Conserved Protein Domain Family
OapA_N

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pfam08525: OapA_N 
Opacity-associated protein A N-terminal motif
This family includes the Haemophilus influenzae opacity-associated protein. This protein is required for efficient nasopharyngeal mucosal colonisation, and its expression is associated with a distinctive transparent colony phenotype. OapA is thought to be a secreted protein, and its expression exhibits high-frequency phase variation. This motif occurs at the N-terminus of these proteins. It contains a conserved histidine followed by a run of hydrophobic residues.
Statistics
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PSSM-Id: 400709
View PSSM: pfam08525
Aligned: 46 rows
Threshold Bit Score: 27.7536
Threshold Setting Gi: 386925657
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q65V97              204 VMQKLPRKHRRLAIALICVVILLLALlwlkPS 235 [Mannheimia] succiniciproducens MBEL55E
utah:Sant_3490      211 WMRPLPLMHRRWLLIIALLVAIALLW----PY 238 Sodalis praecaptivus
WP_015869870         66 WMAPLPAFHRRWLTLICAVLLMALLW----PI 93  Edwardsiella ictaluri
Q6D140               73 WMEPLPLLHRRWILIAIAVLLIVLLW----PY 100 Pectobacterium atrosepticum
WP_013319292         78 WMEPLPYFHRRCILILLCLLLLVLLW----PV 105 Dickeya dadantii
goetting:EBL_c35560  56 LMDPLPLAHRRGIFAGVLLILLGLLL----Pa 83  Shimwellia blattae DSM 4481 = NBRC 105725
Q6LUS0                5 kLTKLPRMHQILIALISAAVVMLILL----PM 32  Photobacterium profundum
Q9KU93                4 LFNRLPWLHRVLITAFSAIIVFAIFFl---PN 32  Vibrio cholerae
WP_014204489          4 IFARLPWIHRALIALFSALIVVALFFl---PN 32  Vibrio furnissii
Q87LY7                4 IFVRLPLLHKVLIGFFSALIIIALFFl---PD 32  Vibrio parahaemolyticus
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