2HDI,1FEP,6BPN,1BY3,6E4V,1XKW,1XKH,4EPA,5FQ6,1PNZ


Conserved Protein Domain Family
Plug

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pfam07715: Plug 
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TonB-dependent Receptor Plug Domain
The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Statistics
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PSSM-Id: 400180
View PSSM: pfam07715
Aligned: 626 rows
Threshold Bit Score: 37.2487
Threshold Setting Gi: 81740726
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2HDI_A  19 NLKDAPASISV-ITQEDLQRKPVQNLKDVLKE-VPGVQltn--egDNRKGVSIRGLd-------sSYTLILVDGKRVNSr 87   Escherichia coli
Q8F194 131 LQRKSGVVSDA-ISEEAIKKSPDSSAGDVLRR-VTGITl------VGGRFIFVRGLg-------eRYSNTILNDSVIPSp 195  Leptospira interrogans
Q8P5B4  65 EPMLQTSEVASfVTREDMERTGDSSAAVALTR-VTGLSl------SRGKYVYVRGLg-------eRYSSALFNGSPLPSp 130  Xanthomonas campestr...
Q9ABQ5  71 VVRTGSQVVSV-LSAAEIARTGEGNIAGALTR-VTGVTl------VGNGYVYVRGLg-------dRYSLALLNGSPLPSp 135  Caulobacter vibrioides
Q8A7N5  50 REVRSASPLQV-FNKEELKNLQALQVSDAVKH-FAGVTvkdyggiGGLKTVSIRSLg-------aQHTAVSYDGITVSD- 119  Bacteroides thetaiot...
Q8A5Z2  30 PMKDIGVQQTR-FDSLVLKENIALSMADILTF-NSSIFvks-ygrATLSTVSFRGTs-------aSHTQVTWNGMRINN- 98   Bacteroides thetaiot...
Q89H12 102 DVDKVPSAINA-VDANQIKRTGSLNVTDALRDnIAGVNitevtgnPFQPDVEFRGFvaspvtgtpQGLAVYQNGVRINE- 179  Bradyrhizobium japon...
Q8P569  58 DAAQLPYMVQS-ANRAELSRGRSNNLGDLLQRrFVGVDgndvqgsAFQNDLTFHGFrasalpgasQGVSVYLDGVRFNE- 135  Xanthomonas campestr...
Q7M977  36 DISKNP-SLEI-VTQETIRETEAKSVVDALQS-VPGIYtdy-agaRGETKVRLRGFs-------sTRVPLYIDGIPIYV- 103  Wolinella succinogenes
Q8KBM4  41 VTGKSANSSET-VPAAEMEMLDKQNLSEAADL-LPGVTisn-vggRNEGMIYVRGFd-------mRQVPLYLDGVPLYV- 109  Chlorobaculum tepidum
2HDI_A  88 navFRHNDFDLNWIPVDSIERIEVVRgPMSSLYGSDALGGV 128  Escherichia coli
Q8F194 196 --ePDKRIVPLDLFPAGVIKNIRVIK-TASAEDSAEFSGGI 233  Leptospira interrogans
Q8P5B4 131 --ePMQRVVPLDLFPSDVLQSVTVQK-TYSADYPGEFGGGV 168  Xanthomonas campestris pv. campestris
Q9ABQ5 136 --ePLKRVVPLDLFPSRVIASSLVQK-SYSANFPGEFGGGV 173  Caulobacter vibrioides
Q8A7N5 120 ---CQTGQVDIGRFSLNNVDRLSLNNgQSDNIFQPARFFAS 157  Bacteroides thetaiotaomicron
Q8A5Z2  99 ---PMLGMTDFSMIPSYFIDDASLLHgTSSVNMAGGGLGGL 136  Bacteroides thetaiotaomicron
Q89H12 180 ---AFSDAVNWDLIPTAAIRSVTLVTnNPA--FGLNALGGA 215  Bradyrhizobium japonicum
Q8P569 136 ---PFADIVSWDMLPEAAINAVTLMPgSNP-LFGPNTLGGA 172  Xanthomonas campestris pv. campestris
Q7M977 104 ---PYDHNIDLGRFKTYDIGEIDVSKgYVSPMYGANTMGGA 141  Wolinella succinogenes
Q8KBM4 110 ---PYDGYVDPNRFLTMNLSEVSVSKgFTSVLYGPNTLGGA 147  Chlorobaculum tepidum
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