Conserved Protein Domain Family
Nairovirus_M

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pfam07948: Nairovirus_M 
Nairovirus M polyprotein-like
The sequences in this family are similar to the Dugbe virus M polyprotein precursor, which includes glycoproteins G1 and G2. Both are thought to be inserted in the membrane of the Golgi complex of the infected host cell, and G1 is known to have a role in infection of vertebrate hosts.
Statistics
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PSSM-Id: 285223
Aligned: 2 rows
Threshold Bit Score: 1101.6
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8JSZ3  241 PTNRSKRNLKMEIILTlsqglkkyyGKILRLLQLTLEEDTEGLLEWCKRNlGLDCDDTFFQKRIEEFF--ITGEGHFNEV 318  Crimean-Congo hemor...
Q02004   99 VLDRQSRASSVRELLN---------TKFLMLLGFIPKGEVNHLENACNRE-GKNCTELILKERIARFFseTEKESCYNTY 168  Dugbe virus (isolat...
Q8JSZ3  319 LQFRTPGTLSTTESTP---AGLPTAEPFKSyFAKGFLSIDSGYYSAKCYSgtsnSGLQLINITRHSTRIVDTP--GPKIT 393  Crimean-Congo hemor...
Q02004  169 LEKHLRSVSPEVSLTPyrvLGLREDILLKE-IDRRIIRFETDSQRVTCLS----ASLLKPDVFIREQRIDAKPsnGPKIV 243  Dugbe virus (isolat...
Q8JSZ3  394 NLKTINCINLKASIFKEHREVEINVLLPQVAVNLSNCHVVIKSHVCDYSLDIDGAVRLPHIYHE-----GVFIPGTYKIV 468  Crimean-Congo hemor...
Q02004  244 PVDSVACMNLEANVDVRSNKLVIQSLMTTVKISLKNCKVVVNSRQCIHQQTGSGVIKVPKFEKQqggtwSSYIAGVYTAT 323  Dugbe virus (isolat...
Q8JSZ3  469 IDKKNKLNDRCTLFTDCVIKGREVRKGQSVLRQYKTEIRIGKASTGSRRLLS-EEPSDDCISRTQLLRTETAEIHGDNYG 547  Crimean-Congo hemor...
Q02004  324 IDLLDENNQNCKLFTECIVKGRELVKGQSELKSFNIEVLLPRVMKTRRKLLAvTDGSTECNSGTQLIEGKSIEVHKQDIG 403  Dugbe virus (isolat...
Q8JSZ3  548 GPGDKITICNGSTIVDQRLGSELGCYTINRVRSFKLCENSATGKNCEIDSVPVKCRQGYCLRITQEGRGHVKLSRGSEVV 627  Crimean-Congo hemor...
Q02004  404 GPGKKLTICNGTSVLDVPLDEGHGCYTINVITSKRACRPKNSKLQCSIDKELKPCDSGKCLSISQKGAGHIKVSRGKTIL 483  Dugbe virus (isolat...
Q8JSZ3  628 LDACDTSCEIMIPKGTGDILVDCSGGQQHFLKDNLIDLGCPKIPLLGKMAIYICRMSNHPKTTMAFLFWFSFGYVITCIL 707  Crimean-Congo hemor...
Q02004  484 ITECKEHCQIPVPTGKGDIMVDCSGGRQHYLEVNIVDIHCPNTKFLGGIMLYFCRMSSRPTVALLLGIWIGCGYILTCIF 563  Dugbe virus (isolat...
Q8JSZ3  708 CKAIFYLLIIVGTLGKRLKQYRELKPQTCTICETTPVNAIDAEMHDLNCSYNICPYCASRLTSDGLARHVIQCPKRKEKV 787  Crimean-Congo hemor...
Q02004  564 SFLLYHLILFFANCIKQCRKKGERLGEICVKCEQQTVNLMDQELHDLNCNFNLCPYCCNRMSDEGMSRHVGKCPKRLERL 643  Dugbe virus (isolat...
Q8JSZ3  788 EETELYLNLERIpWVVRKLLQVSESTGVALKRSSWLIVLLVLFTVSLSPVQSAPIGQGKTieayrAREGYTSICLFVLGS 867  Crimean-Congo hemor...
Q02004  644 NEIELYLTTSEC-LCLSVCYQLLISVGIFLKRTTWLVVLLVLLGLAISPVQGAPTEVSNV-----KQDGDYSICYFIFGC 717  Dugbe virus (isolat...
Q8JSZ3  868 ILFIVSCLMKGLVDSVG 884  Crimean-Congo hemorrhagic fever virus strain IbAr10200
Q02004  718 LVTAALLLKVKRTNSNG 734  Dugbe virus (isolate ArD44313)
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