3EBB


Conserved Protein Domain Family
PUL

?
pfam08324: PUL 
PUL domain
The PUL (PLAP, Ufd3p and Lub1p) domain is a novel alpha-helical Ub-associated domain. It directly binds to Cdc48, a chaperone-like AAA ATPase that collects ubiquitylated substrates.
Statistics
?
PSSM-Id: 400564
View PSSM: pfam08324
Aligned: 182 rows
Threshold Bit Score: 61.1973
Threshold Setting Gi: 406702114
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3EBB_A        45 PKKEAVTFDQ-ANPTQILGKLKELng-------taPEEKKLTEDDLILLEKILSLIcnsssekp----tvqqlqilWKAI 112
XP_002504496 545 PMRTPVAFET-AKYDGILRKLSEFgaeeg-aagdvAAACNGGDppgas-----------------------siaalAAYL 599 Micromonas commoda
XP_003059881 485 PTTTCLLFDTsLNLDGILKKIAEF-----------AAELATAAQRVEGLRECAAAAasktpps------ttaaaalLDAS 547 Micromonas pusi...
4_pfamImport   2 PVAGYNTFET-TKISKLMSTLRQFndkmk----etgeATALIDSQLIALEQIVHTVqdtafyhsst-faalemtalGDVL 75 
EGR28845     484 TVSNLNYYEQ-MNIEGMKKKFNEInlilk------dtdhYLNDKQLFSLNFMLDMLqktnmyhnsk-lsqpqlevfTLKL 555 Ichthyophthiriu...
EGT34984     597 GLS--------GKGEKAVAKLKELne--------kQDAFQLSTDQINCLEELFHLAttsny----------ssdvaQSAF 650 Caenorhabditis ...
5_pfamImport   2 GLT--------GKGEKAVAKLREFne--------kQDAFQLNPDQLNCLEELFLLPassny----------ssdlaQSAL 55 
EFA81212     228 mNYKAVLFEK-GDIEPVATKLTEFvknv------paidFEEYQKKIQTIQPILKSNdtniaipidlikyfgklieiENLT 300 Heterostelium a...
Q54CK2       217 lnSKSVLFEK-SDVEAVFNKLKEFankefkgkeneQLLITQYEKESNQLKQIMKSVdvdtpis------ietlkyfDGLL 289 Dictyostelium d...
XP_003285270 224 lnYKPVLFEK-SDVDAVFIKLASFaneefk---gisekIKEFEINSPKLQQIIKSTneniivp------ielckylEQLL 293 Dictyostelium p...
3EBB_A       113 ----NCPEDIVFPALDILRLSIKHPSVNENFCnek----egaQFSSHLINLlNPKGKpa------------nQLLALRTF 172
XP_002504496 600 e---SWPVDKLFPLLDLCRMAALRgdaa-----------gvsREVASAMAAaCARSVaeapr------lpanLLTAGRLF 659 Micromonas commoda
XP_003059881 548 a---AWPKEKLFPLLDVARMLVLVPGACDAAT-------------SGAFAAaACRALesggdga--pappgnVLTAGRLF 609 Micromonas pusi...
4_pfamImport  76 d---KWPAKFAFPTLDLLRLVVVHPQGPSALGe---------VGLDTLVTKvLSLGLqtapkegddaipvatRMLSLRVL 143
EGR28845     556 l---KWPQEHILPVLDLFRIFALHPQSDSLFTgvdsglnyftILIGGLGSLne-----------------igKGLIMKTL 615 Ichthyophthiriu...
EGT34984     651 dtalQWPVEHLAPVLDFFRVALTHESLNSYFCtgergqdlvmKIIAILVSdpad---------------mvlKVMVCRCI 715 Caenorhabditis ...
5_pfamImport  56 etalQWPVEHMTPVLDFFRIALMHESLNSYFCtnergvelvgRLIAILVSdpnd---------------lglKVLVCRCI 120
EFA81212     301 n---QLPETNIFPVLELIRFLMLKKQSFEYFTnts------npFISIFINRiLISNLsk-----------ssELIAYRLI 360 Heterostelium a...
Q54CK2       290 s---TFSDDHQFPLLEILRMLLLKNQSNQYYTnqs------npIISNILLKiQSKKLsk-----------psELLSFRVI 349 Dictyostelium d...
XP_003285270 294 k---SFSEPHQFPLLEILRMLLLKDQPNKYFTdls------neTISNLMKSiLKKKLsk-----------asELLSYRVI 353 Dictyostelium p...
3EBB_A       173 CNCFVGQAGQKLXXs-------------QRESLXSHAIELKSGS----NK-NIHIALATLALNYSVCFhkdhnI--EGKA 232
XP_002504496 660 CNAFRHEVARDAFVl-------------RASEILDGLAAAASp----dAKtPARLALATAVLNVSTRVh---vSdaSLAE 719 Micromonas commoda
XP_003059881 610 ANAFKHGETRDAFLp-------------FGQALLDGLAPAAAa----dAKpPARLALATAILNLASFAs----DipAAAD 668 Micromonas pusi...
4_pfamImport 144 ANMFLHDAPRKAMLa-------------HKTEVLGKLPSFQAf----hHK-LVALSLSTVLLNFARVQaa--sPgsLTAD 203
EGR28845     616 CNLFSQTNGKYGMFq-------------HCRFLIEGIKYLRNs----qNQ-NLRNCLVCFFYNVSAEIvf-nqN--YKNE 674 Ichthyophthiriu...
EGT34984     716 GNAFAHPAGRSLFA----------------SYELSTLAPLVIRQllneKQ-ILQMSAATALANWSLAL--------LKQS 770 Caenorhabditis ...
5_pfamImport 121 GNAFSHQAGRNLFA----------------STELSTLAPLVVRQvvheKP-VLQISATTTLANWSLAL--------LKES 175
EFA81212     361 ANCFSSKQGIDYLLksh--------ldaTIECTTKGLHs--------nDK-VLKRAVSTVAYNLSIFLn---pK--QHDD 418 Heterostelium a...
Q54CK2       350 NNCFFSKSGINYLFngngndnnndnlniVIESTIDALHs--------mDK-ILKRAVSTLAYNLSIHLsi-dnS--NHQE 417 Dictyostelium d...
XP_003285270 354 NNCFSSKSGIAYLFsdnn-------indTFECVIDGLHs--------kDK-ILKRAVSTIAYNCSIYLt----S--NYNE 411 Dictyostelium p...
3EBB_A       233 QCLSLISTILEVV---------------QDLEATFRLLVALGTLIsdds----navqLAKSLGVDSQIKKYSSvse---- 289
XP_002504496 720 CAPRAVSVGAELLlsc----------paEEDDARFRTLVALAQIAadggaeckslakDLGLGDVAEALRVSGGs------ 783 Micromonas commoda
XP_003059881 669 LAPACVAVGSQLLyas----------paADVDARFRALVALGTAAttagaeakklaiDLGVLDVATALAAAESa------ 732 Micromonas pusi...
4_pfamImport 204 DQVVVVSLAADLLngay-------tvqeLGDDTILRSLVAIGTLAlsg------dakAKEAAGVHVAIFTAAKasea--- 267
EGR28845     675 NILAFLEELIQVFqt------------eNNPDNILRILISFGNFVi--------------------kYENVSKqvlqkvd 722 Ichthyophthiriu...
EGT34984     771 ETVEQLGPKEDLLralitgieavdsfgfVSEEALSRLLQTIVTIMwgds----svirLAKNRNMAAIAARLKDatq---- 842 Caenorhabditis ...
5_pfamImport 176 ERVEQLGPKEDLLrailsgl--ensnttLCEEAVIRLLQAIVTVMwgda----svirLAKNRNVTSIAARLKDiit---- 245
EFA81212     419 QIISLVSAIQHTLdsn---------plsEDPEIDFRLLMALGTLVy-------------cSDSATDIVSSLELnydky-- 474 Heterostelium a...
Q54CK2       418 QAISLLGAIEHILsesd--------fsnEDPEISFRLLMALGTLIy-------------cNDDLVEILKTLDFdfnkyl- 475 Dictyostelium d...
XP_003285270 412 QNLSLLTAVSHVLseid--------lstEDPEIVFRLLMTVGTLVy-------------cNDESLDILSTLEFdynkyl- 469 Dictyostelium p...
3EBB_A       290 ---------paKVSECCR 298
XP_002504496 784 ----------eRVRDAAG 791 Micromonas commoda
XP_003059881 733 ----------gKVKDAAA 740 Micromonas pusilla CCMP1545
4_pfamImport 268 --------tspAVQECLA 277
EGR28845     723 fagkliqfqdqKIqqclt 740 Ichthyophthirius multifiliis
EGT34984     843 ---------neTTKSMAR 851 Caenorhabditis brenneri
5_pfamImport 246 ---------deTGKSIAR 254
EFA81212     475 ------nqsveKNQNLIK 486 Heterostelium album PN500
Q54CK2       476 ------nskelKISQLIK 487 Dictyostelium discoideum AX4
XP_003285270 470 ------kspedKIKKLIK 481 Dictyostelium purpureum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap