------------------------------------------------------- 146 Aromatoleum ar...
WP_012513382  149 kie-------pyyyTGYIYPQAkppyaypkdwnnkyaqdyvggkvpy-------------wkntrdtsviefiadgyttt 208 Hydrogenobacul...
Q9LZQ3        172 id---------ngeGNGGDRFGhlvdiyawnphcryldglgpsg-------------------ndssaqndwhgawwhss 223 thale cress
WP_011697317  185 wltladnpsgsyrtTGRRADGGgggdvnnetpdktrplymqdpsripsapgfllfeeavnipddavfkagdiipyrmpkk 264 Syntrophobacte...
WP_011697316  182 wlt------aagekTGRKDDAGgggdarnetadkskpqfmqdpskkpsapgvllaedtveitdhgkfkandtltyrmpkk 255 Syntrophobacte...
WP_012083185  164 h----------qvnEHNTNYFGkslkkfekevkklgvrpyq--------------------------rafvsegfrsmte 207 Nitratiruptor ...
Q9YCG0        163 ay---------gmsPEHREALGlhsvptsp-----------------------------------------------iel 186 Aeropyrum pernix
Q8ZSR9        156 gy---------glnPQQREALGlqatpasp-----------------------------------------------vel 179 Pyrobaculum ae...
jgi:Dole_0195 140 --------------------HGlstsl----------------------------------------------------- 146 Desulfococcus ...
Q5NZV0        133 --------------ESFTAVQRleg------------------------------------------------------- 143 Aromatoleum ar...
2IVF_C        147 -----SDLKAVAQH--RNG----EWNVILCRSMATGDGLa---KLQAGGSSKIAFAVW---SGGNAERSGRKS 202 Aromatoleum aromaticu...
WP_012513382  209 twrkhQEAKGVGVY--KNG----KWYVEIIRPFNIKGALn--pEWGPNSKTFIDFAVW---QGYAKERDSRKA 270 Hydrogenobaculum sp. ...
Q9LZQ3        224 fttlsGYVEEDSPY--TPDgkkgTYYFEFSRPLRTMDRLqqdvQFTLGSPAKMSVAFWypvDSKPWHGSGHYT 294 thale cress
WP_011697317  265 pdgsrSDVKAIGQY--ADG----GWTVMLYRKLDTGREDd--vAFNPRKEYSFAMAVF---DDSGDDHSKATR 326 Syntrophobacter fumar...
WP_011697316  256 psgsrADIKAESRY--ADG----GWTVMLSRKLDTGNDDd--vAFNTKKKYSFALALF----DDSMDYDSYDS 316 Syntrophobacter fumar...
WP_012083185  208 ikdnsANFRTDMYYvkKYH----KWGGMVVRPIKDAYAK------PTKNEFAVAIAVW---DGKELQRDGLKR 267 Nitratiruptor sp. SB1...
Q9YCG0        187 vppeaQVWGSNAVY--KDG----KWMVVLYRPTGSIHELv--pTLEPGSETSVAFAVW---QGSKAEVGGKKS 248 Aeropyrum pernix
Q8ZSR9        180 lpasaQVINATAAY--KDG----KWYVVIIRPLGSVHPL----MASLAEGFSAAFATW---DGAKGEIGGLKA 239 Pyrobaculum aerophilum
jgi:Dole_0195 147 -ytekSSISSYSRW--ANG----KWCVVMARPMKATQPGeetvDLMPGKAIGFGIAVW---EGSNGERGGIKA 209 Desulfococcus oleovor...
Q5NZV0        144 --katSDLKTVAQH--QNG----EWQVIFRRSLANRDGLv---QLPIGGNGKIAFALW---NGGNKERSGRKS 202 Aromatoleum aromaticu...
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