Conserved Protein Domain Family
TMEM43

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pfam07787: TMEM43 
Transmembrane protein 43
This entry represents the transmembrane protein 43 family of proteins, which may function as tetraspanin-like membrane organizers.
Statistics
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PSSM-Id: 400234
View PSSM: pfam07787
Aligned: 63 rows
Threshold Bit Score: 133.962
Threshold Setting Gi: 156088401
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A0BGH4           128 WVQKSREEGSKKN-KRTVYYYESEWSSKIEGSYPNH-------ENRrEdLTVQEQELTAENVYIGAYKLTDYlKSKAVDY 199 Paramecium ...
XP_001298636      95 WTELEHSETINNV-THYSYTYHKMWTHRPINSLFFHnpt---yhNPs--VEIIPERSFHNQMKAGTFFLSDSlSYSGSTD 168 Trichomonas...
XP_004030327     135 WQEYKHSRRISNNyEEIYYTHNIDWRNEFIDSQYFHeni--ghQNYkQdWLYDSKVIYAPNVFFGTFKLSEKqKEMCENS 212 Ichthyophth...
A0BRM1           155 WIRKEETDGVGNN-KKIKVFFVPEWSAIKQGSYENF-------ENNeSdWTVKKKSKYAKDVYLGAYLLTKFqLKQAKNF 226 Paramecium ...
A0D1A8           105 WVRRSRQEN-----NRTTYYYEQIW------SSTFHadvgdgyFNDqSkWIVQAEDKINENVYVGAYLITKSlAEQTDAN 173 Paramecium ...
A0CU25           143 WVRKSREEN-----KRTVYYYVQEW------SSTFHsdcgdghYNDkSkWIVEQETQVNLNVRIGAYLMSKSlAEQTNAH 211 Paramecium ...
A0DSK3           157 WVRKTKEEN-----NTTVYYYVQEW------NTTFHsdcgeghFNNkNyWIVEQETQINMNVRLGAYLMSKSlAEQTNAK 225 Paramecium ...
A0EH31           123 WVVGEKQK-------------EQQWVDHYVENSFGY-------NNDkSkWILNSETFLNISVKLHQFELPEDmKTQLNTP 182 Paramecium ...
A0BGH2            30 WVKGDQKQ------------YEQKWVDHHVENHFGY-------NNDkSkWVLKAQTFLNQCVKLHQFMLEEDmIKELNTP 90  Paramecium ...
jgi:Cal7507_5568  85 WVEEQSQVSEN---NPPEYTYTQLWLEYPPNSGKFKere--nhKNPt--LKIHSNSQSVQTANIGVYKID-PlQISLPEP 156 Calothrix s...
A0BGH4           200 VQVDSISQQQCEAAkva-------------------fqSRTQQYIFFDGRYIQFRKSENS-------------------- 240 Paramecium ...
XP_001298636     169 TLHPHNQQIVQFQN------------------------SPYAKQFQFAGRGIFYSTYKDGyletllkvgqffdlgsrgys 224 Trichomonas...
XP_004030327     213 EIIRMNQQQY-----------------------------QGHKQIQIIQDYIYFRKIPNQ-------------------- 243 Ichthyophth...
A0BRM1           227 QEIQPSQEWVTACAka--------------------fpKKTQEHTKIKDEYIYFNKVYGN-------------------- 266 Paramecium ...
A0D1A8           174 EIINLTSEHAQNVAkyf-------------------atQRIFQHFDAQGKEMYFQQEKGR-------------------- 214 Paramecium ...
A0CU25           212 ESIPMAANNAQAVSnfy-------------------gfSKGFQNYEANGQYIYFQQNRGT-------------------- 252 Paramecium ...
A0DSK3           226 ESIPMNLHNAQVVAnfy-------------------gyEKGFTNYEANEQYIYFQQNKGA-------------------- 266 Paramecium ...
A0EH31           183 LETVKLNQANVQIFqqr-------------------ykDKGYRRFLLQDDYIYMHQVEDQ-------------------- 223 Paramecium ...
A0BGH2            91 LQNVKFNQANVQIAqqk-------------------ykDSGFSRFLLQDDYIYMHQVDDQ-------------------- 131 Paramecium ...
jgi:Cal7507_5568 157 TEIQLTDSDVVIPKpktktdlilsptflslvgsiprreG----------NYIYIGSG----------------------- 203 Calothrix s...
A0BGH4           241 --QSIGDQRVLFEKVPCN-YAAIVARQHKESFKP---Ylfkdsfsddvnqdyaknpdmlksfnrfhelseeeqplnqidp 314 Paramecium ...
XP_001298636     225 ewCEPGDRRVWFEYWAPE-QVTVIGKAMNGLILPvslY------------------------------------------ 261 Trichomonas...
XP_004030327     244 --NSCGDFRVQFTKCTCG-ESTIIAKQHQNTFEV---Fhpgdynegdthfgd-----------------------aqccs 294 Ichthyophth...
A0BRM1           267 --LTVGDQRIKFQKVKCG-DATIVSQQKGNTFEP---Yslhvneskllndyddkgsdhsiy------vgqdlsqileekd 334 Paramecium ...
A0D1A8           215 --LLNNDLRVSFRAARIG-PTTVVSQQQNNTFTP---Yiihdkyeqtlnqdgenlenp-----------nplgilscccc 277 Paramecium ...
A0CU25           253 --VSMNDLRVSFDAARTG-PTTVVSQQYNDTFTP---Fvihdkfeqtlardenle-----------------dmsltctt 309 Paramecium ...
A0DSK3           267 --ITMNDLRVSFNASKTG-PTTVITYQQNDTFTP---Fvfqdkfnqtlardqnfenl--------------dnvefncan 326 Paramecium ...
A0EH31           224 --IVNGDLRICFKQVICS-DATIVARAIINSLLV---Wqfedtynktvskqnq-------------------------vq 272 Paramecium ...
A0BGH2           132 --IVNGDLRISFKQVICS-DATIVARGDTNRLLV---Wqfedtfnktvardyd-------------------------ah 180 Paramecium ...
jgi:Cal7507_5568 204 --LLAGDVRIHYEGVPQLkNVTVFGKLDKNQIVP---Y------------------------------------------ 236 Calothrix s...
A0BGH4           315 ssevssnifKSyeAPLNYINWYFNRSF-TLDQCFQSQLSKLVRMVWLCR--VGGFFMFLF----------------GFVL 375 Paramecium ...
XP_001298636     262 ---------------DYKIGSAISGFVtTRDAIANNFSIIPTIFKWVMRasISGLILYFLsqniqfnysyfgliiaGIIL 326 Trichomonas...
XP_004030327     295 ccfsicefcRFlnQAVDEINWIKEKHI-SKEEFFNEKLQSQEFKTWLIR--LCGYLLLVF----------------GIFL 355 Ichthyophth...
A0BRM1           335 denalkrqlKHllEPIKYIDWLLEKML-TIHQVFDHKLNESRKLTMAVR--FLGFLLMFF----------------GLML 395 Paramecium ...
A0D1A8           278 ccfcccqlcKAieQPLSELNLLYQAVL-TQQQVFKKLAEEYACLTLCQR--ITGYILMGF----------------GFYL 338 Paramecium ...
A0CU25           310 cccfccklcRAleKPLTQIDWIFEQIM-TQNQVFKKKAEENACLTLAQR--IGGYILMGI----------------GFCL 370 Paramecium ...
A0DSK3           327 cccfickyfRSieKPITEINWIYESIL-TLDQVFQKKADENQCTTTLQR--LGGYTIMGV----------------GFWF 387 Paramecium ...
A0EH31           273 ekelsdtqlpnedKPIKQIYWIFQGLF-TPEECLQKVVNENALLFWVFR--SIGYILIAV----------------GSII 333 Paramecium ...
A0BGH2           181 ertccnlpvpndsKPIKDIYWIFQGLF-TPEECFSKVVNENALLFWVFR--SIGYILIAI----------------GTII 241 Paramecium ...
jgi:Cal7507_5568 237 ---------PY--KNSRIYNVYYGNRD-AAIAEINSQYKANLGFFLLMP--IVGFLLMWIivysyspqptscrltfGIAI 302 Calothrix s...
A0BGH4           376 LFTPITTLLYYIPLLggflSKLTGIVLAFLSGMISMPLTLGTIGIAWLYYRP 427 Paramecium tetraurelia
XP_001298636     327 AQPMISGKYC------------------INKSTGGLLLFSAVVALPNFVFRY 360 Trichomonas vaginalis G3
XP_004030327     356 MLSPIYKLLYWFPFVgkflGTIGSLICLLVGLIVAIPPAIIVIGLAWLFYRk 407 Ichthyophthirius multifiliis
A0BRM1           396 FFSPVVYVISWFPFLgrfmAELSTLLFALASFLISLPLTLITIALAWLRFHP 447 Paramecium tetraurelia
A0D1A8           339 IFYPVTWVVSLVPLIgdflAAITGFAFFLVSFLISIPFSILTIAFAWLFYHP 390 Paramecium tetraurelia
A0CU25           371 IFSPISWLVSWFPLVgnflASITGFIFFLVSFIISIPFSLLTIAFAWLFYHP 422 Paramecium tetraurelia
A0DSK3           388 IFSPITFIVSVLPFIgnflAQIT------VSFTISIPFSILIIAFAWLFYHP 433 Paramecium tetraurelia
A0EH31           334 LLSPVSQLSQLIQS-----DQLSGFGFIIYGLIGAIPINIFSICFCWLYYRP 380 Paramecium tetraurelia
A0BGH2           242 LLSPVSFLTDFIPI-----EKLTGISFFIFGCIAAVPITIFAICFSWVYYRP 288 Paramecium tetraurelia
jgi:Cal7507_5568 303 FISIVAIAVSCITY--------------NYFWVLFISLLLLVVALRWFQRRi 340 Calothrix sp. PCC 7507
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