6TZX


Conserved Protein Domain Family
tRNA_lig_kinase

?
pfam08303: tRNA_lig_kinase 
Click on image for an interactive view with Cn3D
tRNA ligase kinase domain
This domain is found in fungal tRNA ligases and has kinase activity. tRNA ligases are enzymes required for the splicing of precursor tRNA molecules containing introns. This family contains a P-loop motif.
Statistics
?
PSSM-Id: 400549
View PSSM: pfam08303
Aligned: 9 rows
Threshold Bit Score: 226.132
Threshold Setting Gi: 19924244
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6TZX_A  14 IFVPIATIGCGKTTVFNTLNNLFPQ-WTHIQNNNI-SKK-AKLKICDLTLLAL----EDDDQSVVLFDRNNSASRERRQI 86  Candida albicans SC5314
Q6BT50 397 VLIPISTIGCGKTTVFQTILNLFPN-WAHVQNDNI-ANNsTKNKLVVQCLTEL----ARSETSLVFCDRNNHQKRERQQL 470 Debaryomyces hansenii
Q6CK12 389 LLVTIATIGCGKSTVSLTLNELFPEsWGLVVNDNI-TS--NKTDYIKSALQLF-----KDGKQFVLADKNNHQFRERAAV 460 Kluyveromyces lactis
Q754H3 394 IFIPVATVGCGKTTVALALKNIFGEsWGHIQNDNI-VTK-DKSKLMRDALEFL----QKDTSRAVIVDRNNHMPFERKQL 467 Eremothecium gossypii
Q6FJW3 389 LIIPVAVIGCGKTTTAMTINNIYPEsWGHVQNDNI-TGK-DNSLLMKRSLELL----AKPGIKCVVVDRNNHQARERKEL 462 [Candida] glabrata
P09880 393 LIFPISVIGCGKTTTSQTLVNLFPDsWGHIQNDDI-TGK-DKSQLMKKSLELL----SKKEIKCVIVDRNNHQFRERKQL 466 Saccharomyces cerevis...
Q6C923 432 VILPIATIGCGKTTVSLALHSLFG--WHHIQSDNI-KGTgVGRKMVQEGCRIIrdgdKEKKSQVIILDRNNSNLIERKQL 508 Yarrowia lipolytica
Q10313 387 LLVPIATIGCGKTTVAKILEKLFG--WPVVQNDNLpSGKgGPKRFAKAIIEEF-----RNGHSVVFADRNNHISNMRSTL 459 Schizosaccharomyces p...
Q7RZ64 420 ILVPIATIGCGKTTVGLALTHLFG--WGHVQNDNI-TGKaRPPRFTKALLDIL-----DEGVPAVYADRNNAQKHERKQL 491 Neurospora crassa
6TZX_A  87 FTTIDQKRDEHLDDTVDLKYIAINFIPEDlSEEELWDITYNRVIQRGDNHQSIKSQL-DENLVESVMKGFIQRYQPINTS 165 Candida albicans SC5314
Q6BT50 471 FDQFLSLKDMYLSADIGLRFIAINFVDVSlDKQELFDVTYDRISKRGDNHQSIKFNT-DAKLANQVMNGFIKRFQRVDIN 549 Debaryomyces hansenii
Q6CK12 461 FEWINQYRDSYIPYNCNLQVIALCFVDEV--SPEMRALTIDRVMKRGDNHQSIKSESdDQQKVLKIMQGFMNRFQPFLPS 538 Kluyveromyces lactis
Q754H3 468 FEWLEKMKENYIPYNSAVKVVCLSFLTYK-DVESVREITKSRVAERGDNHQSIKALSePEKAIM-ILDGFLKRFRAVNDQ 545 Eremothecium gossypii
Q6FJW3 463 FDWIDEYKEDYLPYDTNIKVICLSFTKRD-DLENVREITTNRVFARGDDHQSIKLSKyGEKKVMGIMSGFIKRFQPVNED 541 [Candida] glabrata
P09880 467 FEWLNELKEDYLVYDTNIKVIGVSFAPYD-KLSEIRDITLQRVIKRGNNHQSIKWDElGEKKVVGIMNGFLKRYQPVNLD 545 Saccharomyces cerevis...
Q6C923 509 FDEFDRLKCNPI-------FVCMSFVDGDdQVRE--KLARDRVLKRGENHQSIKVETmGMTRVDQIMRDRCKKMQGVNKA 579 Yarrowia lipolytica
Q10313 460 QTDILALID-------GVRFVALPFKH----TPEVPEFVQNRVLQRGDRHQSIKVSE-GVDKVKAIMNTFYKQYKPFDPA 527 Schizosaccharomyces p...
Q7RZ64 492 ITDVKIQHA-------RARLVALHFVHND--LEKVREVCRDRVFARGDNHQTIQAAS-DMNKVRGIMEGFINRFEPCDPE 561 Neurospora crassa
6TZX_A 166 -RSPDDQFDHVIHLKLS 181 Candida albicans SC5314
Q6BT50 550 -QEPDNQFDLVINMKIS 565 Debaryomyces hansenii
Q6CK12 539 -KDPDNKFDFHIQLEVG 554 Kluyveromyces lactis
Q754H3 546 -RSPDNMFDKIIQLKVL 561 Eremothecium gossypii
Q6FJW3 542 -RMPDIMFDHVIDLTVT 557 [Candida] glabrata
P09880 546 -KSPDNMFDLMIELDFG 561 Saccharomyces cerevisiae S288C
Q6C923 580 -KEPDSRFDLVIECAVA 595 Yarrowia lipolytica
Q10313 528 gNKHDANYDDIIELDPL 544 Schizosaccharomyces pombe 972h-
Q7RZ64 562 -QKPDSEFDDIIDLDPs 577 Neurospora crassa
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap