Conserved Protein Domain Family
SPT16

?
pfam08644: SPT16 
FACT complex subunit (SPT16/CDC68)
Proteins in this family are subunits the FACT complex. The FACT complex plays a role in transcription initiation and promotes binding of TATA-binding protein (TBP) to a TATA box in chromatin.
Statistics
?
PSSM-Id: 400807
View PSSM: pfam08644
Aligned: 76 rows
Threshold Bit Score: 108.406
Threshold Setting Gi: 387593240
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
ESS30113  672 LYVDFKSESLLVPIHGSHLPFHLSTVKNVtcseaqgdssgSSSVSGKnkapfyVLRINFQVPgsqtltl-kgeenplPDL 750  Toxoplasma gondii...
A0E089    521 IAVDQDKSAILIPIIGTHYPFHALTIQNV-----------SVKELPNga---gEITIRFWTNefhid------trefPSM 580  Paramecium tetrau...
Q580R3    507 IYVDTEKEVAFFPVCGGVAAFHVSTISRV-----------DVKFEGNq----vAGIFSFHSLqegni-----ayrlnRTK 566  Trypanosoma brucei
EIM22979  552 ILVDTKAQTVILPINGFIVPVHVSTIKNI-----------SKTEEGDy----tSLRINFITPgqsvgkk-edvpfedPDS 615  Wallemia mellicol...
EGF81416  531 ILVDRRSETIILPVFGQAVPFHVSTLKNV-----------SKSDEQDf----vLLRFNFITPgqstgkkegpmpfedPNA 595  Batrachochytrium ...
EDP43799   91 IMVDHRAQSIILPINQFAVPFHIKTLKNV-----------SKSDEGEf----tYLRINFVTPgqlsgkk-edvpfddPNA 154  Malassezia globos...
Q4P2U5    545 IMVDHRAQSIILPIYGYAVPFHINTLKNV-----------SKSDEGEy----tYLRLNFVTPgqiagkk-edvpfddPDA 608  Ustilago maydis 521
EIJ88264  497 IKVDRRAFSVIIPVFGAAVPFHIDVIKTA-----------TKTIEDGi----gYLKISFYQPdrd----------vpTSA 551  Nematocida parisi...
Q8SW60    399 LIVDFARESIVVPIGSYAVPFHVSSIKSA-----------AVTDDK-------ILRINFKTEskgk--------eetEEA 452  Encephalitozoon c...
ELA41807  396 IHLDWDNFFVLVPILSYSVPFHISTIKNV-----------SIVNPNDe----pRLRINFKESkeikeaf----------- 449  Vittaforma cornea...
ESS30113  751 sgk-pdtVF---IKELMFKSEDGRHLQTIFRTIKEQLKRVKQKALEDD--VAGEVTEQDKL-ILNRsgrrvLLKDLMIRP 823  Toxoplasma gondii...
A0E089    581 dq---dqMF---LKEITLRNQEFIKLQDIENEINVCRDDARRKQIEKQleVDKFDFVIEKLtVLPKnt--pCLSKVYMRP 652  Paramecium tetrau...
Q580R3    567 -------IF---VKELTYRARRDI-FTDVKIAIQGIQQRIKNRDTERR--RVSLNAGGAQLqTVPDa---iRLPQVKIRP 630  Trypanosoma brucei
EIM22979  616 -------MF---IRSATFRSTDKLRFSDLYKDITELKKLSTKRAAEKR--EMADVVEQENL-TEIKgrrpvRLGEVFARP 682  Wallemia mellicol...
EGF81416  596 -------TF---VRSLSYRSNDIGRFTEIYREINELKKEMQKRDAERL--EMADLVEQASL-MEVKgrrptRLPDVFVRP 662  Batrachochytrium ...
EDP43799  155 -------TF---IRNVSYRSTNTRHFDDLYNEITEMRRIAAKREAEQK--EMADVVEQDEL-ILNKhr-plSLPEVFPRP 220  Malassezia globos...
Q4P2U5    609 -------TF---VRSMSYRSSDSSRFTELFREITELRKSATKREAEEK--ELADVVEQDKL-ILTKsr-ayTLPEVFPRP 674  Ustilago maydis 521
EIJ88264  552 -------NN---LLSLVIKDTQEN-VMTAWKEINNLKKE----EEETE--EEIEEGEQEDL-QEIAgr-veTLQNVFMRC 612  Nematocida parisi...
Q8SW60    453 eceqrgeSFlstIKSISIRGNN---SRDLLEEINSLKKGHLTKET------IEDVESLEELkISSRp---lSLTDVYMKT 520  Encephalitozoon c...
ELA41807  450 dvnkecdTK---IKFITLRCGN---VEDMISQINEMRKEFNKP--------KISLPTQPVLkEKFKk---yALPEVYMRT 512  Vittaforma cornea...
ESS30113  824 NIApGm--RKLIGALEAHTNGLRF 845  Toxoplasma gondii VEG
A0E089    653 TQSqKt--RSPEGFVECHENGFRY 674  Paramecium tetraurelia
Q580R3    631 PATtGrynKECIGNLEIHRNGLRF 654  Trypanosoma brucei
EIM22979  683 -IE-G---KRLAGDLDIHTNGVRY 701  Wallemia mellicola CBS 633.66
EGF81416  663 GLE-G---KRFPGDLEIHLNGLRY 682  Batrachochytrium dendrobatidis JAM81
EDP43799  221 ALE-G---KRVPGNLTIHQNGVRF 240  Malassezia globosa CBS 7966
Q4P2U5    675 AME-G---KRVPGDLTIHQNGLRF 694  Ustilago maydis 521
EIJ88264  613 DHRmGt-kKNVANTVELHKNGLRY 635  Nematocida parisii ERTm3
Q8SW60    521 DIRtGs-rKRKVGNLELHENGFRF 543  Encephalitozoon cuniculi
ELA41807  513 DNKsAn--KKILGNLELHENGFKY 534  Vittaforma corneae ATCC 50505
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap