Conserved Protein Domain Family
Kei1

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pfam08552: Kei1 
Inositolphosphorylceramide synthase subunit Kei1
Kei1 is a subunit of Saccharomyces cerevisiae inositol phosphorylceramide (IPC) synthase. It is localized to the Golgi and is cleaved by the late Golgi processing endopeptidase Kex2. Kei1 is essential for both the activity and the Golgi localization of IPC synthase.
Statistics
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PSSM-Id: 400732
View PSSM: pfam08552
Aligned: 71 rows
Threshold Bit Score: 98.3946
Threshold Setting Gi: 74633519
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6C5A7               10 SFLWIFPLQQAAELIIALALFNKAYGLYALLCAFI-T---PLSFTQVVMALVSLALVFPYAMSIPVIRAlPvtgsgpgal 85  Yarrowia...
XP_011117506         14 HFLGFLDLKVGAELILLCSLFNKASGFYGLLAIFTgA---EISALQVSMYFYSVLAVFFIAWVQPHIRK-R--------- 80  Arthrobo...
CCX07338             12 KFLGYFDLHYGADIVLMSLLVNKCSGVFGVLAMLGgV---KFSAIQFSMYFYSLLLFALLCHIAPSIRS-R--------- 78  Pyronema...
XP_002841064         15 HFLGLLDLQHGAELILVCTLFNKISGLYGIIAMLVgA---EISTLQLSMYFYSLLMFGALIYTLPKLHQ-R--------- 81  Tuber me...
XP_007842922         17 SCLGFLDLKTGVTVALLFAVLNKVAGIYGLIAVVTgA---GGSFSQLSLYIYSVLALVALVWGLRAVKE-E--------- 83  Moniliop...
EKM81798             13 SFAGLLDLKTAVTVSLLFALFNKVAGVYGLVAVVTgV---GGSFAQLSLYIYSVVALIALVWGLRAVKG-E--------- 79  Agaricus...
XP_003033122          3 SFLGVLDLKTGVIVALLFALLNKVAGVYGLIAALTgA---GGSFAQISLYLYSTLALVAIALGLKAVKR-V--------- 69  Schizoph...
EGN92279             13 SFLGAFDLKTGVTIVLLFALLNKVAGVYGLIALLTgA---GGSFAQLSLYIYSVLGLVAFVWGLKVVKE-E--------- 79  Serpula ...
EMR08969             14 SFLYFLDLQIGTELIIFFSILNKASGIYGFFVTLInYsslSMSLWKMFMYFYSLLVLLGFTMMIKYIRI-E--------- 83  Pneumocy...
WGS:AATM:SJAG_03015  21 KFFGICGLQTGCEFIVWFSIVNKLCGIYGVLALFQsA---DVSFAEVTMYVCSFIFLFIFGWLSIYIPK-R--------- 87  Schizosa...
Q6C5A7               86 astmasispstmS-PkdiinkIPIVLL-AcVLYTFDLVLTIFSGVIF-AHDWAEDCEECDAAAAAStaasvsatlsDAVS 162 Yarrowia...
XP_011117506         81 ------------T-P------FPNITF-GyW-YLIDSIINATYTTIF-AITWFMVISEPRRSAFTDastap-gvgdSGKM 137 Arthrobo...
CCX07338             79 ------------N-P------LSAISF-A-YITLLDALINILYTLLF-GFSWFLVLAQKYHDASNPav------ksAAGT 130 Pyronema...
XP_002841064         82 ------------N-P------LAAITF-A-YLYLADSLINALYTLLF-GISWFLVLASKHNSAIHPik-------sAGET 132 Tuber me...
XP_007842922         84 ------------D-P------KQTLYF-A-HLFFADHIFSTSWTVYF-ATVWWFQ-NPHDGHHSAN----------SPAQ 130 Moniliop...
EKM81798             80 ------------D-P------KQTLYF-A-HLFFADHVVSTAWTVFF-ALAWWIW-IPHDGSRQA-----------NSPA 125 Agaricus...
XP_003033122         70 ------------RlP------SPPLYFrA-FLFSSTHALSTAWGHMVrPLSWWVQDAAWTGGAQA-----------HSAA 119 Schizoph...
EGN92279             80 ------------E-A------KHSLYV-A-HLFFADHVFSTSWTIFF-AVVWWLY-TPHDGRRQANsp-------aQDQI 129 Serpula ...
EMR08969             84 ------------S-P------FHILIC-A-YFYFIDTFISSLYSAIF-TIVWFMNIFKHAIISSGV----------GKLV 131 Pneumocy...
WGS:AATM:SJAG_03015  88 ------------T-V------FHALVF-S-YTYLIDSLINFLFLIFF-SISWFMHLVENAAIPDA-----------GVST 134 Schizosa...
Q6C5A7              163 ATATATATATAsvvssaasaatsavssavssaasATSALVSAATSSalnvatssvspddetrvrfglrdatdrdlSLDSA 242 Yarrowia...
XP_011117506        138 IEDISGLSGGPfnpvggad-------gtdaaapsYIETISGATAFD-----------------------------AFANG 181 Arthrobo...
CCX07338            131 IDQHAGFTSPAynvshia---------vspsgqeAVAIPASAVVPE-----------------------------SFSSG 172 Pyronema...
XP_002841064        133 MDDTAGFTPSEfnasevdvv------aypsasgqDTVVIGSGEGTS-----------------------------FLSSG 177 Tuber me...
XP_007842922        131 IEIIEGTVHSD--------------------------IPMTDEERV-----------------------------AAAQK 155 Moniliop...
EKM81798            126 QQAMIDAANIT--------------------------RLLTDEERE-----------------------------IEAMK 150 Agaricus...
XP_003033122        120 QEAMMHAAPPH--------------------------EPMTDAQRV-----------------------------AAAMA 144 Schizoph...
EGN92279            130 RKGGIGLNHTL-----------------------------TDAERE-----------------------------VAANI 151 Serpula ...
EMR08969            132 SSQKSEIIELW--------------------------SSNNSEYAH-----------------------------DNSIM 156 Pneumocy...
WGS:AATM:SJAG_03015 135 LTERADAGSAV------------------------------DNTTT-----------------------------GSTNP 155 Schizosa...
Q6C5A7              243 SRGQETAATIIIAVFLLLVRIYFALLLLSYGiklRALLKQL 283 Yarrowia lipolytica
XP_011117506        182 LNQPESMTSMAIIAGLWVVRAYFCLVVLAYA---RQVVRDS 219 Arthrobotrys oligospora ATCC 24927
CCX07338            173 VLQPESATSILLIAAFWVVRLYFIIVAFAWA---RQVVRAS 210 Pyronema omphalodes CBS 100304
XP_002841064        178 VLQPESSTSILIISVIWLIRIYFVIIVMAFA---REVVRGS 215 Tuber melanosporum Mel28
XP_007842922        156 IWNHEKGTAAAFIILAWILKLYLALLIYSYA---SHLRKGS 193 Moniliophthora roreri MCA 2997
EKM81798            151 IWNAEKSTAFIVITLSWLSKFYFALLIYSYA---SHLRKGS 188 Agaricus bisporus var. burnettii JB137-S8
XP_003033122        145 IWEQEKGFAAAIIAVSWLSKLYFALLIYSYA---SHLRKGS 182 Schizophyllum commune H4-8
EGN92279            152 IWNQEKGTAAAVIAISWLAKIYFAILLYSYA---AHLRKGS 189 Serpula lacrymans var. lacrymans S7.3
EMR08969            157 FFSIENLFTVFILCFFLCLKIYFCLVVFSYA---RYLFLRT 194 Pneumocystis murina B123
WGS:AATM:SJAG_03015 156 FLQAESAPSIIMLVLVAGFRIYFILVTISYS---SELVLES 193 Schizosaccharomyces japonicus yFS275
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