Conserved Protein Domain Family
MRC1

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pfam09444: MRC1 
MRC1-like domain
This putative domain is found to be the most conserved region in mediator of replication checkpoint protein 1.
Statistics
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PSSM-Id: 401412
View PSSM: pfam09444
Aligned: 79 rows
Threshold Bit Score: 46.0092
Threshold Setting Gi: 164660646
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
GAC71561     1436 DKKRKSAFIEGEAEESEDedlgeqkrgDGGGLKGVfadengsdsgKDEDEDDEEdeDAeDLQELVDNERdIDE--AQKDE 1513 Moesziomyces ...
XP_001837399  882 RKLDKSEFVEDEADESDDd----------AGFWGRpk------kdDDEEMENDEd-LDkTLETLVDDQEmDDQ--TLAEE 942  Coprinopsis c...
XP_007329579 1075 gkmvRKEWLAEEAEESDEd--------EAVGFGFIkr------ksREDDEEGENgdLDaTLTELVDDEKmDED--TAGAD 1138 Agaricus bisp...
EPT02727     1060 gKTKRSEFIEGEAEESDDd--------EMRGFGLRk--------rVEDEDEDDEa-QDqTLQELVDDQDmDEN--TLAED 1120 Fomitopsis pi...
XP_002475465 1079 rRLQKSEFIEGEAEESDDd--------AMMGFGPRn--------kVDEDEEDDEs-QDqTLTELVDDAAmDAE--TLAEH 1139 Postia placen...
EMD40666       63 kalRKSEFIEGEAEESDDd--------ALAGFGIRkq-------pEDDEESGGEd-QDqLLAELVDDTAlDEK--ALAAD 124  Gelatoporia s...
XP_009265877  746 krpidpRYFEAQAEISDEd--------NLVGLI------------SDDEEDDER--NNrQLDELVNDDRvAREtrDKQDK 803  Wallemia icht...
EIM21111      746 gapidprFFEAQAEESDEe--------NLMGLI------------SEDEEEDDG--VDrHLEELVNDERvAKElrEKQDK 803  Wallemia mell...
EPB87024      637 gprEKLEYLEEEAEEEDD---------EFFGAGGS----------DGETGENLD--EFeKDDLLVEDNNeHID----EAA 691  Mucor circine...
XP_006675518  800 siKKSSKFVETEAEVEDD---------EFMHVGGV----------DGEDDPDID---QyEQDMLGDSDIeDMQ----QEA 853  Batrachochytr...
GAC71561     1514 VARARFREDMEARDREDLEIHQKAIQGGYRnRRGrg-agLNGIeGFLddDADEEElqrrAaLGLHMSSSAWKKRKLLDGT 1592 Moesziomyces ...
XP_001837399  943 RVREKFKEQEQQEDEKLEKIAHNVVEGEFRkRKkdg------gfNLSdeSDDDDEd-----ENRKARRRLRRQQK----N 1007 Coprinopsis c...
XP_007329579 1139 RVMEKHQELLEQDDEAALKFHQGVVQGELRkKRKnrf---------gleDSDDEEe-----EDDRARRIRRKMKE--KVE 1202 Agaricus bisp...
EPT02727     1121 AVLEKHREQLEQDDQEVEKLHQDAIQGKLRmARrnr------gvGFEddDSDEEDd-----DAARARRRMQRQKR--NVQ 1187 Fomitopsis pi...
XP_002475465 1140 AVIEKHREHQQIDDEANEKLQKDVVAGNWKtKRrdr------giGFEdsDSEDDDd-----DDAKARRRKMSKKR--RIE 1206 Postia placen...
EMD40666      125 AVLEKVREHEEEDDRQLEKLHRDAVEGKLRlRRrdh------gvGFEdeDSDEDEd-----DRIR-RQRAMRKKR--KLD 190  Gelatoporia s...
XP_009265877  804 LATEKYQEQLKEDDELDKKVAQNAADGRYRyRRRhrnedGLEMsS------DDDDiefmKaQEQLATRLAKRRRK--QAG 875  Wallemia icht...
EIM21111      804 LATEKYQEQRQQDDELDKKVAQNAVDGRYRyRRRhrtedGLDMsS------DDDDiefmKaQEQLAARMEKKRRK--HAG 875  Wallemia mell...
EPB87024      692 LREAFNLQDKETDSNMIQRLITDITSGNLR-KQKaalesGLMLdDIDlyDEEDNDlvaiRrLQAARRRRLLKKKG----- 765  Mucor circine...
XP_006675518  854 IANLHLKQLLEKDKSEFEALLNDVTSGNLRkRGRrndptGKGL-DMHdsDEENEEl-----LRRIRDQFKSKTNGNDNDD 927  Batrachochytr...
GAC71561     1593 QdGMDALAAHDEAKAFVH 1610 Moesziomyces antarcticus T-34
XP_001837399 1008 ReDVLALTLNPETHAFAQ 1025 Coprinopsis cinerea okayama7#130
XP_007329579 1203 RgDIQELAANEKTAAFAn 1220 Agaricus bisporus var. burnettii JB137-S8
EPT02727     1188 GdSLDEIAKDPASAPFVK 1205 Fomitopsis pinicola FP-58527 SS1
XP_002475465 1207 DdSLEQLAKNPETLAFVQ 1224 Postia placenta Mad-698-R
EMD40666      191 DdRLEELAKHQDTLPFVQ 208  Gelatoporia subvermispora B
XP_009265877  876 EePMERYARNPRTAAFVA 893  Wallemia ichthyophaga EXF-994
EIM21111      876 EePMDVIARNPRTAAFAA 893  Wallemia mellicola CBS 633.66
EPB87024      766 GdILENLLSDPKTAAFAK 783  Mucor circinelloides f. circinelloides 1006PhL
XP_006675518  928 LvSLEKLAQDPKTASFAK 945  Batrachochytrium dendrobatidis JAM81
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