Conserved Protein Domain Family
MYT1

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pfam08474: MYT1 
Myelin transcription factor 1
This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells.
Statistics
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PSSM-Id: 400668
View PSSM: pfam08474
Aligned: 23 rows
Threshold Bit Score: 271.61
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5TZG3         665 YKNNVPTSTPRSNLAKELEKYSKASFDYSNtYENQphAYGKRSLIPKSHG-RDTSPKGY-------------Dakryckt 730  zebrafish
Q9QX27         463 FR-SQAITSPRASASKEQEKFGKVPFDYAS-FDAQ--VFGKRPLLQTGQGq-KAPP--Fpeskhfsnpvkfsng------ 529  Norway rat
XP_009295274   622 YRTNAMPATPRANLAKELEKYSKVSFDYAS-FDVQ--VFGKRMLAPKMPTs-ETSPKAFksilipkapspshs------- 690  zebrafish
XP_017161401   647 YRPNMAPSTPRANLAKELEKYSKVSFDYAS-FDAQ--VFGKRTLAPKMTTs-ETSPKAFktkpsfpksssp--------- 713  guppy
14_pfamImport    1 YRPNMAPSTPRANLAKELEKYSKVSFDYAS-FDAQ--VFGKRTLAPKMPTs-ETSPKAFkskrepraaslscIskpsfpk 76  
XP_015220441   624 YRPNVLPTTPRANLAKELEKYSKVSFDYAS-FDVQ--VFGKRVLAPKIQTs-ETSPKAFkskpfpkasspshs------- 692  spotted gar
XP_007246910   660 YRPNVLPATPRANLAKELEKYSKVSFDYAS-FDVQ--VFGKRMLAPKMPTs-ETSPKAFkssspsqslsgg--------- 726  Mexican tetra
TNM86579       203 FRPNTVTTTPRANLAKELEKYSKVSFDYAS-FDVQ--VFGKRTLIPKTPSsTETSPKAFksksfpkasspsq-------- 271  Takifugu bim...
XP_015209284   429 YRFAQPVTTLQASIAKDLDKYGKVRFDYAS-FDAQ--VFGKRTAAPAAQDq-EASH--Fs------------Dsslqyas 490  spotted gar
XP_014344442   602 YRLAQPVTVARASLSKEQEKLWKAPFDYAS-FDAQ--VFGKRTAAPAVQEr-DTPQhveskhspnpvact---------- 667  coelacanth
Q5TZG3         731 sspassttssyapssssslscgggggggggggggssasstcskSSFDYTHDMEAAH--MAATAILNLSTRCREMPQSLAA 808  zebrafish
Q9QX27         530 -----------------------------lpsagahtqstvraSSYGHGQYSEDTHi-AAAAAILNLSTRCREATDILSN 579  Norway rat
XP_009295274   691 -----------------------------lsggytkssssstsSGYDYTHDAEAAH--MAATAILNLSTRCWERPENLST 739  zebrafish
XP_017161401   714 -------------------------------tlslhaygksatLPYDYSHDAEAAH--MAATAILNLSTRCWEKPENLSI 760  guppy
14_pfamImport   77 sssps---------------------------lslhgygksssLAYDYAHDAEAAH--MAATAILNLSTRCWEKPENLST 127 
XP_015220441   693 -----------------------------msssyvkstsssssSGYDYSHDAEAAH--MAATAILNLSTRCWEMPENLST 741  spotted gar
XP_007246910   727 ---------------------------------yakssssstssgYDYSHDAEAAH--MAATAILNLSTRCWERPENLST 771  Mexican tetra
TNM86579       272 -------------------------------sasggfsknatsSTYDYSQDAEAAH--MAATAILNLSTRCWERPESLCS 318  Takifugu bim...
XP_015209284   491 pltsss------------------------rmtvpqgqspcnsSTYSYNPDSDEAHaaAAAAAILNLSTRYRGTANGVSA 546  spotted gar
XP_014344442   668 -----------------------------vslssgpapspchsGSYSYSHNAEDAH--MAAAAILNLSTRCKEAPENLST 716  coelacanth
Q5TZG3         809 --------KGPell-----aqsPDDrDGDDSRALDVGRVGGMGEGs-----GGTVLTPLQPMSPQRQALL---NSHCYQ- 866  zebrafish
Q9QX27         580 --------KPQslr------akGAEiEVDENGTLDLSMKKNRILDksipptSSHTTIATPSSSPFKASSLl-vNAAFYQ- 643  Norway rat
XP_009295274   740 --------RPPdqa------gkDMDiEVDENGTLDLSMKKP-KRE--------GVRSPDPSSSSSSSSQHhgvTSPHSS- 795  zebrafish
XP_017161401   761 --------KPQt---------kEMDiEVDENGTLDLSMKKPIKREgsvsgtSPGVRSPDPSSSSSSSFHHs-gNSGMTSp 822  guppy
14_pfamImport  128 --------KPQnkvahhffiffPSDcSADE--TLQATAGEMRGDSs-----GCAFSTPLLSSHSFFFLHQ------LCM- 185 
XP_015220441   742 --------KQQdlt------skNMDiEVDENGTLDLSMKKHMKREgslscvSPGVRSPDQSQNQSSSASSsamTSPQSS- 806  spotted gar
XP_007246910   772 --------KIQeqp------skEMDiEVDENGTLDLSMKKPKMEG---------VRSPDPSSSSSSFSQQhgvTSPNST- 827  Mexican tetra
TNM86579       319 vsrepcskESDi--------------EVDENGTLDLSMKKTKREG---------LQASEPPSSSSSSSQL---TGATLS- 371  Takifugu bim...
XP_015209284   547 --------RPQals------tkDVLiEVDENGTLDLSMKKNRDRVkappvvPLGIALPTPESSPSKSGSIr-vTPAFYQ- 610  spotted gar
XP_014344442   717 --------KPQdls-------knTTiEVDENGTLDLSMKKNRNQDqatpvtTISSSVSASDSSPIKPSSIl-vTAAFYQ- 779  coelacanth
Q5TZG3         867 --MSTA-DCWDLPVDYTKIKRLDDDHKE--------------DDLDPFQDLLEDQQYSGEVSLPSPKHKYAPC 922  zebrafish
Q9QX27         644 --ALCDqEGWNVPINYSKSHGKTEEEKE--------------KDPVNSLENLEEKKFAGEASIPSPKPKLHTR 700  Norway rat
XP_009295274   796 --HTYKqEEWEGPLDYTKSNRQKEEEPEeveytthsyassdgEDDDGTQEGAEDRTYPGEVTTSSYKVKFQPk 866  zebrafish
XP_017161401   823 nlHTYKqEDWEGPLDFTKPNRQREEETDemehtgqsyvssdpEDCDMMQDCLEDRKYPGEVTTPSFKVKFQPk 895  guppy
14_pfamImport  186 --NISSgEDWEGPLDYTKPNRQREEEMDe--------------DCDMMQDCLEGRKYPGEVTTPSFKVKFQP- 241 
XP_015220441   807 --HTYKqEDWEGPIDYTKPNRQREEDMEevepashsfassepEDCEMIQESMEERKYPGEVTTSSFKVKYQSK 877  spotted gar
XP_007246910   828 --HTYKvEEWEGPLDYTKTSRQKEEEPEeveytihshtssdgEDDDIMQESLEDRKYPGEVTTSSFKVKLQpk 898  Mexican tetra
TNM86579       372 --QGHSqPEWEEPLDFTTQTGVKEEDHEeveyaa--psytssDAEEEDQDNLEDRKYPGEVTTSSFKVKFQAK 440  Takifugu bimaculatus
XP_015209284   611 --ALCEqEGWDTPLNYSKAHIIRDKE-----------------KDEVENEVQEERKYPGDVTIPSPKTKVFSR 664  spotted gar
XP_014344442   780 --ALCEqEGWDMPINYSKTNMKKDESKEk-------------EEAESTAENLEERKYAGDVATPSPKTKLPSR 837  coelacanth
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