Conserved Protein Domain Family
RepA1_leader

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pfam08048: RepA1_leader 
Tap RepA1 leader peptide
This family consists of the RepA1 leader peptides. The frequency of replication of IncFII plasmid NR1 during the cell division cycle is regulated by the control of the synthesis of the plasmid-specific replication initiation protein (RepA1). When RepA1 is synthesized, it binds to the plasmid replication origin (ori) and effects the assembly of a replication complex composed of host proteins that mediate the replication of the plasmid. The tap gene encodes a 24-amino acids protein. The translation of tap is required for translation of repA.
Statistics
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PSSM-Id: 116658
View PSSM: pfam08048
Aligned: 5 rows
Threshold Bit Score: 26.7421
Threshold Setting Gi: 81416006
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q65AF5    1 MLRKLQYPFLCHLLLPCNISAGRCD 25  Yersinia pestis
Q9ZEW6    1 MLRKLQAQFLCHWLLLCNISAVGCD 25  Klebsiella pneumoniae
Q7ARH6    1 MFRKVQYL-LRLLLLPCNISAGRCD 24  Yersinia pestis
Q7DAR1    1 MLRKFQYLFLWHLLLPCIVSAGRSD 25  Salmonella enterica subsp. enterica serovar Typhimurium
OVD76651  1 MLGKVQDFFLCSLLLR-IVSAGWCD 24  Escherichia coli
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