1KCF


Conserved Protein Domain Family
Ydc2-catalyt

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pfam09159: Ydc2-catalyt 
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Mitochondrial resolvase Ydc2 / RNA splicing MRS1
Members of this family adopt a secondary structure consisting of two beta sheets and one alpha helix, arranged as a beta-alpha-beta motif. Each beta sheet has five strands, arranged in a 32145 order, with the second strand being antiparallel to the rest. Mitochondrial resolvase Ydc2 is capable of resolving Holliday junctions and cleaves DNA after 5'-CT-3' and 5'-TT-3' sequences. This family also contains the mitochondrial RNA-splicing protein MRS1 which is involved in the excision of group I introns.
Statistics
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PSSM-Id: 401193
View PSSM: pfam09159
Aligned: 47 rows
Threshold Bit Score: 144.818
Threshold Setting Gi: 151943180
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KCF_A        42 VLGIDLGIKNFSYCFASQ-----------------NEDSKV--------IIHNWS----VENLT---------------- 76  fission yeast
XP_002498978  70 ITAIDAGVSNFAYSVFKWy----------------KGDELP--------TLVDWN----KINLC---------------- 105 Zygosaccharomyc...
P41905        11 VPAIDLYCRKANFKTLKFlsmilcskkewydntkaPVRNFLvsrcavfeQLRNRLvdegKVNLFgvfltndsfsfckmtv 90  Saccharomyces p...
EDZ71439      11 IPAIDLYCRKANFKTLKSlsmilgskkewydtkktPLRNFLvsrcgifeQLRGRLvedgKVNLFsvfltndsfsfckmtv 90  Saccharomyces c...
EDV09470      11 IPAIDLYCRKANFKTLKSlsmilgskkewydtkktPLRNFLvsrcgifeQLRGRLvedgKVNLFsvfltndsfsyckmtv 90  Saccharomyces c...
P07266        11 IPAIDLYCRKANFKTLKSlsmilgskkewydtkkaPLRTFLvsrcgifeQLRGRLvedgKVNLFsvfltndsfsfckmtv 90  Saccharomyces c...
EDN61515      11 IPAIDLYCRKANFKTLKSlsmilgskkewydtkkaPLRTFLvsrcgifeQLRGRLvedgKVNLFsvfltndsfsfckmtv 90  Saccharomyces c...
Q03702        69 ILSMDAGVSNFAFSKMQLl----------------NNDPLP--------KVLDWQ----KINLE---------------- 104 Saccharomyces c...
Q6FL87        62 VTAIDAGVSNFAYCSLQL-----------------RKDRKP--------LLVGWE----KFQLEs--------------- 97  [Candida] glabrata
EDO15813      67 IMGIDAGVSNFSLAKFCWp----------------TDSRLP--------SLTGWD----KFQLEq--------------- 103 Vanderwaltozyma...
1KCF_A        77 -----------------EKNGLDIQWTEDFQPSSMADLSIQLFNTLH-EKFN-PHVILMERQRYRS-GIATIPEWTLRVN 136 fission yeast
XP_002498978 106 -----------------QRFLGKHRLKMSLDPMDTWKVGHGLLDMLT-SELAiSDLYVLEKQRMRSlSSKNVIESVLLSN 167 Zygosaccharomyc...
P41905        91 ddkfdtslvdwqkipfdYSFATERRQHISLLPPDTLFATEKIISLLG-VSPNmANLVSIERQRSDLmDFSC----KLQSN 165 Saccharomyces p...
EDZ71439      91 ddkfntslvdwqkipfdSTFATDRRQNISLLPVDTLFATEKIISILG-VSPNmTNLVSIERERSDLvDFNC----KLQSN 165 Saccharomyces c...
EDV09470      91 ddkfntslvdwqkipfdSTFATDRRQNISLLPVDTLFATEKIISILG-VSPNmTNLVSIERERSDLvDFNC----KLQSN 165 Saccharomyces c...
P07266        91 ddkfntslvdwqkipfdSTFATDRRQNISLLPVDTLFATEKIISILG-VSPNmTNLVSIERERSDLvDFNC----KLQSN 165 Saccharomyces c...
EDN61515      91 ddkfntslvdwqkipfdSTFATDRRQNISLLPVDTLFATEKIISILG-VSPNmTNLVSIERERSDLvDFNC----KLQSN 165 Saccharomyces c...
Q03702       105 ------------------EKFFQNLKKLSLNPAETSELVFNLTEYLF-ESMPiPDMFTIERQRTRTmSSRHILDPILKVN 165 Saccharomyces c...
Q6FL87        98 ----------------kFVDGHMDGDKLALNPENFSRLATKLSQYLLaLPYA-TQLYAIERQRARSmSSKFVLEPVLRSN 160 [Candida] glabrata
EDO15813     104 -----------------KFLSDKEPAVLSLHPHEITTVCGQLVQTLD-QEFGiPNLYAIERQRARTmSSKSVLEPVLKSN 165 Vanderwaltozyma...
1KCF_A       137 MLESMLYALHYAEKRNSIEQKIQYp---FLLSLSPKSTYSYWA---------------------------SVLNTKASFS 186 fission yeast
XP_002498978 168 VMEHILFSNLRNKQIHGNLNTDY-----VVHSSSPQKMAQYWCdlkslktlynrftqstglqpqkdlpfnDADNFHAAKT 242 Zygosaccharomyc...
P41905       166 ILEHLLYAKCQGVQVTSTNEEARL----LAAICNPEFIDAFWCeltpiraslke-----npsisvpqeyqIYDPVIRATI 236 Saccharomyces p...
EDZ71439     166 ILEHLLYAKCQGVYVTSTNEKVRL----LAAVCNPEFIDTFWCeltpirvslke-----npsisvpreyqIYDPVVRATI 236 Saccharomyces c...
EDV09470     166 ILEHLLYAKCQGVYVTSTNEKARL----LAAVCNPEFIDTFWCeltpirvslke-----npsisvpreyqIYDPVVRATI 236 Saccharomyces c...
P07266       166 ILEHLLYAKCQGVYVTSTNEKARL----LAAVCNPEFIDTFWCeltpirvslke-----npsisvpreyqMYDPVVRATI 236 Saccharomyces c...
EDN61515     166 ILEHLLYAKCQGVYVTPTNEKARL----LAAVCNPEFIDTFWCeltpirvslke-----npsisvpreyqMYDPVVRATI 236 Saccharomyces c...
Q03702       166 ILEQILFSNLENKMKYTNKIPNTSklryMVCSSDPHRMTSYWCipre-------------------etptSSKKLKSNKH 226 Saccharomyces c...
Q6FL87       161 ILEYLLFSTLANAKETGRGTKDY-----EIISSDPQRMVNYWVtvgs--------------------sntKYQELILDKN 215 [Candida] glabrata
EDO15813     166 ILEHVLFATLFNRRQYSATLPRMEy---NVESSDPGRMTSYWMelpsmqgik----------aefqdnlkLEQTKLSGKN 232 Vanderwaltozyma...
1KCF_A       187 KKKSRVQMVKELIDGQKi------------------------lFEN------------EEALYKWNNGSRVEF------- 223 fission yeast
XP_002498978 243 SKTIRINLVKTILKNAI----------------------------Apqg------ykkCNLTPHWRSNVEQQLnsqkrfk 288 Zygosaccharomyc...
P41905       237 KEVVAKRLLRSAFDNDIdplmrlrldkgwkfkfptlssttdldFSLkdclsldtrrdaYDMTEVFLATMASSKtlrtysn 316 Saccharomyces p...
EDZ71439     237 KEVVTKRLLRSAFDNDIdplmclhldkdwkfkfpilssttglnFSLkdclsldtgkdaSDMTEVFLATMESSKvlrtysn 316 Saccharomyces c...
EDV09470     237 KEVVTKRLLRSAFDNDIdplmclhldkdwkfkfpilssttglnFSLkdclsldtgkdaSDMTEVFLATMESSKvlrtysn 316 Saccharomyces c...
P07266       237 KEVVTKRLLRSAFDNDIdplmclhldkgwklkfpilssttglnFSLkdclsldtgkdaSDMTEVFLATMESSKvlrtysn 316 Saccharomyces c...
EDN61515     237 KEVVTKRLLRSAFDNDIdplmclhldkgwklkfpilssttglnFSLkdclsldtgkdaSDMTEVFLATMESSKvlrtysn 316 Saccharomyces c...
Q03702       227 SKDSRIKLVKKILSTSIl------------------------eGNStss------tklVEFIGVWNNRIRNALtkkksfk 276 Saccharomyces c...
Q6FL87       216 SKKYRIALVSDILCNSVhddw----------------------------------dfgVELTSIWRRRIAKAQnkktsdl 261 [Candida] glabrata
EDO15813     233 SKLLRINIVKRIIDAAVf------------------------nKDVperlidlepklrNRLLDRITTDTNDYKlfdvlql 288 Vanderwaltozyma...
1KCF_A       224 ----------------KKDDMADSALIA-SGWMRWQAQLKHY 248 fission yeast
XP_002498978 289 lldc--igsgpelgtrKDDDLADSFLHG-LAWMHWSKTYEGA 327 Zygosaccharomyces rouxii
P41905       317 lvdi-vmkdngrfdsgILKQFNDYVKQEkLNLQNFQAGSSEF 357 Saccharomyces paradoxus
EDZ71439     317 ladi-vmkdngrldsgVLKQFNDYVKQEkLNLQHFQAGSSKF 357 Saccharomyces cerevisiae AWRI1631
EDV09470     317 lvdi-vmkdngrldsgVLKQFNDYVKQEkLNLQHFQAGSSKF 357 Saccharomyces cerevisiae RM11-1a
P07266       317 lvdi-vmkdngrldsgVLKQFNDYVKQEkLNLQHFQAGSSKF 357 Saccharomyces cerevisiae S288C
EDN61515     317 ladi-vmkdngrldsgVLKQFNDYVKQEkLNLQHFQAGSSKF 357 Saccharomyces cerevisiae YJM789
Q03702       277 lcdi--leiqdnsgvrKDDDLADSFLHC-LSWMEWLKNYESI 315 Saccharomyces cerevisiae S288C
Q6FL87       262 klytliensdtnlgtkKDDDLADSFLHA-LMWSKWLNNYETL 302 [Candida] glabrata
EDO15813     289 s--------peqagakKDDDLADSFLHG-LAWVQWLRTYNDL 321 Vanderwaltozyma polyspora DSM 70294
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