5FUR,1TBA


Conserved Protein Domain Family
TBP-binding

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pfam09247: TBP-binding 
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TATA box-binding protein binding
Members of this family adopt a structure consisting of three alpha helices and a beta-hairpin. They bind to TATA box-binding protein (TBP), inhibiting TBP interaction with the TATA element, thereby resulting in shutting down of gene transcription.
Statistics
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PSSM-Id: 370383
View PSSM: pfam09247
Aligned: 23 rows
Threshold Bit Score: 60.683
Threshold Setting Gi: 159163051
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5FUR_G         28 EDSAGG--GPFSLAGFLFGNINGAGQLEGEsV---------LDDECKKHLAGLGAL-GLGSLITELTA 83  
EEB18871        3 NNIS----SPLSLAGFLFGNIDESGQLDTD-L---------FDNEAKKYLNALTRL-GFDSLVDEIIG 55   human body louse
EEC16643       12 SDEDGE--PDLVLTGFLFGNIDKHGRLEND-F---------LDPESKRNLHQLNHL-GIGRMWEEITG 66   black-legged tick
XP_002609160   28 DEDDRE--PPLSLTGFLFGNIDQKGQLEDDdI---------LDQESKRHLNQLNSLgGFGSLVQEITA 84   Florida lancelet
XP_009028572    6 SESND---QTAVLTGFLFGNIDESGNLEED-F---------LDEESRRRIGFLAGF-GIESFVKEIAE 59   Helobdella robusta
1_pfamImport    2 SDDEET--GKFELTSFLFGNIDERGELEDD-I---------LDNESKRHLSSLARL-GFGSFIKEIVN 56  
XP_002070787    3 SDDD----LGMDLTGILFGNIDSDGRLLDDdDgn-----gkFDAEFRENLGSLSKL-GLNSMLNEVIT 60   Drosophila willistoni
XP_003241670    5 SSSEAQq-GDFDLTSFMFGNIDESGQLEDDdL---------LDKDTKKYLASLSKL-GFSSMVSEVID 61   pea aphid
EDW55129        8 SDDEGSigNGLDLTGILFGNIDSEGRLLQDdDgegr-ggtgFDAELRENIGSLSKL-GLDSMLLEVID 73   Drosophila sechellia
1TBA_A          1 -EGSIG--NGLDLTGILFGNIDSEGRLLQD-DdgegrggtgFDAELRENIGSLSKL-GLDSMLLEVID 63  
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