Conserved Protein Domain Family
Fucokinase

?
pfam07959: Fucokinase 
L-fucokinase
In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated by L-fucokinase to form L-fucose-L-phosphate, which is then further converted to GDP-L-fucose in the reaction catalyzed by GDP-L-fucose pyrophosphorylase.
Statistics
?
PSSM-Id: 400353
View PSSM: pfam07959
Aligned: 45 rows
Threshold Bit Score: 309.575
Threshold Setting Gi: 217402669
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
CBJ29017      126 SGGDSQRSPTQCVCGKAWSALNScgdsg-----sgrcNTPMDLL---LEHLSRLFSGGSSgSLePGTLVVTACDVMLlvp 197  Ectocarpus si...
XP_003290380   36 nGGIHQHAPLVNLCTKSFSMLPLnnkfv-----gdspVYPIDILlsnLNVILPHA---------QPGFMVCSTESLI--- 98   Dictyostelium...
2_pfamImport    1 ------RDFPWSSCSRAFCWLPLes-----------aDQSVHAPlccLDLLLDRLGRQVCpGS-PPGVWVCSTDMILhip 62  
5_pfamImport    1 ------RDFPWSSCSRAFCWVPApe----------epNCRVQAPvccVDLLLDRLSTNICpGS-PPGVWVCSTDMILnip 63  
XP_003227902   90 lilhmgRDFSFDDCSRAFTCLPLed-----------pSAPVEALtcnLDNLLATLTCQICkGS-PPGVWVCSTDMLLtvp 157  green anole
XP_004175035   89 lilhmgRDFSFDDCGRAFTCLPAed-----------pGAPAEALvcnLDSLLGTMTHRLCvGS-PPGVWVCSTDMLLtvp 156  zebra finch
Q7TMC8         91 lilhmgRDFPFDDCGRAFTCLPVen-----------pQAPVEALvcnLDCLLDIMTHRLGpGS-PPGVWVCSTDMLLsvp 158  house mouse
EEC42659       94 AGGESSRCPTQMILGKAWTSLPTmssvgspgvatcrlQTPVHVW---LRICERLFRGIP-----NGSIVVLAADTLLrlp 165  Phaeodactylum...
XP_003417207   91 lilhmgRDFPFDDCGRAFICLPVen-----------pQAPVEAVvcnLDCLLDIMTHRLGpGS-PPGVWVCSTDMLLsvp 158  African savan...
XP_023208122   91 lilhtgRDFPWSSCSRAFCWLPEek-----------pGQKVQAPvcvLDLLLDRLSTQICpGS-PPGVWVCSTDMIL--- 155  southern plat...
CBJ29017      198 pevaatadwSF--------DQQSGaagGVAGLAIAADAAkYASNHGVYCLDGGg--------gGGGQeSHGITGVRKYLQ 261  Ectocarpus si...
XP_003290380   99 ---------FLdlndknlnSPSSWqkpGVSVITMDVGPD-YYTNHGVCRLNEK-------------------DEILEIAY 149  Dictyostelium...
2_pfamImport   63 pdfvlswegFS----------------GVRVLALPGDVS-YALNHGVYLSDQQ-------------------GRVRDIVY 106 
5_pfamImport   64 pdftlswngFS----------------GVRVLALPGDAS-YAADHGVYLSDPQ-------------------GQVRDIIY 107 
XP_003227902  158 svpkidwhgFT----------------GARVVAMPGSFS-YAKQHGVYLADGQ-------------------GFVQDIIY 201  green anole
XP_004175035  157 stpginwdgFQ----------------GVRVIAVPGSPA-YARNHGVYLTNEQ-------------------GLVRDIIY 200  zebra finch
Q7TMC8        159 pnpgiswdgFR----------------GARVIAFPGSLA-YALNHGVYLTDSQ-------------------GLVLDIYY 202  house mouse
EEC42659      166 d--------------skfaIDWEAhadTVFGLAVPAPLA-TASNHGVFVLPPMrtnavpgasdQSSEpVIQVEPCHDVLQ 230  Phaeodactylum...
XP_003417207  159 pnpgiswdgFR----------------GARVIALPGSSA-YARNHGIYLSDSQ-------------------GFVLDIYY 202  African savan...
XP_023208122  156 ---------SVpth--cvlSWEGFs--GVRVLAVPGDVS-YAADHGVYLSDSQ-------------------GRVRDIIY 202  southern plat...
CBJ29017      262 KPSREEAEASGAFLNPggmaapknesgnpnhdpsanPEVAIDSgVVVFSGAATRALTSLA------HSEtfkgctsrg-- 333  Ectocarpus si...
XP_003290380  150 KRSAEYLSNNGFISKE--------------------DKASIYTgLVFFCQKTTEKLLYLHntp-plDSCtylgvds---- 204  Dictyostelium...
2_pfamImport  107 KGREEQLV--PAVMPD--------------------GKVPLVSgPVFFSSLVSEKLLLTHvtp-plDGCtylglds---- 159 
5_pfamImport  108 RGTREQIQ--QAVMHD--------------------GKVPLVSgPVFFSRSISEKLLQAHvtp-plDGCtylglds---- 160 
XP_003227902  202 QGSEDQIQ--RCVGSD--------------------GKVPLVSgIVFFSSEAAEQLLATHvip-plNACtylglds---- 254  green anole
XP_004175035  201 KGTEAQIQ--QCAGPD--------------------GTVPLVCgIVFFSSDAAEQLLATHvvp-plDACtymglds---- 253  zebra finch
Q7TMC8        203 QGTKAEIQ--RCVGPD--------------------GLVPLVSgVVFFSVETAEHLLATHvsp-plDACtymglds---- 255  house mouse
EEC42659      231 KPSQSTLQA-HCQFKQng-----------------qACAWIDTgVIVFLPTTATILRRLAfddellSRCtastlqsmqnr 292  Phaeodactylum...
XP_003417207  203 QGTEAEIQ--RCARPD--------------------GRVPLVSgIVFFSVETAERLLATHvsp-plDACtymglds---- 255  African savan...
XP_023208122  203 RGTREEIQ--RALMPD--------------------GKVPLVSgPVFFCRSVSEKLLQTHvsp-plDGCtylgvds---- 255  southern plat...
CBJ29017      334 ------------vaggasalrLELYSDLLLALRTGGGTGESAegtldayleacGHVLPPDHDV----SKARREIWDALSG 397  Ectocarpus si...
XP_003290380  205 ---------------gsqllkFGVFPDILCAMTKHETLESYLn---------qPCFPGSNKKLv---EGARKIVWKTFRD 257  Dictyostelium...
2_pfamImport  160 ---------------gapplqISLFLDVLKCLCSDVTQDRFVsedr---tgcsSPVGPQGATV----RRGREELWRILRG 217 
5_pfamImport  161 ---------------gapplqVSLFLDLLKCLCSDLTQDQFVtedr---agcsSPVGPEGASV----RRSRAELWRLLRG 218 
XP_003227902  255 ---------------gappiqLSLFFDILLSMARGVSEEAFVnglgp-rtggsGDNTQSEAAL----WSARAVLWKTLHT 314  green anole
XP_004175035  254 ---------------gappiqLSLFFDIVLCMAGGMTEEDFV-------------KGGGDASV----RNARSVLWTALRG 301  zebra finch
Q7TMC8        256 ---------------gaqpvqLSLFFDILLCMARNMSRENFLag-------rpPELGQGDMDVasylKGARAQLWRELRD 313  house mouse
EEC42659      293 hladgdspesalikaqdasfrFDLYTDLLQALPMVASMDDRLdngk---vtqgPSYAVLRESF----RSCR--------- 356  Phaeodactylum...
XP_003417207  256 ---------------garpvqLSLFFDIVLSMARNVSKEDFLvg-------rpPEMGQGDVGIaaylQGARAELWRELRD 313  African savan...
XP_023208122  256 ---------------gapplqISLFLDLLKCLCSDLTQDQFVnegr---agcsPTDGLQGATV----RAGRAELWRILRG 313  southern plat...
CBJ29017      398 FP--LGALLLQGATFVHLGTTPELMEMLTLRLPEFIEPy---GLTARASSVVGAACsV-En----------DPPAVVVNS 461  Ectocarpus si...
XP_003290380  258 IE--LHSIKIK-GNYYYFKNPMDFLNFIHNNGKYQISRkmhsFIATKS-----------------------PCNGVVINS 311  Dictyostelium...
2_pfamImport  218 TP--LTVAYVPGGCYDYLTLSGKQHVE---------------RLSRDWTDRN-----V-Lshiqk--ergvDPGARIINS 272 
5_pfamImport  219 ETctLLYSYVPGGCYDYLTLSGKHHVQ---------------RLCCDWMNRN-----T-LshiqfqresavRDGGRVING 277 
XP_003227902  315 MP--LIMAYVPDGSYDYMTSSASDHIH---------------HLTTSVGNAHGGSFsK-VahshveepgllEEGCSVTNS 376  green anole
XP_004175035  302 FP--LSMACIPNASYDYMTASASDHIR---------------SLTLLPSSASHLRFcK-TahshvdqpcllEDGSSVTNC 363  zebra finch
Q7TMC8        314 QP--LTMVYVPDGGYSYMTTDATEFLH---------------RLTMPGVAVA-----Q-IvhsqveepqllEATCSVVSC 370  house mouse
EEC42659      357 ----LSVMTIPSGRFLHLGTTRELLDFYTHGCHSNTE-----PLTASMSPPQALCReF-Gtslalt-------rrleafT 419  Phaeodactylum...
XP_003417207  314 QP--LTMAYVPDGSYSYMTSLASELLH---------------SLTVPSTPRA-----Q-TvhsqveelellEPGSSVVSC 370  African savan...
XP_023208122  314 AP--LSLVYVPGGCYDYLTLSGKQHVD---------------RLTSDWTVGNTLSHiQvNen-------llSEGARIINS 369  southern plat...
CBJ29017      462 SLHGAGVVAGGAVVEHCYFDr-DGWE-VGAGSLISGIRSLEEDChl--rLRGGMCLQQTDLDRASPEEta--srFVVSLF 535  Ectocarpus si...
XP_003290380  312 ILLGNGKCSDTSIIYSSVLS--GNWS-VGEDSIVFGAKSLSAny----hIKDRMIVNEIRLKPIKMKHssnetpRALLVL 384  Dictyostelium...
2_pfamImport  273 VLEEDVAVATGAVVQHCHLK--GPLK-VPAGCLLSGLSSAASQClrqldLGADIIVQGHHIQLGDLKL------RVYTVM 343 
5_pfamImport  278 VLEGDIAVATGAVVQHCHLQ--GPLE-VPSGCLLSGLPLMTSQClrqlqLADDIIIQGHRIEVGGLKL------SVYTVT 348 
XP_003227902  377 LLEGAVFVGPGTAIQHCCLK--GPLQ-IHSGCLLTGLDGDSSEAlrghhLK-DVVIQGHAVRLKGLSC------KVFTLS 446  green anole
XP_004175035  364 VLEGAVQLAAGSVIQHCHLQ--GPLV-IGPGCLLSGLDVDSSPAlrgcpLR-DVVLQGHHVRLRDLPC------RVFTLT 433  zebra finch
Q7TMC8        371 LLEGPVHLGPRSVLQHCHLR--GPIR-IGAGCFVSGLDTAHSEAlhgleLH-DVILQGHHVRLHGSLS------RVFTLA 440  house mouse
EEC42659      420 LVGPYGQIDPSAIIMHSSIQdsLSMEsVGSLPMV---------------IPDNTIVQQVRRVPQDEADtc---aCTLVVL 481  Phaeodactylum...
XP_003417207  371 VLEGPVWLGPGSVLQHCHLR--GPIH-ISTGCFLSGLDIAQSEAlhgmeLR-DLILQGHHMRLHGSLG------RVFTLT 440  African savan...
XP_023208122  370 ILDGGVTVATRAVVQHCHLQ--GPLD-VPSGCLLSGVDVSASAClrrlaLSSDIIIQGHRIQLGELKL------NMYTVT 440  southern plat...
CBJ29017      536 GARDDIKAHYSADRA----RVCGATWEAFFGYTGATAEDVWGGIEEGDR-KLWSARLFPVLTR 593  Ectocarpus siliculosus
XP_003290380  385 GIQDDLNLYFTDPNA----TIANRTWEEFLKTSGIAPEELWSKGLPR---ILRTARLFPIIvd 440  Dictyostelium purpureum
2_pfamImport  344 GAQDPLEASFGDRGA----SFLNQSWSRFCSRTGIQPEEVWLKPEQR---SLLEARLFPVFSP 399 
5_pfamImport  349 GAQDVLEASSEDSGA----SFLNHGWSLFFSRTGIQSEELWVRGERR---SLLAARLFPVLHP 404 
XP_003227902  447 GRHNRWESLAE-EDG----TYLNARWSDLFLRTGIRREDLWSGDVLPGRgCLLNAHLFPVLHA 504  green anole
XP_004175035  434 GRLDDWQSPVE--KA----TYLNVPWAEFFQRTGLREGDLWDAEMPRGSrCLLSARLFPVLHA 490  zebra finch
Q7TMC8        441 GRLDSWERQGA---G----MYLNMSWNEFFKKTGIRDWDLWDPDTPPSDrCLLTARLFPVLHP 496  house mouse
EEC42659      482 GVDDKIKSLDG---------LYGRPLQDFMSWAGLSESDLWDEEADHK--MVWNARLHPSikp 533  Phaeodactylum tricornutum CCAP...
XP_003417207  441 GRLDNWE-----RQGtgtyLNMP--WSEFFQKTGIRDWDLWDPDTPPTErCLLSARLFPVFHP 496  African savanna elephant
XP_023208122  441 GAHDDLQVPFNDSGA----SFLNQTWTVFFSSSGIKPEELWVKGEHC---SLLEARLFPVLHP 496  southern platyfish
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap