5QST


Conserved Protein Domain Family
STAG

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pfam08514: STAG 
STAG domain
STAG domain proteins are subunits of cohesin complex - a protein complex required for sister chromatid cohesion in eukaryotes. The STAG domain is present in Schizosaccharomyces pombe mitotic cohesin Psc3, and the meiosis specific cohesin Rec11. Many organisms express a meiosis-specific STAG protein, for example, mice and humans have a meiosis specific variant called STAG3, although budding yeast does not have a meiosis specific version.
Statistics
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PSSM-Id: 400698
View PSSM: pfam08514
Aligned: 105 rows
Threshold Bit Score: 79.534
Threshold Setting Gi: 328872810
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5QST_A         79 GDYPLTMPGPQWKKFRSNFCEFIGVLIRQC-QYSIIY--DEYMMDTVISLLTGLS-----DSQVRAFRHTSTLAAMKLMT 150 
Q54QR0        107 QHYPLGNKRS--KILIENFNQFWSELVEKC-KKSIIF--DNYLLDMVALWLHELS-----FAAKRGIRHVATQAAIQITS 176  Dictyostelium...
EGG21177      259 stFPIGGKKA--KGLHNLFIEFFRAIYAKC-QTSIFFehEAYLLNMVIPWTNKLG-----MFKVRGVRYASTLAAIQLAN 330  Cavenderia fa...
XP_001415613  151 gDDPLAKRSRDFKGFRENFLDFIDKCIRDAsEGGELY--DGTLFATLAEIVSTCA-----GSKARPLRMAATMMGLQMIS 223  Ostreococcus ...
Q01FV9        149 gedPLAKRSQDFKGFRENFMEFTDKLIKDTaEGEELF--DGRLYASVAEIVTTCA-----QCKARPMRAAATMMGLQIIT 221  Ostreococcus ...
XP_002978204   72 VEDFVTSKQKDLRGFKDNLTLFWDTFVLEC-QNGPLF--DEQLMEMCINFVTALSwqvkkNTPPRHFRHVSTLIGLQLAT 148  Selaginella m...
XP_009408240  158 vedHVNSKQKELKSFKENLASFWDNLVLEC-QNGPLF--DKVLFEKCMDFVIALS-----CTPPRVYRQVASLVGLQLVT 229  wild Malaysia...
Q60D95        140 vedNYNTKQKDLKNFKENLVSFWDTLVHEC-QNGPLF--DGSLFQKIKDYVVALS-----CTPPRVYRQVASLVGLQLVT 211  Japanese rice
XP_003521521  150 VEDYQNSKKKEIKNFKENLESFWDNLVREC-QHGPLF--DQVLFDKCMDYIIALS-----CTPPRVYRQVASLMGLSLVT 221  soybean
Q19555        184 ADYPLVHGGS-LKKVRANLHNFIHTLIIRT-KASMLF--DSNLMDGFVQLLTGMA-----DSQVRAFRHTATFCAMKITS 254  Caenorhabditi...
5QST_A        151 ALVNVALNLSIHQDNTQRQYEAERNKmigKR-AN-----ERLE 187 
Q54QR0        177 SLISICNDLRKDLNVTTRQLAGETK--------Ns----SRQK 207  Dictyostelium discoideum AX4
EGG21177      331 TLIKLWAQIKQDLTLTRQRLAKENK--------Es----ESFE 361  Cavenderia fasciculata
XP_001415613  224 SLITVVNNLQKARDLKQNQVDIELKK---KK-SGg----EVVK 258  Ostreococcus lucimarinus CCE9901
Q01FV9        222 SLISVVNSLQSTRDLKQNQLDNETKK---KNgVDa----EIVK 257  Ostreococcus tauri
XP_002978204  149 SFVTVAKTLSQSRETKQRQLIAEEKK---KR-KDa----ARIE 183  Selaginella moellendorffii
XP_009408240  230 SFINIAKILSGQRETTQRQLNAEKKK----Q-NEg----PRLE 263  wild Malaysian banana
Q60D95        212 SLISVAKTLSGQRETTQRQLNAEKKK----Q-TDg----PIVE 245  Japanese rice
XP_003521521  222 SYITIANMLRAQRETTQRQLEAEKKK----R-TEg----PRVD 255  soybean
Q19555        255 ALVDVTIELTQSKEKTSKQIEAEKAK---LK--NnsagnEKYE 292  Caenorhabditis elegans
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