Conserved Protein Domain Family
RNR_inhib

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pfam08591: RNR_inhib 
Ribonucleotide reductase inhibitor
This family includes S. pombe Spd1. Spd1p inhibits fission yeast RNR activity by interacting with the Cdc22p.
Statistics
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PSSM-Id: 400764
View PSSM: pfam08591
Aligned: 41 rows
Threshold Bit Score: 41.2358
Threshold Setting Gi: 74607449
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EPE07517      59 NLLAVGMRVRKSVPEGYKTGK----------------EADERTTPSHYRPQPKAPSSYAssyrtflq------sagrpaa 116 Ophiostoma pice...
EMD94723      75 DLLSVGMRVRKSVPEGCKTHKmls-----------spADRFARARPRLDIKPPPEAVPD--------------------- 122 Bipolaris maydi...
CBX99698     196 DLLNVGMRVRKAVPGGYKTQKlmsglptitttlvhspTTALA----DYEVKPSRDTVED--------------------- 250 Leptosphaeria m...
Q6CD17        38 QLASVGMGIRKSVSDGHKTTGnh------------naSLRHESFTPVADVQNPLRGTYGpasslggyitksfsaapelgl 105 Yarrowia lipoly...
CCE82863      25 SLATVGMRVRKAVAEGYNVPD----------------------------------------------------------- 45  Millerozyma far...
Q6BME9        25 SLSTLGMRIRKSVADGYNVPS----------------------------------------------------------- 45  Debaryomyces ha...
XP_001268750  65 SLLSVGMRVRKSIAEGYKTKGv--------------------KLFDESTRRPSELEQHSig------------------k 106 Aspergillus cla...
Q4WRU7        65 SLLSVGMRVRKSVAEGYKTKGv------------------KMFDTPTSTISLSAKHEHStg------------------r 108 Aspergillus fum...
EPS25475      71 NLFDVGWRVRKAMAEGYKTQRsmkaekaqeivtptepRVALSSLPPNHTHTLTHSHTHTda------------------y 132 Penicillium oxa...
CAP97226      67 SLLSVGMRVRKSVAEGYRTQMs---------------KTEEKAPLPTAVAQTPRAQPY---------------------- 109 Penicillium rub...
EPE07517     117 pPTPSQRELLPFCG--LNKVG----GLDVQsygdedGRPmfas-slfeEMDDGATAVASDSEPPA----LT------SSQ 179 Ophiostoma pice...
EMD94723     123 -HYQHQRELLPFCG--LYNIG----GFAEQpttnphLYTtsp---trqRPAIAFPLTADAFTQPF------------PDQ 180 Bipolaris maydi...
CBX99698     251 -RLTHQRELLPFCG--LNKIA----GYAEQpttnrhLYGgghd-satqESTNLFPLSAEAFTQPF------------SSQ 310 Leptosphaeria m...
Q6CD17       106 gSANKDREVKGYKG-----IG--------------------------------------------------------AER 124 Yarrowia lipoly...
CCE82863      46 ------RDRYDISGfsQNGMDyarnDVGQHtaeennSTG---------FRVPQRVPLPAHMDGPPglsdSLstaessSNL 110 Millerozyma far...
Q6BME9        46 ------NKYNGYNA--YDRMGytshGEYGRvepkaiGIFggnqdgsniDYEPARVPLPTHMSQPPaltnVGstigtcSNL 117 Debaryomyces ha...
XP_001268750 107 nYPAIRAELAPFCG--MSKAG----DFAIQsyadpsCHSldh----mdHTNQIIMDDGDAFSLPP------------SSQ 164 Aspergillus cla...
Q4WRU7       109 gFPTVRGELAPFCG--LSKSC----DYTVEphsntvYELset----rgYNVDIVTDDGDAFSLPP------------SSQ 166 Aspergillus fum...
EPS25475     133 aHTPRRAELAPFSG--LSKATh--------------------------DPYSVMTDDGDAFSLPP------------SSQ 172 Penicillium oxa...
CAP97226     110 -HGSRPSELSPFSG--AGKSSfgrdDYLV-------------------------TDDGDTYSIPP------------SSQ 149 Penicillium rub...
EPE07517     180 ETV 182 Ophiostoma piceae UAMH 11346
EMD94723     181 SSA 183 Bipolaris maydis C5
CBX99698     311 GST 313 Leptosphaeria maculans JN3
Q6CD17       125 YSL 127 Yarrowia lipolytica
CCE82863     111 SDW 113 Millerozyma farinosa CBS 7064
Q6BME9       118 SEW 120 Debaryomyces hansenii
XP_001268750 165 ESV 167 Aspergillus clavatus NRRL 1
Q4WRU7       167 ESV 169 Aspergillus fumigatus
EPS25475     173 ESI 175 Penicillium oxalicum 114-2
CAP97226     150 ESA 152 Penicillium rubens Wisconsin 54-1255
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