3VZ9,2VE7


Conserved Protein Domain Family
Spindle_Spc25

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pfam08234: Spindle_Spc25 
Chromosome segregation protein Spc25
This is a family of chromosome segregation proteins. It contains Spc25, which is a conserved eukaryotic kinetochore protein involved in cell division. In fungi the Spc25 protein is a subunit of the Nuf2-Ndc80 complex, and in vertebrates it forms part of the Ndc80 complex.
Statistics
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PSSM-Id: 400508
View PSSM: pfam08234
Aligned: 136 rows
Threshold Bit Score: 36.4219
Threshold Setting Gi: 74608166
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3VZ9_B        31 EQLQFIFRHIDHKDPD-KPYMFTLSINEqGD--YEVTSCTPPLDC--ISEFQLKVRETNNFSAFIANIRKAF 97 
CDS41996     167 NNVQVVMRGCCEDDYD-LLSYVILRFNA-DStpMELIKCNPP--VtdVEKLVEHFNKAGDFRSFLLVLRDRF 234 Echinococcus multilocul...
EEQ82584     166 NKIKVLFNKFCKDETF--ECYVVLDLSD-G---YNIIDIYPK--VinIERYSTNLKDKTRFFELIQDVRKIF 229 Nosema ceranae BRL01
Q8SU30       179 NVIKVVFSRICPEDSV--ECFVTLDLSA-DGp---VVDLFPR--MygLERANSLFREHNNFHDFLRVIRSGF 242 Encephalitozoon cuniculi
XP_008075515 164 NMLKIEFFNFDETDLG---GYIVMDFKD-DTe--sVTEVWPC--VvsLEKINLVLNISDDFYDFLKRVRGIF 227 Vavraia culicis subsp. ...
OWR42030     137 QVIFVQFFTESKKDNEnYSVRLIRNIKN-GK--YELLSVNPK--LkcLKELQKEMCDTNNVPGVLCALRQAF 203 Danaus plexippus plexippus
XP_001705813 159 NSIIVIFWGLNPADES-QQYSFRLITRE-DGe---IIIEDPTIEIanLDLFLSDAKITGNIPLLIRRIRLSF 225 Giardia lamblia ATCC 50803
Q4UAV3       190 GSMKISFSRLIGSNPY-TICMIILKLED-ER--FIGISSDPPIKd--FSKLVSELNNGLDFGSFLCLVRKSF 255 Theileria annulata
CAX64353     147 DKIVIEFSNIQDSEPQ-KKYRATLVLKN-GI--YEVIETNPRINk--FEDFVDSLNKGLPFTTFCCLLRRSF 212 Plasmodium falciparum 3D7
XP_001614238 147 DKIAIEFSNIQPGDPQ-KKYRATVALHN-GT--YEAIETAPRLNk--FDDYVNGLNKGLPFTTFCCLLRKSF 212 malaria parasite P. vivax
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