Conserved Protein Domain Family
Iwr1

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pfam08574: Iwr1 
Transcription factor Iwr1
Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits. Deletion of this protein results in hypersensitivity to the K1 killer toxin.
Statistics
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PSSM-Id: 400751
View PSSM: pfam08574
Aligned: 96 rows
Threshold Bit Score: 29.1597
Threshold Setting Gi: 309356116
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EED21949     400 GDYVYDTYVRVpihtvtssvsgaapqsditgyedplaeaN-TPGGITIDPTRTDVGVVV--ITSDDEELWd--------- 467 Talaromyces sti...
XP_002500627 259 DKYVYDVYVRAdddde-------------------eddeGaNSKFVGDVNAKANLASLI--YVNSEDAALf--------- 308 Micromonas commoda
EDX05562     191 VGYVYDLY-----------------------------------------VPENEMQAAY--VDMMDDNYLrvipvgei-- 225 Drosophila simu...
ETN64751     172 VRYVYDLYVAd---------------------------tSqQQNIAHSPYYTDNLDDLS--VMVCDDPLYslh------- 215 Anopheles darlingi
XP_001847835 145 PGFVYDLYVVd---------------------------eS-QQQSQHVPYIPENLDDIS--VAIYDDPLYssh------- 187 southern house ...
Q17FQ6       165 QDYVYDLYVAd---------------------------eA-Q-QQLHIPYIPDNLDDIS--VAIYDDPLYssh------- 206 yellow fever mo...
NP_001280455 137 IDYVYDLY-----------------------------------------------------YASNNDNKSidiqdidsvh 163 pea aphid
Q9XVH5       119 DDVVYDYY--Aih------------------------ekRgNPEVVGNLEQDIEGADFR--FAKRDELDL---------- 160 Caenorhabditis ...
1_pfamImport   1 EDVVFDYY--Rih------------------------ekRgNTWNSEMTDDIHEIEVK---FANRDELDL---------- 41 
CAP37777     121 dDVVYDYY--Aih------------------------grRgNPAGVEGENWDADIEGAEfqFANRDELNL---------- 164 Caenorhabditis ...
EED21949     468 -----QYLED----DQDSEvd-----wdGDDVDSNAEDNPANDYPDDE 501 Talaromyces stipitatus ATCC 10500
XP_002500627 309 ----eWMDGLaeeyDHEDD---------VDSQDSNREDAPDADYPEDE 343 Micromonas commoda
EDX05562     226 -------vledcynDQDED---------YDSEDSNQENYFTNDYPDDD 257 Drosophila simulans
ETN64751     216 ---rgDLD-S----DDSSD---------SDSDDSNAEDNWRNEYPDEE 246 Anopheles darlingi
XP_001847835 188 ---rgLGDRS----DSDGG----------ESEDSNDENNWRNDYPDED 218 southern house mosquito
Q17FQ6       207 ---rgLGDRS----DDSMG---------EESEDSNDENNWRNDYPDED 238 yellow fever mosquito
NP_001280455 164 gldsdNFYNI----CQNIDssdndsshcEDDDDSNDEGNWRNDYPDED 207 pea aphid
Q9XVH5       161 ---------------GDEDdsdg--ppaDDEDDSNDEDNWRNDYPDEE 191 Caenorhabditis elegans
1_pfamImport  42 --------------AGGEDsdg---ppaDDDDDSNDEDNWRNDYPDED 72 
CAP37777     165 ---------------PDDDedsd-gppaDDDDDSNDENNWRNDYPDED 196 Caenorhabditis briggsae
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