4B87


Conserved Protein Domain Family
DRMBL

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pfam07522: DRMBL 
DNA repair metallo-beta-lactamase
The metallo-beta-lactamase fold contains five sequence motifs. The first four motifs are found in pfam00753 and are common to all metallo-beta-lactamases. The fifth motif appears to be specific to function. This entry represents the fifth motif from metallo-beta-lactamases involved in DNA repair.
Statistics
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PSSM-Id: 400071
View PSSM: pfam07522
Aligned: 30 rows
Threshold Bit Score: 98.4856
Threshold Setting Gi: 121876902
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4B87_A           241 PEINSLITTDMCSSLVHLL-PMM------QIN----FKGLQSHLKKCGGK-YNQILAFRPTG--WTHSNKFTRIADvI-P 305
Q96SD1           239 PEILHHLTTD-RNTQIHAC-RHP------KAEeyfqWSKLPCGITSRNRI-PLHIISIKPSTmwFGERSRKTNVIVrTgE 309 human
Q5QJC2           239 PEILYHITTD-RYTQIHAC-RHP------KDDdyvrGNRLPCGITCQNGT-PLHVISIKPSTmwFGERIKKTNVIVrTgE 309 chicken
Q5RGE5           239 PEILCHVTTN-RATQIHAC-RHP------KDEeffrANRLPCGSTAPDGI-PLNIISIKPSTiwFGERTRKTSVVVkMgS 309 zebrafish
JCVI:AT1G19025.1 230 mvivpEIVSEDPSSRFHIFsGFP------KLY----ERTSAKLAEARSKL-QSEPLIIRPSAqwYVCDDEDDWKSGsIqK 298 thale cress
Q8RZQ7           227 SLIAPEIITEDPSCRFQIL-GFQ------NLY----DKACTKIEEARASL-QPEPLFIRPSTqwYAHCAQSqkps----- 289 Japanese rice
Q8IK95           674 KHILNKITDNKLEAQIHIV-DINysyifpKID----KRKFLNLIDEEIEKeFDSFYYIIPTG--WVKKFSf--------- 737 Plasmodium ...
Q4Q2L8           388 EHLLSVFLVPMASVGYRAVaALA------HADgp-aVMDMEDGLALNLDR-YDQVLMVEPTG--WSKRCVAREVSE---- 453 Leishmania ...
EAY09804         231 FAKPELFSEDPYLTRIHLL-PIQ------ECG----KEKVSLYAASMG---FDSVTAIRPSG--WNGRPFWRCPTFdIyN 294 Trichomonas...
EAX84063         225 YCSESCFTNDPTKTRVYLV-PIM------DCN----SVSASVWAKQNG---YSSVCAIAATG--WSGKAGWKNPQItYqG 288 Trichomonas...
4B87_A           306 Q--------TKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVG 346
Q96SD1           310 S--------------SYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPV 344 human
Q5QJC2           310 S--------------TYRACFSFHSSYSEIMDFLSYIRPVNVYPNVLPV 344 chicken
Q5RGE5           310 S--------------SYRACFSFHSSYLEVKDFLSYICPVNIYPNVIPL 344 zebrafish
JCVI:AT1G19025.1 299 QrkvrfseaVKDEFGLWHVCYSMHSSRAELESAMQLLSPKWVVSTVPSC 347 thale cress
Q8RZQ7           290 -----lteaVLDGCGVWHICFSIHSSRDELEQALELLQPQWVISTTPPC 333 Japanese rice
Q8IK95           738 --------yERNNISIFLIPYSEHSNLDELKNFVKSIKPCNILPTVFYN 778 Plasmodium falciparum 3D7
Q4Q2L8           454 ------------KYTLLRVPYSEHCAFHELLEFVAFVNPARVVPTVSEE 490 Leishmania major
EAY09804         295 E----------IKVTSYDVPYSDHSSPMELTEFVKAVKPAKVIPTTTKN 333 Trichomonas vaginalis G3
EAX84063         289 P----------IKVTLYEVPYSDHSSPQELLNFVKVVKPKKLVSTTSRS 327 Trichomonas vaginalis G3
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