3WCY,3SE4,2KZ1,4DOH,3G9V,1A21,3LQM


Conserved Protein Domain Family
Interfer-bind

?
pfam09294: Interfer-bind 
Click on image for an interactive view with Cn3D
Interferon-alpha/beta receptor, fibronectin type III
Members of this family adopt a secondary structure consisting of seven beta-strands arranged in an immunoglobulin-like beta-sandwich, in a Greek-key topology. They are required for binding to interferon-alpha.
Statistics
?
PSSM-Id: 401291
View PSSM: pfam09294
Aligned: 35 rows
Threshold Bit Score: 66.6062
Threshold Setting Gi: 28475295
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3WCY_A       100 AHMSPPEVRL-EAEDKAILVHISPP--------GQDGNMWALEKpSFSYTIRIWQKS--SS----DKKTINSTYYVEKIP 164 house mouse
Q7ZT35       115 TVLGPPEVDV-TVSGCGNCLLLQVNrsp--trgLKRLRILDYYQ---ELVVLVRRTR--DGa---QFNLTLGTKDDMLIS 183 spotted green p...
O35664       132 APLEPPEFEI-VGFTDHINVTMEFPpvts-kiiQEKMKTTPFVI-KEQIGDSVRKKH--EP----KVNNVTGNFTF-VLR 201 house mouse
2KZ1_B       105 MSFEPPEFEI-VGFTNHINVMVKFPs-----------IVEEELQfDLSLVIEEQSEGivKKhkpeIKGNMSGNFTY-IID 171 human
NP_001038744 132 TNFSPPQIKVtVAGGQTIKVQIKPPrtplrghnGNRIRVTKLHK--LTFRIFLMHND--VEe---EVHETDSCSKELVIE 204 zebrafish
CAD67770     108 aRISPPVLKL-KVSQQKVVVQVEPPr----------LHIRKMHS-SLQFKIYLTHPS--GE----EELFLVDPRSRKLTL 169 spotted green p...
Q80XF5       125 TKLDPPVVTI-TRVNASLRVLLRPPelpnrnqsGKNASMETYYG--LVYRVFTINNS--LEk---EQKAYEGTQRAVEIE 196 house mouse
3G9V_A       106 TKIDPPVMNI-TQVNGSLLVILHAPnlpyryqkEKNVSIEDYYE--LLYRVFIINNS--LEk---EQKVYEGAHRAVEIE 177 human
Q04790       330 TIIFPPVISVkSVTDDSLHVSVGASe------eSENMSVNQLYP--LIYEVIFWENT--SNa---ERKVLEKRTNF-IFP 395 cattle
Q764M8       330 TILFPPVINMkPINDASLRVGIGAPk------eSEDKSVNQLYP--LIYEVIFRENT--SDt---ERDVLEKRTDF-TFS 395 pig
3WCY_A       165 ELLPETTYCLEVKA--IHPSLKKHSNYSTVQCISTT 198 house mouse
Q7ZT35       184 YLQPGVEYCVSVSV---KMLFRSSSASSRPRCAFTS 216 spotted green pufferfish
O35664       202 DLLPKTNYCVSLYF------DDDPAIKSPLKCIVLQ 231 house mouse
2KZ1_B       172 KLIPNTNYCVSVYL---EHSDEQAVIKSPLKCTLLP 204 human
NP_001038744 205 ALRPKTTYCLQALS--VTPRSGRISSRSPRTCITTh 238 zebrafish
CAD67770     170 HLRHRQRYCVQAQT--QILLQAKSSARSPPTCVSTl 203 spotted green pufferfish
Q80XF5       197 GLIPHSSYCVVAEM--YQPMFDRRSPRSKERCVHIP 230 house mouse
3G9V_A       178 ALTPHSSYCVVAEI--YQPMLDRRSQRSEERCVEIP 211 human
Q04790       396 DLKPLTVYCVKARAliENDRRNKGSSFSDTVCEKTK 431 cattle
Q764M8       396 NLKPLTVYCVKARAliENDRWNRSSVFSDTVCEKTK 431 pig
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap