1V0D


Conserved Protein Domain Family
DFF40

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pfam09230: DFF40 
DNA fragmentation factor 40 kDa
Members of this family of eukaryotic apoptotic proteins induce DNA fragmentation and chromatin condensation during apoptosis.
Statistics
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PSSM-Id: 401245
View PSSM: pfam09230
Aligned: 29 rows
Threshold Bit Score: 305.733
Threshold Setting Gi: 270012197
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1V0D_A              103 IQAARQQLSdEQAPLRQKLLADLLHHVSQ------NITA---ETREQDPSWFEGLESRF-RNKSGYLRYSCESRIRGYLR 172
EEC08309             48 lasrsnevvaaLEPYKSQLIEQMLGNIESlevpehVLLA---DNKDQDPKWFEG-EKRA-TSKRKVMRERAKTRIKGYFY 122 black-le...
Q29KJ1              120 PEKFRRMIS-DYEHQKQRLVLDNSKAH-----------L---SLKDEHVEWFEGGEERF-HSKEEAMAVRAQTRVRGYYY 183 Drosophi...
XP_002057690        148 PDKFRRMIT-EYEQQKQRRALDNTKAH-----------L---SLKAEHLEWFEGSEERF-QSKEEAMAMRAQTRVRGYYY 211 Drosophi...
WGS:AAQB:GK15294-PA 149 PDKFRRMIT-QYELQKQRRMLDNTKAH-----------L---SLREEHMEWFKGGEERF-HSKEEAMSMRAQTRVRGYYY 212 Drosophi...
Q17BG6              110 GTLVQEFVS-NNQGEIAKLLHNAQRSQDE------QTLK---SHRSEHAEWFEGIDEKSgQTKEEVMQRRGQDRIRGYFY 179 yellow f...
ETN62080            113 GELAKQFVS-NNQPEISKILIDAQRGRDD------LIRR---SSRNEHEQWFEGIDDRAvKTKEEVMKRRGQDRVRGYFY 182 Anophele...
XP_008179151         96 sikIKSFMD-ENIKEKIRILSSVLDVDDE------SKKKkisSLRLRDPDWFQGLETRA-RTKEEFMFKRCQERIRSYMY 167 pea aphid
EDS28031            111 GSLAKQFVS-NNQTQIARMLEEAQRAQDE------RTAK---SRRSEHAEWFEGFDSRAgQTKEEIMQRRGQDRIRGYFY 180 southern...
XP_318738           113 GELAQQFVS-NNQPEISKILFNAQRGRDD------LIQR---SAREEHAEWFEG-KKKAaVTKEEVMKRRGQDRIRGYFY 181 Anophele...
1V0D_A              173 EVSAYTSMVd----EA-AQEEYLRVLGSMCQKLKSVQYNGSYFDRG---------------------------------- 213
EEC08309            123 KSKEDLQKCv----SEnGKQCLSQLFEEFSALLRAGDHNGHYFVRG---------------------------------- 164 black-le...
Q29KJ1              184 KAKEELTRNplyrqNPkARQVINSVLEQFRYLLIGCDYFSMMFNRKceqkhdflqqhrqqtgdeepda------------ 251 Drosophi...
XP_002057690        212 KTKEELTRNqlyrqNAkARQVINSVLDQFRYLLIGCDYFSMIFNRKcqlkhemlqqqvgveqpdagn------------- 278 Drosophi...
WGS:AAQB:GK15294-PA 213 KTKEELTRNplyrqNAkARQVINSVLEQFRYLLIGCDYFSMMFDRKcqqkheflshqlqqeeeetdga------------ 280 Drosophi...
Q17BG6              180 KTKDELTKCaiyrqNAmAKELIDEMLDLFRQLLSGFDFFSCIFDRShsrrltegavsnlvltteehkrnqgggd------ 253 yellow f...
ETN62080            183 KAKDELTKCamyraNPvARELIDEMIELFRQLLAGFDYFSCMFDRTcqrrmtvpeetigdakddvadetd---------- 252 Anophele...
XP_008179151        168 KTKSDMIKSdfyikQTkCRKYLDEVFKQFSELLTKNKHHGYYFDRS---------------------------------- 213 pea aphid
EDS28031            181 KTKDELTKCaiyrgNVmAKELIDEMLELFRHLLIGFDYFSAIFDRShparlpdnaevsdlvvgsgertvaaaaaaspdgq 260 southern...
XP_318738           182 KTKDELTKCamyrgSPmARELIDEMLELFRQLLVGFDYFSCMFDRScqrrmelkpdtedggdepdaq------------- 248 Anophele...
1V0D_A              214 -----------------------------AEASSRLCTPEGWFSCQGPF--DLESCLS----KHSINPYGNRESRILFST 258
EEC08309            165 -------------------------------EKEALCCEKGQFLCQGTF--SKPSCDSr---VHRINPYGSREQLVCFST 208 black-le...
Q29KJ1              252 -------gslpskrlrqlikeytkqhsilDDWSVSLCTDLGDFYCQGAYsdNGNCCSL----QHTINPYASRENLILFQV 320 Drosophi...
XP_002057690        279 ---------vpnkrlrqiikdytsrhailDEWSVSLCTDLGDFYCQGAYsdNGNNCSL----RHTINPYASRENLILFQV 345 Drosophi...
WGS:AAQB:GK15294-PA 281 --------asvpkrlrqlikdytkrnnilDKWSVSLCSNLGDFYCQGSYsdNGNCCSR----QHSINPYASRENLILFQV 348 Drosophi...
Q17BG6              254 --evdaprimpkrmklaiekslqndgnaiEKYRVALCNDRGDFSCMGLW--NETTCKYe---AHIINPYVSRENMILFQV 326 yellow f...
ETN62080            253 ------akrippkrlkllvqrslgsscriDQYNAALCSVRGDFRCMGLW--DDVRCRYd---SHRINPYANREALILFQV 321 Anophele...
XP_008179151        214 -----------------------------NTNG--LCDEIGTFKCEGAW--NQSVCSYergtGHKINPYQSRESRIIFST 260 pea aphid
EDS28031            261 edevdaqrivpkrmklaiketlekdgnaiERYRVALCNSRGEFRCMGLW--NERKCKYg---AHVINPYASRENMILFQV 335 southern...
XP_318738           249 --------rippkrlkllvqsslgrgcriEPYNVALCSERGDFRCMGVW--KDERCRYa---SHRINPYASRENLILFQV 315 Anophele...
1V0D_A              259 WNLDHIIEKKRTVVPTLAEAI------------------QDGREVNWEYFYSLLFTAENLKLVHIACHKKTTH------K 314
EEC08309            209 WNLDHRVERSRSILPAIGKAIe----------------eANGRILNARYFYKLLFTTDNLKLVHPVCHIKSEHg-----G 267 black-le...
Q29KJ1              321 WNLDHQIELSRTILPAMVANVeelvtkpq---lkcsfhnKRVVDISVLEYFLEIFSLKNLKLVHVVCHEKVQRsnrsngR 397 Drosophi...
XP_002057690        346 WNLDHQIELCRSILPALVANVkelvsqpq---kkcalhnKRIVDISVLEYFLEIFSLKNLKLVHIVCHEKVQRtnhsngR 422 Drosophi...
WGS:AAQB:GK15294-PA 349 WNLDHQIELCRSILPSLVANVeklitqpq---lkctlhhKRVIDISVLEYFLEIFSLKNLKLVHITCHEKTQRtnnsngR 425 Drosophi...
Q17BG6              327 WNLDHQVEIRRTVLPSIVENLkrvienea--daickihnRRGKKLSVITYFIELFTLGNLKLVHIVCHDKSIHdmiskgS 404 yellow f...
ETN62080            322 WNLDHQIEISRTVLPSILTNIgrmvsaege-vaickrhkRKGKQLSVITYFLELFTLHNLKLVHIVCHDKGAHdlvsrgT 400 Anophele...
XP_008179151        261 WNLDHWVERSRTIIPALFEASkm--------------asEVHRSINMNYFYELLFTTVNLKLVHIVCHDKGQHi-----S 321 pea aphid
EDS28031            336 WNLDHQVEISRSVLPSIVQNVarvvakea--davcrvhnRRGKKLSVITYFIELFTLGNLKLVHIVCHDKSIHdmisrgA 413 southern...
XP_318738           316 WNLDHQVEISRSVLPSILDNVermvssadggapmcklhrRKGKNLSVITYFLELFTLSNLKLVHIVCHDKTVHelisngT 395 Anophele...
1V0D_A              315 LECDRSRIYR 324
EEC08309            268 FKCERAHWYv 277 black-legged tick
Q29KJ1              398 LLCPDCHEYR 407 Drosophila pseudoobscura
XP_002057690        423 LLCGDCHEYR 432 Drosophila virilis
WGS:AAQB:GK15294-PA 426 LVCSECHEYC 435 Drosophila willistoni
Q17BG6              405 IICDKCAEYK 414 yellow fever mosquito
ETN62080            401 IICDRCEEYQ 410 Anopheles darlingi
XP_008179151        322 AKCDPnlylq 331 pea aphid
EDS28031            414 IICEKCAEYK 423 southern house mosquito
XP_318738           396 IICDRCEEYK 405 Anopheles gambiae str. PEST
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