Conserved Protein Domain Family

pfam07494: Reg_prop 
Two component regulator propeller
A large group of two component regulator proteins appear to have the same N-terminal structure of 14 tandem repeats. These repeats show homology to pfam01011 and pfam00400 indicating that they are likely to form a beta-propeller. This family has been built with artificially high cut-offs in order to avoid overlaps with other beta-propeller families. The fourteen repeats are likely to form two propellers; it is not clear if these structures are likely to recruit other proteins or interact with DNA.
PSSM-Id: 400050
View PSSM: pfam07494
Aligned: 659 rows
Threshold Bit Score: 26.8918
Threshold Setting Gi: 1680438310
Created: 21-May-2020
Updated: 7-Aug-2020
Aligned Rows:
Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
3V9F_D        207 SLPGN-DVR--CIYKDTNGNIWIGTSK 230  Bacteroides thetaiotaomicron
Q8EJW5        144 GLTDP-RVT--KLNIVGNT-LWIGTQS 166  Shewanella oneidensis
Q8EJW5        185 TSIEP-YIT--SLANVDNTYLLAGTKG 208  Shewanella oneidensis
Q8ECQ1        465 TLISE-QLTy-SIQKDRN-YLLFGTSK 488  Shewanella oneidensis
Q87RE3        463 QYLPA-KVT--RLYDTEDK-LFIGTDH 485  Vibrio parahaemolyticus
Q9Z5U8          4 ILGKE-TIT--ALAETKYN-LFIGTNS 26   Zymomonas mobilis
Q8A3N1        263 DENNE-AIYcrTLLVYTDNELWIGTES 288  Bacteroides thetaiotaomicron
Q8A1I3         92 LLTTN-SIT--CLVDDNNNHLWIGTSE 115  Bacteroides thetaiotaomicron
Q8AB44        102 LLTNN-EIT--CIAENKNGYLFIGTKK 125  Bacteroides thetaiotaomicron
WP_040963481  210 DEPNRqSSIf-GLQWTGD-RLWLGSES 234  Xanthomonas citri
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