Conserved Protein Domain Family
CIA30

?
pfam08547: CIA30 
Complex I intermediate-associated protein 30 (CIA30)
This protein is associated with mitochondrial Complex I intermediate-associated protein 30 (CIA30) in human and mouse. The family is also present in Schizosaccharomyces pombe which does not contain the NADH dehydrogenase component of complex I, or many of the other essential subunits. This means it is possible that this family of protein may not be directly involved in oxidative phosphorylation.
Statistics
?
PSSM-Id: 400728
View PSSM: pfam08547
Aligned: 57 rows
Threshold Bit Score: 120.776
Threshold Setting Gi: 81563474
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
O42636        43 HNFQTPESVADCKLLSDADVG-GSSTAHLDWVpppnaiptvtagdgsdrkpytPipgSYARFHGTISLElptd-rreiSR 120 Neurospora cras...
Q5JM48        35 FNFNSKDELKRWHLYSDSEYG-GLSSASLEITdgga--------------ggdTs--STGLFSGNLSLDmsegstwkiRR 97  Japanese rice
XP_010654390  35 FNFNSKEELKKWHLYSDSEYG-GMSSASLEIMda-----------------gnG---LSGIFSGNLSLDliegskwniRR 93  wine grape
Q5CZW0       107 WEFRGPESLNEWIVSSDQEIG-GRSVAYVSLGknn---------------ttcL-------LYGTLSSTpprd--getRY 161 zebrafish
Q7Q4W4        61 FGFESQPDLDRWVVTTDRDHGeGYSQAALERS---------------------Pa--GFGLFHGTLESRvpkd--griKR 115 Anopheles gambi...
Q9VAI1        92 FDFKAPDVLDKWTVTTDADHGeGKSTATLELSaag----------------agL-------FHGQVNSDhtkd--giiKR 146 fruit fly
Q61FQ3       137 YKFDTSEKLDLWKIGCDSDWKeGFSTCSLVNSdrg----------------taV-------FSGNISTRvlkd--grvER 191 Caenorhabditis ...
Q552K6        26 FSFRQQQKLDKWRIVTDQEVG-GFTTAAFKFNp-------------------sD---QFAEFSGIISKKlptn-nsriKS 81  Dictyostelium d...
CAG13255     106 WEFKGPESLDHWIVSSDHEIG-GKSEVYLKMGk-------------------tG---QSCFLYGNLNSTpprd--getRY 160 spotted green p...
NP_001017153 105 WEFRSLEDLDKWTLSSDQEIG-GKSQVSLKLGr-------------------nN---QTALFYGTLNTEvprd--getRY 159 tropical clawed...
O42636       121 TGYAGFRTldrpptifGRGLWDIDPYAYLAMRVKTDARSYFVNVRTESVv------PLDLHQHRLfVKkPGQ-WETVL-- 191 Neurospora cras...
Q5JM48        98 SGFCGMRSk------kFNGFIDLDAYDTIAMKLRGDGRCYISTIYTENWvnspgqqEDNSWQAFVyLP-QDR-WQIMK-- 167 Japanese rice
XP_010654390  94 GGFCGMRSk------kFDGFIDLESYDTIALKVKGDGRCYISTIYTENWvnspaqqEDNSWQAFVfVP-KDN-WYITK-- 163 wine grape
Q5CZW0       162 SGYCSMRSkppkasfdRKKHYDWSSFNTLHLRIRGDGRPWMINVSAETYfs---hqRDDIYSYFLyTR-GGPyWQDVK-- 235 zebrafish
Q7Q4W4       116 AGYANIKSlrvrksfkRDAFYDWSQYNTLVLKVRGDGRSYLINLTAEGYyd---ilWNDIYHYVLyTR-GGPhWQVAK-- 189 Anopheles gambi...
Q9VAI1       147 TGYANIRTkrvrksfkRETTYDWTQYNMLVMKVRGDGRSYLINLHTEGYfd---lmWNDIYHYVLyTR-GGPhWQIAK-- 220 fruit fly
Q61FQ3       192 AGWASMKLedrktfnrKKFLSKWRNFSHLLLKVRGDGRSYKIMLHSPLSmd---ftWGDSFSHPLhTH-GGPyWQYEK-- 265 Caenorhabditis ...
Q552K6        82 TGYAGVFGk------iDLSDYDLNTFNRISVRVKSDKRTYSIALLKSc-------eKQTMYKSIFaTT-PNQ-WETVE-- 144 Dictyostelium d...
CAG13255     161 SGYCSMRSkqpqssfnRKKHYDWSPFNTLHLRVRGDGRPWMINIATETYfs---hqKDDIYCYFLyTR-GGPyWQEVK-- 234 spotted green p...
NP_001017153 160 SGYCTMKSktplgafnRKLHYDWSNFNTLYLRVRGDGRPWMVNIKSDSYfs---qqRDDLYNYFIyTQ-GGPyWQDIKcr 235 tropical clawed...
O42636       192 --------------IKWNDFVRTNHGKVIEPQTGMLRQKVLSIGFSTT--------DR--KAGPYELCV 236 Neurospora crassa OR74A
Q5JM48       168 --------------IPLDSYLPTWRGNVIEAKMEMNPARVVGMSLSVNaeg--gvpGAktGPGDFRLEV 220 Japanese rice
XP_010654390 164 --------------IPLAHYLPTWRGNVIDAEIEMNPSRIVGMSLSVNsgggvpgaTT--GPGDFKLEI 216 wine grape
Q5CZW0       236 --------------IPFSKFFLSSRGRIQDSQHPLWLDKINTIGFTLG--------DK--ADGPFQLEI 280 zebrafish
Q7Q4W4       190 --------------IPFSKFFLASKGRVQDQQGPVPLNRITNVGFSVGs------rGG--HEGSFRLEF 236 Anopheles gambiae str. PEST
Q9VAI1       221 --------------IPFSKFFLSSKGRVQDRQGAIPLNRVTHFGFSVA--------AKkgMDGPFGLEI 267 fruit fly
Q61FQ3       266 --------------IPFSKFFHTVAGRIQDRQYRVNLEDTSSIGIVLM--------DR--IDGDFKLEI 310 Caenorhabditis briggsae
Q552K6       145 --------------VPLNEFFKVHKGVVEMDLSKIETKGIDSIGFVQT--------DK--AEGEFNLKI 189 Dictyostelium discoideum AX4
CAG13255     235 --------------IPFSKFFLTSRGRVQDDQHPLWLDKVNTVGLTLG--------DK--TDGPFQLEI 279 spotted green pufferfish
NP_001017153 236 envyislsscclwqIPFSKFFLSSRGRIQDNQHPLWTDKITAVGFTLG--------DK--ANGPFQLEI 294 tropical clawed frog
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap