Conserved Protein Domain Family
PIG-X

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pfam08320: PIG-X 
PIG-X / PBN1
Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.
Statistics
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PSSM-Id: 400561
View PSSM: pfam08320
Aligned: 97 rows
Threshold Bit Score: 111.286
Threshold Setting Gi: 403167009
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDN04722      55 PTGLHPTLQISIp----rSSLSEPpprappDSKCSLHTYLTLPSSLFADKYQLSttDPLFlqshnllS---LRAIAGETD 127 Histoplasma cap...
XP_005028144   9 QEGFHRDLLVKLdlgetgEWA----------GGCTVVARSHLPPGIYVDPYELAslQQYN-------Lt-kAVLIPDVVD 70  mallard
EHA97837      17 KDGFHRDLLIKVkfgestEDL----------QTCRLLIKQSIPTGLFVDPYELAsfQEKN-------It-eAVMVSENFN 78  naked mole-rat
XP_002109521  68 lEGFHRDLITKInfrsevKSNLTSf-----SDQCSLLLVERLPTGIYVDLDQVAemERLL-------Kd-iSVISSDRID 134 Trichoplax adha...
EEN55339      75 NHGFHRDVVTEVtlpvamVTPP---------MSCRLLLVETVPAGMYVDLHQVTfrTD-F-------Gg-pQVLALSDID 136 Florida lancelet
NP_001104495  48 KDGFHRDLLIKVkfgesiEDL----------QTCRLLIKHYIPPGLFVDPYELAslRERN-------Lt-eAVMLSESFN 109 house mouse
EHH16882      17 KDGFHRDLLIKVkfgesiEDL----------QTCRLLIKQDIPAGLFVDPYELAslRER--------NiteAVMVSENFD 78  Rhesus monkey
XP_003763745 113 KDGFHRDLLTRVklgtnvENS----------QTCNVLIKYHLPSGLYVDPYELAslQEHN-------Vt-eAMIIQDSVD 174 Tasmanian devil
XP_003209051  34 KEGFHRELLVKMelngtgQWT----------EGCTVAARTHLPRGVYVDPYELAslQQNN-------Vt-kAVLIPDDVD 95  turkey
XP_005050804  74 KEGFHRDLLVKVelg-------------edaGGCAVAAQMRLPPGIYVDPYELAtlQQHN-------Lt-kAVLFPDVTD 132 collared flycat...
EDN04722     128 LEAPDWVTDRWgsSLLLelatPlsrpsrkhkttyvngnhnDDnDDYDEDDWQITIPLHLRYLHP-S--PSGYRNISVPWP 204 Histoplasma cap...
XP_005028144  71 VEAPEYSATGL--VVLL----Y------------------LErDPRCSHCFRGVLPVHVRYHRPa--gDGEAALVALKSP 124 mallard
EHA97837      79 IETPSYLSKES--EVLI----Y------------------ARqDARCADCFQAFLPVHYRYHRPh--sEDAETLIVVGNP 132 naked mole-rat
XP_002109521 135 VEKPAHLSTEH--LLLV----Ya-----------------RInPITDVRSTKVSLPIHLRYHLP-QddWYGYTEVVMPRP 190 Trichoplax adha...
EEN55339     137 VEQAAHQSSHH--RLLL----Ys-----------------PLqQNPKGFTWRVTLPVHLRYHRWaGegEDTSATVRLEGP 193 Florida lancelet
NP_001104495 110 IEAPNYLSNES--AVLI----Y------------------ARqDAQCIDCFQAFLPVHYRYHRPh--kKDGDTLIVVNNP 163 house mouse
EHH16882      79 IEAPNYLSKES--EVLI----Y------------------ARqDSQCVDCFQAFLPVHYRYHRPh--sHDGETSIVVNHP 132 Rhesus monkey
XP_003763745 175 LEAPDYLSEEL--DVFV----Y------------------AKsDSQCSECFRTILPVHCRYHQPk--eKEEKTFVVVKNP 228 Tasmanian devil
XP_003209051  96 VEAPEYSATDL--TVLL----Y------------------LQpDPHCWHCFRTALPVHGRYHRPa--eNSEDVLVVLKSA 149 turkey
XP_005050804 133 VEAPEYLARDL--VLLL----F------------------LErEARCPRCFRAALPVHARYHRPa--rGTGEALLVLESP 186 collared flycat...
EDN04722     205 VV-FWAC--APEDggegetaggGKTMGINPFDRVGLgwdglfapgtlFYQLHPDTAASatgvdahalveqrglmvEKIQV 281 Histoplasma cap...
XP_005028144 125 EV-LVCCcdDHLSte-----swKPAEVEAPCSGKRDyp-------cqWYSAAHKPAYEe----------------lTLQV 175 mallard
EHA97837     133 DL-LMSCdqEFPVls-----cwAQSEVAAPCALKSKnv-------cqWSCLKYQPIHKn----------------vTLHV 183 naked mole-rat
XP_002109521 191 MLiLIHCdkELPEf-------qCQPKYTAPCSNSNKss-------cvWNLLYDNENEDsg-------------neIILKV 243 Trichoplax adha...
EEN55339     194 DV-LMHCegDRPVttp----ceESRLFPAPCDAESRgv-------clWQLLKGKAEP------------------LLFQV 243 Florida lancelet
NP_001104495 164 DL-LMYCdqEFPIlk-----cwAQSEVAAPCALKSEei-------cqWKSMQYKSILKn----------------lTVQV 214 house mouse
EHH16882     133 DL-LMFCdqAGSR-----------GMIRFRFDSFDK----------------------------------------TIEF 160 Rhesus monkey
XP_003763745 229 EL-LVSCynDFPSln-----cwKESDMEAPCSVRNKhi-------cqWSKVKYKSVNQn----------------vTLQV 279 Tasmanian devil
XP_003209051 150 EI-LVCCcdEHLLpe-----cwQPAEVEFPCSGNKDhl-------cqWYNATHQPEYEe----------------lILQI 200 turkey
XP_005050804 187 EV-LLCCchSHLSae-----cwEPAEVDTPCSSDNSsp-------cqWHRTKHRPAYEg----------------sMLRV 237 collared flycat...
EDN04722     282 PVLKIGdggglseDVHSIETVTLIVVCFGFLWVFRSL 318 Histoplasma capsulatum NAm1
XP_005028144 176 PVGLKQ-------HSALVCVVTLLATVFCSSLILAAV 205 mallard
EHA97837     184 PVGLSI-------HSSLVCSVTLLITILCSTSILVAV 213 naked mole-rat
XP_002109521 244 PVGIVK-------HGVLVSIGTIISAIAGTIILIIAI 273 Trichoplax adhaerens
EEN55339     244 PIGQQS-------HAVLVITGTTAVAALGSLLILVAa 273 Florida lancelet
NP_001104495 215 PVGLTI-------HTSLVCSVTLLITILCSTLILLAV 244 house mouse
EHH16882     161 PILKCW-------AHSKVAAPCALENEDICQWNKMKY 190 Rhesus monkey
XP_003763745 280 PVGLRE-------HCLLVCAMTLLVTVLCSVFILRAV 309 Tasmanian devil
XP_003209051 201 PVGLTQ-------YAFLVCVMTLLATILSSSLILVAV 230 turkey
XP_005050804 238 PVGLRE-------HSSLVCALTLLTTGLCSGLILAAa 267 collared flycatcher
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