Conserved Protein Domain Family
SymE_toxin

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pfam08845: SymE_toxin 
Toxin SymE, type I toxin-antitoxin system
SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.
Statistics
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PSSM-Id: 370150
View PSSM: pfam08845
Aligned: 22 rows
Threshold Bit Score: 54.6456
Threshold Setting Gi: 81638289
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6D1N5    27 FTANTLfrinlyrnglmltllnedtdiAALMAELDGNeaegadwvsdNGELTLAGDWLTQSGL-PDQPLIIEVLPGRITI 105 Pectobacterium atro...
Q8Z0W8    20 NRHLTV---------------------SYASRYPDYTr---------IPALTMKGQWLEAAGFaTGTEVDVRVMNGCIVL 69  Salmonella enterica...
Q2SFN5    22 QRRLKVr-------------------kGYYDYHLSSSrydyg-gfkpVPWMLIKGYWLEQAGFgVDTEVEVSVSEGRIVF 81  Hahella chejuensis ...
Q664Z9    30 FTPGAVfkiqqyrngliitlianeiatQQVFNEIENDhhigmdwiqdNGELSLSGEWLTQTGL-TGQPLAISVMAGKVIV 108 Yersinia pseudotube...
Q57SW6    11 SRVERL-------------------------------------------SVRLYGEWMPQAGFiNGMPVKVRVMRDCIVI 47  Salmonella enterica
Q7N1T9    16 ERFGKVa----------------------------------------KNGISLKGKWLQEAGFtFGMPLKIRVMPDCIVI 55  Photorhabdus laumon...
Q6D1M7    19 ERFTRV---------------------GYRPIKGNHA----------TPAINIAGQWLKDAGFtTGQPLRLRIMPGCIVI 67  Pectobacterium atro...
Q6DA58    11 ALLHLI---------------------SYVSRRHADRsdmtr-yysrSPSLHLQDHWLEAAGFeIDIPVVITVEQGQLVI 68  Pectobacterium atro...
Q7M779    16 RRSYKV---------------------GYARTRHEDRstgmtryysqHPSLHLKGNWLEEAGFaTGQPVQVSVEHGQLII 74  Photorhabdus laumon...
KFZ96598  16 QRRYKV---------------------GYVRARHQDRktgiaryysqHPSLHLKGDWLKEAGFdTGRGVTVKISEGGLTI 74  Shigella flexneri
Q6D1N5   106 RA 107 Pectobacterium atrosepticum
Q8Z0W8    70 TA 71  Salmonella enterica subsp. enterica serovar Typhi
Q2SFN5    82 TA 83  Hahella chejuensis KCTC 2396
Q664Z9   109 RG 110 Yersinia pseudotuberculosis
Q57SW6    48 TP 49  Salmonella enterica
Q7N1T9    56 TA 57  Photorhabdus laumondii subsp. laumondii
Q6D1M7    68 TT 69  Pectobacterium atrosepticum
Q6DA58    69 RP 70  Pectobacterium atrosepticum
Q7M779    75 RL 76  Photorhabdus laumondii subsp. laumondii
KFZ96598  75 IA 76  Shigella flexneri
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