Conserved Protein Domain Family
DPM3

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pfam08285: DPM3 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
This family corresponds to subunit 3 of dolichol-phosphate mannosyltransferase, an enzyme which generates mannosyl donors for glycosylphosphatidylinositols, N-glycan and protein O- and C-mannosylation. DPM3 is an integral membrane protein and plays a role in stabilizing the dolichol-phosphate mannosyl transferase complex.
Statistics
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PSSM-Id: 400538
View PSSM: pfam08285
Aligned: 91 rows
Threshold Bit Score: 62.9445
Threshold Setting Gi: 158276551
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHY52938       1 MGRAAQTISLALLVTSAYLLLALPLLtedspipsilpTKIQVEIIPVLPFWAIISLGAYLLGRLGLGVLRFNDTEDAYRE 80  Exophiala derma...
XP_003060323   2 arRLFTLGAPVVAFLAVWVYLLRIGL-----------PPAQHSVVLLLPLWALVSFALYSLAVIGWSLAHFPTCAKDAEI 70  Micromonas pusi...
EFN55694       1 MLRIFRLSAVGLLLLAAWAALLQQTT-----------EEPARTWVLLAPLLALVVFGAYLATALLYGVATFRTVPEEAEL 69  Chlorella varia...
XP_006364061   1 MKHIVKILALLLAVTAVWIGLLQTST-------------IPESYTWLLPLYLIVSLGCYGLLMVGIGLMNFPTCPQEALF 67  potato
XP_009401151   1 MKHILKIMALLVAVAGIWISLLETSV-------------VPRSYTWLLPVYLVVSLGCYGLLMVGVGLMLFPTCPQEASL 67  wild Malaysian ...
Q8LEQ4         1 MKHIVKILSLLVAISAFWIGLLQAAI-------------IPRSHTWLLPIYFVVSLGCYGLLMVGVGLMQFPTCPQEAVL 67  thale cress
O94633         1 MQRIHKVILYYVSLTILYRVTYLFDL-----------EEPWSTLRPYTPYLFILAFGSYLGITLLYNVATTNDKPEAYVD 69  Schizosaccharom...
XP_002172096   1 MQRIHKILVYFILMSIFKNSLYLIDM-----------EEPWASIRPWTSIILLALYGVKLGFELLYNVANTHNKPEAYVD 69  Schizosaccharom...
A0DWS0         1 MSRGTNLFVAFSISGIVWIVTLfl------------sTGYVNEVAKSMPTYALILYFSYALFKVGGDLARLKDYPEEAQS 68  Paramecium tetr...
Q23W00         1 MVRKTKFIVLFLLFGLVWSFVVFSGLls--------kNKPLDTIAKALPGYLLMVFGCYSLYSIGYDLWILKEYPEDYQS 72  Tetrahymena the...
EHY52938      81 LMGQIEQAKKNLDKRDV 97  Exophiala dermatitidis NIH/UT8656
XP_003060323  71 LQREMGVAQRELCAKGI 87  Micromonas pusilla CCMP1545
EFN55694      70 LQKDIARARADLARRGI 86  Chlorella variabilis
XP_006364061  68 LQQDIVEAREFLKKKGV 84  potato
XP_009401151  68 LQKDIIEAKEFLKSRGV 84  wild Malaysian banana
Q8LEQ4        68 LQKDIAEAKDFFKHKGV 84  thale cress
O94633        70 LVKDIKEAQDALRSKGM 86  Schizosaccharomyces pombe 972h-
XP_002172096  70 LVKDIKEAQDALRAKGM 86  Schizosaccharomyces japonicus yFS275
A0DWS0        69 LQKEVEEAKRFYKEKGL 85  Paramecium tetraurelia
Q23W00        73 LLKEIDEAKAFYKKNGV 89  Tetrahymena thermophila SB210
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