2AZE


Conserved Protein Domain Family
DP

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pfam08781: DP 
Transcription factor DP
DP forms a heterodimer with E2F and regulates genes involved in cell cycle progression. The transcriptional activity of E2F is inhibited by the retinoblastoma protein which binds to the E2F-DP heterodimer and negatively regulates the G1-S transition.
Statistics
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PSSM-Id: 400917
View PSSM: pfam08781
Aligned: 38 rows
Threshold Bit Score: 123.471
Threshold Setting Gi: 74920311
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2AZE_A         5 QECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRha-eqQASrPPPPNSVIHLPFIIVNTSKKTVIDCSISN 83 
XP_004989344 114 QEYKQYEELKAKKLESIRRANEQLNDLILQQIAFKNLIKRNEqreqeQPG-GVGDASKVQLPFIVVNTSKDAVVDCFMSH 192 Salpingoeca ros...
EDQ93069     108 QEARTYAATKRKKEEQVQKLKKQLQALVLQHIAFQNLIKRNQar-mqENP-STEEHDSIQLPFVIVSTRQSAVIDCQMAA 185 Monosiga brevic...
XP_016664633 235 QNSVYLVQEKENRLNSVKRKLLALQEIIMQEVAIKRLVKRNQdm-enEFG-PPPNNTFVNLPFMAISANEDTSVEVEISE 312 pea aphid
EFH49312     138 KDVEEVKMDRNKVMNSVQKKAAFLKELREKVSSLESLMSRNQem-vvKTQ-GPAEG--FTLPFILLETNPHAVVEIEISE 213 Arabidopsis lyr...
Q9FNY2       189 SDIEELKNERLSLRNRIEKKTAYSQELEEQYVGLQNLIQRNEhl-ysSGN-APSGG--VALPFILVQTRPHATVEVEISE 264 thale cress
XP_006651049 165 NDIEDLQTELLGLKSRIEKKNAYLQELQDQFVGMQKLIQRNErl-ygSGN-IPSGG--VALPFILVQTRPHATVEVEISE 240 malo sina
Q84VD5       187 SDVEELKTEIIGLKGRIDKKNAYLQELEDQFVGLQNLAQRNEql-ygSGN-APSGG--VALPFILVQTRPHATVEVEISE 262 Japanese rice
XP_001948131 127 QESTTLTREREELMARLNEKQAFLHELIVQQVTFKQLVEKNKky-eqIHG-RPSSASVLSLPFIAIKADPGTVIDCSISQ 204 pea aphid
XP_015697184  87 NDVDDLKAQIFGLKGRIDKKNAYLQELQDQFVGLQNLAQRNEql-ygSGN-APSGG--VALPFILVQTRPHATVEVEISE 162 malo sina
2AZE_A        84 DKFEYLFNFDNT-FEIHDDIEVLKRMGMACG--LE-SGSCSAE--------D---LKMARSLVPK--ALEPYVTEMA 143
XP_004989344 193 DRTEYLFKFNTP-FEIHDDVDILKRMGLAFG--IE-EGTCTDE--------E---VEEAKKMIPT--ALAPFLEDMV 252 Salpingoeca rosetta
EDQ93069     186 DQSEYFFDFNEP-FVIHDDLQVLSQLGLTFG--LE-TGAISDE--------Q---VALARDLLPA--EMGHILDEMV 245 Monosiga brevicoll...
XP_016664633 313 DQKQYGMSFNDK-FSMVDDTEILKTMGFTLG--LD-RGEVSNE--------D---LNILKTLVPK--AFEKHIVMMA 372 pea aphid
EFH49312     214 DMQLVHLDFNSTpFSVHDDAYILKLMQEQKQ-----------Q--------Q---NRVSSSSSTH--HQSQHSSAHS 266 Arabidopsis lyrata...
Q9FNY2       265 DMQLVHFDFNSTpFELHDDNFVLKTMKFCDQppQQpNGRNNSQlvchnftpEnpnKGPSTGPTPQldMYETHLQSQQ 341 thale cress
XP_006651049 241 DMQLVHFDFNSTpFELHDDSYVLKAMSSCGE---QnDGIHDLI--------P---NGGESSSMPN--IYRQQMQQPA 301 malo sina
Q84VD5       263 DMQLVHFDFNSTpFELHDDSFVLKALGFSGK---EpDDTQAWV--------G---NGGECSTTP---IY-HQSPQVA 321 Japanese rice
XP_001948131 205 DKKEYLFGFSNS-YEIVEDMDLLKSMNLSLG--LN-TGTSTAD--------Q---LEQAKTCVPK--KLHEFLSRIA 264 pea aphid
XP_015697184 163 DMQLVHFDFNSTpFELHDDSFVLKALGFSGK---EpNGAEDQV--------A---NGGECSSTPN--IY-HQSPQVA 222 malo sina
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