Conserved Protein Domain Family
DASH_Dad2

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pfam08654: DASH_Dad2 
DASH complex subunit Dad2
The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro.
Statistics
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PSSM-Id: 400816
View PSSM: pfam08654
Aligned: 55 rows
Threshold Bit Score: 79.1838
Threshold Setting Gi: 599406046
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6CXI8         4 ETEIETKRRELNYLKHVSALTQKLKAQLDELSVQVAQMNSNAVTVKDVMANWDSVLRSISQASISLLqYTENdyetgkwa 83  Kluyveromyces l...
XP_004178233   7 ehiLREKTAELQALKQITSLTDNLKVELEQMAIQTSKIRDNSASVSEVTDHWNSILRSISQASLKILqYTQSdyevgswk 86  Tetrapisispora ...
CCF57856       5 rEQLLSKERELAALKKIAALTDTMKLQLNELSDEVKQIEGNAQRVNDVMSIWNSVTRSISEASLGLLrYVEKdyevgiwd 84  Kazachstania af...
CCK73040       5 EEQMSAKREELETLKKITELTNTMKSQLDELSDQVGEIEASGESIANVVKLWDSVTQSISAAGLGLLrYGEKdykvgqws 84  Kazachstania na...
CCD22475       4 telLISKQRELEALKKITTLTDNMKIQLDELSIQVSKLEHNASVVGDVTSIWDSVLKSISQASLGLLqYSENdyevgvwn 83  Naumovozyma dai...
CCC66890       6 dpQIYSKRQELEALKKITALTDTMKLQLGELSEQVQMMENNVDSVARVTAIWDSVMKSISQASLGLLqYAESdyevgvwd 85  Naumovozyma cas...
Q6FTI5         5 eQQKLAKQQELAALKRITALTDQMRTELDEMSIEVSKINKNAESVANVMANWDSIRKYISEASLGLLrYAEGdyqvgawd 84  [Candida] glabr...
XP_003687399   5 EAQIENKRQEFEALKKIVGLTDTMKVQLDALSNEVTQMHSNADSVSQIMLHWDSIMQYISQASLGLQkYSEGdynvgtwd 84  Tetrapisispora ...
CAR24522      49 EDQIASKRRELEALKKINTLTNSMRLQLDGLAVEVKKMHENAENTANVMKNWDSIVRSISQASLSLLqYSEGdyevgiwd 128 Lachancea therm...
CCA73078      22 rEAVLAKRREYLALCAIAEYAAHLENNLKATAQQQALMTDGGAALSKAMGNWLVIMRTIGMYSKEVAaREDL-------- 93  Serendipita ind...
Q6CXI8        84 skeEHRNQQGAEDESaasessednqqrqqdqlpPLPETLVRVKV 127 Kluyveromyces lactis NRRL Y-1140
XP_004178233  87 nenNATEKDEDKDNAv-----------------PLPETLVRIRT 113 Tetrapisispora blattae CBS 6284
CCF57856      85 ddnVDGDISKTNSSNdeamdksse-eirqqkeiPLPETLVRVPI 127 Kazachstania africana CBS 2517
CCK73040      85 edaEKKKEADTM---------------------PFPEGLVRVNk 107 Kazachstania naganishii CBS 8797
CCD22475      84 nnnESRDDIYNEDKKtg---------------iPLPETLVRIRA 112 Naumovozyma dairenensis CBS 421
CCC66890      86 essQGKNRRLDNDEDsqlene-------nekvlPLPETLVRITa 122 Naumovozyma castellii CBS 4309
Q6FTI5        85 gkeNKSDKSNADKSYqsdde---------hktePLPEALVRISV 119 [Candida] glabrata CBS 138
XP_003687399  85 dskTSKDKQEDKEQKes--------------elPLPETLIRMKI 114 Tetrapisispora phaffii CBS 4417
CAR24522     129 qdqKRSDEREESESEp-----------------PLPETLVRVKV 155 Lachancea thermotolerans CBS 6340
CCA73078      94 ---INAEQPTDTTSDdp---------------eAHKRILLRVel 119 Serendipita indica DSM 11827
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