Conserved Protein Domain Family
GET2

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pfam08690: GET2 
GET complex subunit GET2
This family corresponds to the GET complex subunit GET2. The GET complex is involved in the retrieval of ER resident proteins from the Golgi.
Statistics
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PSSM-Id: 400847
View PSSM: pfam08690
Aligned: 31 rows
Threshold Bit Score: 178.75
Threshold Setting Gi: 121780541
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011274764   3 SEAEKRQKLRERRAAKIKNG--ASRLGKITGDYSEAQKDAetirTNPLSspet-----------------ksptPEPSIG 63  Wickerhamomyces...
EHK49016      16 rAAEQARLRKERREAKIKAGg-SARLERITGAGGRVTGDSgt-------------------------------tTPSGPD 63  Trichoderma atr...
XP_013958705  17 rAAEQARLRKERREAKIKAGg-SARLERITGVGGRVTGDSqp-------------------------------tAPSAPA 64  Trichoderma vir...
Q2GVT9        15 raAEQARQRKARREAKIKAGa-ENRLNRITGLGGGVPRDPap-------------------------------aPAASKT 62  Chaetomium glob...
CCE41938      11 SEEEKRRILRERRQAKMAKGkaSDRLNNILTQGASVKTSTv---TSVLDkpe--------------------paAATALP 67  Candida parapsi...
A5DSM4        10 TEAEKRKLLRERRLAKMAQGkaSDRLNTILSQGSSVKSVSppavTSVLEnkatkstdtatvtdsstnatsvspsAAKATP 89  Lodderomyces el...
C5MBE2        12 SAEEKRRLLRERRQAKMAKGqaTDRLNNILSQGSSVKTTGv---KSVLDepq--------------------ptAT---- 64  Candida tropica...
EMG49598      12 SAAEKKRLLRERRQAKMAKGqaTDRLNNILSQGSSVKASGv---KSVLDeek--------------------psIP---- 64  Candida maltosa...
C4YCC3         5 SAEEKRKLLRERRQAKMAQGkaTDRLNNILSQGSSVKSSNv---TSVLDkpe--------------------kaTTTVMD 61  Clavispora lusi...
C4R3U0         5 TEAEKRQLLREKRKAKLSQGggLDRLKKITGENNSKLSTDvp-------------------------------tKEPTAD 53  Komagataella ph...
XP_011274764  64 KETPISKSSGASkrisqsfDHE-DP--EVEDisnfepikesskessRANQPSDQLDEAQ-----QFEqMLQQMLGSvphQ 135 Wickerhamomyces...
EHK49016      64 ASSTAPAAT----------EHH-DP--AEVDisehffapkktsrkpIDGVFSP--SPEPslseaQLRqMMLGLDRP---E 125 Trichoderma atr...
XP_013958705  65 TLSKASTSD----------EHAtDP--AEVDisehffvpkktsrkpLDGVFSP--SPEPslseaQLRqMMLGLDRS---D 127 Trichoderma vir...
Q2GVT9        63 ATATTTPSAPVSta---aaQHA-DP--DEVDisehfyqp---------qttarvpPPDSnlsdtQLRqMMLGFDQP---G 124 Chaetomium glob...
CCE41938      68 TALTHDD--------------D-DP--DIQDisti---------tasdPPLGEK-DPQV-----EMNeMFKSIFQQ---Q 112 Candida parapsi...
A5DSM4        90 TSTGVSSAISDF---------D-DP--EIQDisdvavnnsgvlalgNLSGLDSN-NPSQp----NLDeMFQKIMQQ---Q 149 Lodderomyces el...
C5MBE2        65 ------SSAIHD---------E-DP--DIQDiseias------pppptPPIGEG-SPE------NIDdIFQKMLQQ---Q 110 Candida tropica...
EMG49598      65 ---------EHD---------D-DP--DIQDiaeiai------ppaptPPIGEE-PPQ------DIDsIFHKMLNQ---H 107 Candida maltosa...
C4YCC3        62 LPSRETQSPTPL--------HD-DP--EVPDitsl----------------lkekENEAp----DMEaMLQQILGG---S 107 Clavispora lusi...
C4R3U0        54 ATTTATELPTQGlet-rinAHD-DPvsEIPD------------------PLNEGFDGKEp----DLDqLIASMF-----N 104 Komagataella ph...
XP_011274764 136 HQGDSNNSTDAPQGTPdfD-IFSKLLSGDANGQGNpfgslgsmgalqqtqaqknqsqgydpahpDVNLEQIEYQKQLSEY 214 Wickerhamomyces...
EHK49016     126 QAGP-PGGNPAGMNLPpgM-EDDPIMKMMSQMMSSgsipgfgg--------------adgapnpFGNMQMPQQQAPVELP 189 Trichoderma atr...
XP_013958705 128 QPSPVPGAT--GPALPpgM-EDDPIMKMMSQMMSSgsipgfgg--------------adgasnpFANMNLPQQQAAVQLP 190 Trichoderma vir...
Q2GVT9       125 TATPPMPGMPGMPSPPpgM-EDDPMMRMMMQMLGGggnnpfgggm---------pgmpfppsttPGSGAQPFPPQPQQSA 194 Chaetomium glob...
CCE41938     113 QQSSQDDAN-----------PMAEIFKMLGDPNSVddq-----------------------niqSPNSAQSQYEQQLNQY 158 Candida parapsi...
A5DSM4       150 SQHNCDNDNNGEN-----N-PMAEMLKMFNSMGGGdnngglggfdsm------fsgspnspppeSISPEMMKYQADLAKY 217 Lodderomyces el...
C5MBE2       111 VQGKDGKVDPN-------D-PIVQIMNMFKDGSGAdgpqegd----------------vnanefSNDPVENKYQQDLQAY 166 Candida tropica...
EMG49598     108 TQGKISDDPN--------D-PLNQIMKMFNEGGAGanlpnd------------------stqafSDDPVEAKYQQDLQAY 160 Candida maltosa...
C4YCC3       108 GAHTGPGNDGGAN-------FLQEMMKAMAEDPSG-----------------------------GSTAEESSYQSQLSQY 151 Clavispora lusi...
C4R3U0       105 KSAGHENPNSEEQGVPelMrRFSSILQGGDSGAAGlgaeagginpldllnslggsnigkaqeeyGSTPEEIEFNKKSIAY 184 Komagataella ph...
XP_011274764 215 NKIQNDKFKAKFMLFKFIISFg-LTIYFFgi--qgFYSSSV------------EIFRIHKLDS----GFSKIWLTLEILF 275 Wickerhamomyces...
EHK49016     190 KSSSVTLWRVVHALVAIGMGLf-FILTTH------FTGSKIerer----malaHEQEVDDEMErrknLFFWTFATAEVLL 258 Trichoderma atr...
XP_013958705 191 KSSSVSFWRLIHALVALGLGLf-FVLTTN------FSGSKVerer----talaFEQEVDVEAErrknLFFWTFATAEVLL 259 Trichoderma vir...
Q2GVT9       195 TNRHATLWRLLHALIALALGLy-IAVYTP------FTGSKLsrdsaaaaaagsAEARADFGASps-qNYFWAFATAEALL 266 Chaetomium glob...
CCE41938     159 HMYQKQVWKFRFSVVRFLTIVt-FFFYHYcsi-psFTSSNH------------AYVRDLTEVYpl-sGFAQGFFTLEVAI 223 Candida parapsi...
A5DSM4       218 HTYQEQLWQFRFLVVRILATIf-NFAYHFiti-psFTASNH------------AYVRDLSEVYpl-lGFMTIFTSIEVVI 282 Lodderomyces el...
C5MBE2       167 DTYQQKLWKSRFLVIRVVVTLf-NFFYHYlnv-psFHASNY------------SYVRDLAQDEfpvrNFFTWFAAFEVII 232 Candida tropica...
EMG49598     161 NTYQQKAWKFRFLVIRAMLTLf-NFFYHFvtl-psFQASNY------------TYVRDLSNDEdpvrNFFTWFATCEVVI 226 Candida maltosa...
C4YCC3       152 HAYEQKQWKARFLVVRWIIHTl-NFVYHYiasgykLSASPY------------AFVRAQAVDShv-rTFFTAFLTVEVAV 217 Clavispora lusi...
C4R3U0       185 KKHQNEVLKAKILVVRLVLILslLFVYGRdfs-------------------lsLFTQTYAPNGs---SFMRVFLTLELIF 242 Komagataella ph...
XP_011274764 276 TSYYALHLNKIQDSHY----NYNSKILKILGYVPDMFLS--PYYKNKIRWFVKYQELIHLIIFDLSVIIFLFGILS 345 Wickerhamomyces cif...
EHK49016     259 LSTRLFLDKKST--------NATGFIATAISYLPQP-------YRGYIEIGQRYIQIFTTVRTDILTCIFVLGVVS 319 Trichoderma atrovir...
XP_013958705 260 LSTRMFLDKRST--------NATGFVATAISYLPQP-------YRGYIEIGQRYFQIFSTVRTDILTCIFVLGVVS 320 Trichoderma virens ...
Q2GVT9       267 LGTRHFVADRGRSRLQaaaaGGSGMLGMAVGFLPAG-------LRSKVELAMRYGEVLGSVRADVLVCVFVLGVAa 335 Chaetomium globosum...
CCE41938     224 IASYYFIL---TKNGLfhaaRQNNLVMKGVQ-IVSMFAPqvQQFAPILSRVLEYKELLGIFLVDLSIVVVLFGLLS 295 Candida parapsilosis
A5DSM4       283 IATYYLLF---TKLGLfhasNQKSFILKGIS-TLSMFVPqlLRYEPLVATFLGYKELLGIFVGDLSLVVVMFGLLS 354 Lodderomyces elongi...
C5MBE2       233 VLQYYTVF---HKLGLfhaaNQNSMIMKLMS-MGSMVLPqlNTYQPLVARFLGYYELFGIIFGDLSLVIVLFGLLS 304 Candida tropicalis ...
EMG49598     227 VATYYSVF---HSLGLfhaaNQNSIVLKLMS-MGSMVLPqlAAYQPLVARTFGYFELIGIIVGDLSLVIVLFGLLS 298 Candida maltosa Xu316
C4YCC3       218 ISAYFLVM----SQPKfkdfSRENLVSRILS-MASAVVPavGRYQPLVTRALVYWNGASIFVGDLMLMVFYFGITS 288 Clavispora lusitani...
C4R3U0       243 QTSLFFFI---SKNKNf---TDDSLISKLLN-IGGAFIP--ATYRNLLQTASKYQVLLSMFLFDLSIVVVVFAira 309 Komagataella phaffi...
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