1R75


Conserved Protein Domain Family
DUF1935

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pfam09149: DUF1935 
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Domain of unknown function (DUF1935)
Members of this family are found in various bacterial and eukaryotic hypothetical proteins, as well as in the cysteine protease calpain. Their exact function has not, as yet, been defined.
Statistics
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PSSM-Id: 401186
Aligned: 63 rows
Threshold Bit Score: 73.8229
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1R75_A         24 NGKPTVKGTKTYPMFSN------------ILYRIADTEArrWAFYNDSKELIIHVAVLFDYDSQIV----PLGDTTAFRi 87   Leishmania major
XP_001567058  153 YCGPSVKG-IVSAVIDEg-----------VLYRILTDGg-dWAFYNDTRYYTVQVRYRIAAGSTVT----PGNSVTVTG- 214 
Q4Q6M3        194 FGQPSVSG-LVTRVFSEg-----------MLYKIKTPKg-eYHFYNDTLQEVMVVRVQCHLRGNEK----INERAMLSPv 256  Leishmania major
Q4QCS6         27 NWGPSIDG-EATPCFKGg-----------FLYRIIDSKKkvWALYNDTFVYEMHATFIFGPVSNME----PI-TASLSAs 89   Leishmania major
XP_003723090   27 NWGPSIAG-EATPCFKGg-----------FLYRIIDSKKklWALYNDTFVYEMHATFIFGTASNMQ----PITTTSSSVs 90  
CAM70368       71 NACTV-VGGEVKFYFEGg-----------IIFCIVK--EgsWYVYNDSLDYEAHVTVRFGPGSNIV----AGERAELEEv 132 
Q4CP00         67 vmearqatyKYGKCTVEggegssffpprgLC-HLIKKDd-tWFLHNDTMNYEMHVNCKFSPDSSVI----PLGSSIKKDe 140  Trypanosoma c...
Q57WJ7         75 viaakqstfmYNKCTVTgevtpf-fppkgRCFRIIDEEg-rWFFYNDTMNYEMCVQAFFSPDSDVK----HCGTTTIKSi 148  Trypanosoma b...
Q57XZ9         58 viavketgfvYNKCTVTgevtsf-fppkgQCFRIIDEEg-rWFFYNDTMNYEMCVQVVIAPESYVE----HCEATTVNTk 131  Trypanosoma b...
CAM44092     1295 NGTPGISGDEVSACF-Gng--------ngLLFRIIDKATkrWAFYNDTTNFSMHIYFSVGRASTVEwgpdVAGRVT---- 1361
1R75_A         88 ddpdegNEDd------FGK-YLCEVDVRPLETQMFVEGSVTGWRVD 126  Leishmania major
XP_001567058  215 ----------------AGAeQELAMELGPEETKVFLTGRVMGFDSL 244 
Q4Q6M3        257 a--------------gTGE-TEITIAVLPEETNFFMSG--VAHMPH 285  Leishmania major
Q4QCS6         90 esggevDERnrvvasvEDNeLTISMVVYPMETIEFARGDKSKYRCH 135  Leishmania major
XP_003723090   91 enggevDGKnrvvasvEGNgLTISMVVYPMETIEFARGDKSKYSCH 136 
CAM70368      133 ---------------eDGW-TCAHAVVYPLETVHLVSGTANGYRTS 162 
Q4CP00        141 ---------------eDGS-AIVSAVVYPLDTVEFLCGEKGMYRSD 170  Trypanosoma cruzi
Q57WJ7        149 ---------------rNGL-TVISAFVYPLETLEFLSGSVELGAMY 178  Trypanosoma brucei
Q57XZ9        132 ---------------eNGE-TVISAVVYPLETLEFLSGSVVLNTVD 161  Trypanosoma brucei
CAM44092     1362 ------QAEs------TGW-YEGDLLVPPLATKVLMTGHVNGYKMR 1394
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