Conserved Protein Domain Family
CDC37_C

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pfam08564: CDC37_C 
Cdc37 C terminal domain
Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the C terminal domain whose function is unclear. It is found C terminal to the Hsp90 chaperone (Heat shocked protein 90) binding domain pfam08565 and the N terminal kinase binding domain of Cdc37 pfam03234.
Statistics
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PSSM-Id: 400741
View PSSM: pfam08564
Aligned: 29 rows
Threshold Bit Score: 68.121
Threshold Setting Gi: 334326301
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKM51968          400 GLEGVNPEDVr--rALQMRWDVFQGFAPAFQDALRSQSLDQVNKVLGNMKVEDAEQVVNMLDVAGILNFSEHGVRDDTgk 477 Phanerocha...
Q0UZ82            416 ppkepTSQEPeereAEVQARQIFENFPPGLQRALESGKLDEVNKVLAKMSVEEAEEIVEKLGQGGMLSLEQGVIDATT-- 493 Parastagon...
EHY57908          415 NVPQAGSDDP----VEQQAREIFDRFPPGLQRALESGSLDEVNKVLGKMSVDEAEEIVELLGQGGMLSLQEGVIDATN-- 488 Exophiala ...
EJP70180          382 SVPPKDSEDP----AVQEAREIYEHFSEEMRAALETGELDKVNAVLGELSVEEAEEYVSLFGEANILTLEEQIIDATT-- 455 Beauveria ...
XP_013946174      378 KVPPAVSDDA----DTQAARKIYESFDPEMRKALETGELDEVNKVLGNMKIDAAEELVGLFGEANILSLEEELIDATT-- 451 Trichoderm...
XP_006960976      389 TIPPADSDDP----DVMAARKIYDSFDPEMKDALESGSLDEVNKVLGKMKVEEAEELVAKFGEANILSLEEELIDATT-- 462 Trichoderm...
XP_013958787      380 RVPPADTEDP----DDQAARKIFDSFAPDMKKALESGELDEVNKVLGNMKVEDAEELVGLFGEANILSLEEELIDATT-- 453 Trichoderm...
XP_003442133      289 LGP--GGLDP---------VDVYESLPPEMQKCFDEKDIQMLQEVISKMDPTEAKAHMKRCIDSGLW------VPNAKgd 351 Nile tilapia
CDP32200          397 RIPPKDSEDL----DVQVGRAIFESFTPEMQKALETGSLEEVNKVLGKMSVEDAEEVVGKLSESGCLSVEEEVIDATT-- 470 Podospora ...
jgi:MYCTH_2304802 403 RIPEENSEDE----ETRKGRAIFDGFPEDMKRALQTGKLEEVNKVLGEMKVEEAEEIVGKLGEAGILSLEEEIIDATT-- 476 Thermothel...
EKM51968          478 anddgdgdEDGEGEEEEEEEE 498 Phanerochaete carnosa HHB-10118-sp
Q0UZ82            494 --------DEGKKAMEEIEKT 506 Parastagonospora nodorum SN15
EHY57908          489 --------EEGQKRLKEIEEE 501 Exophiala dermatitidis NIH/UT8656
EJP70180          456 --------EEGQQQVKELQAR 468 Beauveria bassiana ARSEF 2860
XP_013946174      452 --------EEGQKQLRDLEAA 464 Trichoderma atroviride IMI 206040
XP_006960976      463 --------EEGQKQLKAMEAA 475 Trichoderma reesei QM6a
XP_013958787      454 --------EEGQRQLREMEAA 466 Trichoderma virens Gv29-8
XP_003442133      352 dgeekgdeKDDEPTYEEIQHE 372 Nile tilapia
CDP32200          471 --------EEGKQKIKKLEQE 483 Podospora anserina S mat+
jgi:MYCTH_2304802 477 --------EDGKDKLKKLEES 489 Thermothelomyces thermophilus ATCC 42464
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