Conserved Protein Domain Family
GRDB

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pfam07355: GRDB 
Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
This family represents a conserved region approximately 350 residues long within the selenoprotein B component of the bacterial glycine, sarcosine and betaine reductase complexes.
Statistics
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PSSM-Id: 429424
Aligned: 59 rows
Threshold Bit Score: 519.388
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Shel_25400   2 TKKVIYYVNQFFGGIGGEDTADFEPEIREGQVGPAVAANGQLK-DAEITHTIICGDNFMGSNTEEALSRILGFLEDKEFD 80 
CCX74221         1 MKKILFYTNQFFGQIGGEDMAYAEPQVFEGMHGSANTFGAPLKdIAEIVATIVCGDNFYAENMETGRAFLLEQIKKYQPD 80 
WP_022278342     4 KIRVVHYINQFYGGYGGEDTASMGIVIKEEPVGPGLALAKNLGeNYEIVATFICGDNYIAENTDEVCRQLIDTVKKYKGQ 83  Dorea
jgi:Anamo_1045   1 mLKAVHYINQFFGQVGGEESADFEPVLQEGPVGPGLLLNEAMK-EVKITHTVICGDNFMASHPEEAVARILKMLEGLKFD 79 
EHM12620         1 -MKAIHYINQFFGQVGGETAADAAPSFPEKLIGCSLMLNGMMP-DVEVTHTIICGDNYVTNHTDEALKEIFAFLDGQEFD 78 
jgi:Tlie_1457    1 mLKAIHYINQFFGQVGGEDAADYRPTFHDELVGCSKMLNEMMD-DVEVTHTIVCGDNYIASNTEEALKEIIDWLKGQEFD 79 
jgi:Hprae_0136   1 MKKAIVYLNQFFGQIGGEDVADHAPEIREEKVGAAMLYNQLL--EAEVTHTVICGDNFMGSKTEEAVETILDFLRDLEFD 78 
jgi:Acear_2273   2 SKKAVHYINQFFGQIGGEEEADYPPSIEEGTVGPANLLDNLL--DAEVTHTVICGDNYMGSNEEDAVETILEALEDIDFD 79 
jgi:Halha_2198   1 MKKAILYLNQFFGQIGGEDQADYEPTLEEGKVGPAMLLDQLLD-NAEVTNTVVCGDNYMGSNEEEAIERILSFLEDKEFD 79 
jgi:Acear_2278   1 MKKAILYLNQFFGQIGGEDKADFAPVIKEGQVGAGMLLNNLLE-DAEVSHTVICGDNFMGSNEEEAVDTILGFLEDKDFD 79 
jgi:Shel_25400  81 LLIAGPAFQAGRYGVACGNVCKAVGEKFGVPTVTSMNVENPGVEMFKKDTYIMDGANAAAKMRKDLKNLVGFANKLLSGE 160
CCX74221        81 LIIAGPAFNAGRFGIACGDVCKTAKEQAGVEAITGLYEENPAVDMFKKDVYILRVAKSAAGIRKAVPLMAGFARKLLTGE 160
WP_022278342    84 LFVAGPGFNAGRYGIGCGAATSAVTRTLKIPAVTALYAENPGTDLYKDQCYILQTENNAAKMRQVVKQVAVFAKRLVEGD 163 Dorea
jgi:Anamo_1045  80 VFLAGPAFNAGRYGVACGTICKAVKEKFGVPVITSMNEENPAVEMFKSNMYIFKGGRRATYMKQDVEKMAAFADKIARGD 159
EHM12620        79 IFFAGPAFMAGRYGVGCGLVCKAVAEKYGVPVITSMNEENPGVSEYRGSAYIFKGGRKATYMKDDLTAMARFAEKIARGE 158
jgi:Tlie_1457   80 IFFAGPAFMAGRYGVGCGTVCKAVKETFGVPVITSMNEENPGVEMFHKDVYIFRGGRKATFMREDLQKMASFAQKIARNE 159
jgi:Hprae_0136  79 IFFAGPAFQAGRYGMACGEIGKAVKEEFDVPVISSMNIENPGVEVFKKDIYIFPGGHSAAKMKDDVTEMTKFGNKILKGE 158
jgi:Acear_2273  80 IFIAGPAFQAGRYGSACGTIGKAVKERFEVPVITCMNEENPGVDMFKKDLHIFPGGASAAKMRDDMKKVADFGNKILNGE 159
jgi:Halha_2198  80 IFFAGPAFQAGRYGNACGAICKAVKEEFDVPVITSMNNENPGVDMYKKDMIIFPGGQSAAKMRDNMKDMADYGNKILNNE 159
jgi:Acear_2278  80 IFFAGPAFQAGRYGNACGVICKAVKEKFGVPVISSMNEENPGVDMFKKDVDILPGGQSAAKMKDDMTKMAELGNKFLAGE 159
jgi:Shel_25400 161 PLQGAEIEGYFPRGIRHEIYLEDKhe--ntAAYRGVQMLIKKIKGEPFQTELVVPVKDVVEPAAPV-NLSEAVIAMITTG 237
CCX74221       161 PIGTPEDEQYYAKGKRVNIFREKN------GAERAVDMLLAKVKGEPYKTELEISTYEKVEPSAPIaDLSKAKIALCTTG 234
WP_022278342   164 FIGDGKKEGYHGSGPEIEIDYTIP------APKRALAMLLKKYHHENFYTEVIMPNHEDIPLPVLDkPLDEIKIAVVTDG 237 Dorea
jgi:Anamo_1045 160 KLLPASMEGYFPRGIRHEVFLEDLglepkcAADRAFDMLLKKLKGEPYETELPIPKQERVPIAPAVkDLRKVKIALVTSG 239
EHM12620       159 PLLPAAEEGYFGRGIRAEIPAAVR------ADDRVIDMLLKKLAGQPFQTELVIPKSDVIPPARPVaDLSKATVALVSSS 232
jgi:Tlie_1457  160 ELLPAEIEGYFPRGIRREIFHPEGi----qAADRAVDMLLKKLKGEPFKTELPIPKREKVPVAPPIkDLSKATIALVGSS 235
jgi:Hprae_0136 159 ELLPAEEEGYYTRGIRHQYFLEDQt----pATERAIEMLLKKIKGEEFTSELPIPELDRVEIAPAIkDLSKAEIALVTSG 234
jgi:Acear_2273 160 ELLSAEEEGYFLRGKRHQVWLEDEt----pAAERAVDMLLKKLNGEEFETELPMPENMGVEIADPIeDLSEAKVALVTSG 235
jgi:Halha_2198 160 ELGSAEEEGYFIRGKRHQVWLEDEi----pAADRAIDMLLKKVNGEEFKSELPMPDMDRVEIAEPIeDLSEVKVALATSG 235
jgi:Acear_2278 160 TGLTAEEKGIYIRGKRHQVWLEDEt----pAADRAMDMLLKKINGEEFKSELPMPKIDKVPIADPIeDLSEATVALATSG 235
jgi:Shel_25400 238 GIVPVDNPDRIQSASATRWGRYNIEGvDKLpn-rASGGYKTIHAGFDPAAADADPNVIMPIDAMRQLEKEGKFARLHNYF 316
CCX74221       235 GMVPMGNPDHMVAATAKFWKEYPVEG-DKL----ESGKWESVHAGFDPVYANNDPNRVAPYDMLKMLEKEGIIGSVYPAL 309
WP_022278342   238 GLVPKGNPDNQVPTNSRYYKIYDTHGvDAL----NAKDYEVSHQGYNNAFVLADPNRLVPVDALMKLKKEGKIGEVYQKF 313 Dorea
jgi:Anamo_1045 240 GIVPKDNPDRIQSCSATKWGAYDISKlDRL----MAPDFKTIHAGYDPEQANKNPNVVLPLDAIRQYQKEGRIGEVDDHY 315
EHM12620       233 GVVPSDNPDRIQSASAQKWGSYEIDGkDCL----PAGEFKTIHAGFDPAAMCAVPDRGVPVDAMRYFEKQGKLGKLFHKY 308
jgi:Tlie_1457  236 GVVPFDNPDRIQTASATKWGKYNIAGlDHL----PKGKFKTIHAGYDPEAICEVPDRGMPVDAMRAYEKEGKIGKLHDYY 311
jgi:Hprae_0136 235 GIVPVDNPDKIQSASATRWGKYEISGmEKLen-rEAEAFKTIHAGFDPAAADADPNVVVPVDAVRQYEKEGKIGKLHEYF 313
jgi:Acear_2273 236 GIVPVGNPDNIQSASATRWGKYDISDlDEFpsreEEEGYRTIHAGYDPAAADAVPDRVVPLDAMRKYEEEDRIGKLHGYF 315
jgi:Halha_2198 236 GIVPVDNPDNIQSASATRWGRYDISGlNQLpn-rDAEGFKTIHAGYDPAAADANPNRVVPVDVMREYEKEGRIGELDNYF 314
jgi:Acear_2278 236 GIVPVDNPDKIQSASATRWGRYDVSGmDKLen-rEAGAFKTIHAGYDPAAANEDPNRVLPLDALRAYEKEGKIGKVDDYF 314
jgi:Shel_25400 317 YSTVGTGTTESEAARMAEEMIPYLKEDGVNAIILGST 353
CCX74221       310 ISTTGNSTSVADSTRMGQEIAERLVSAGVNGVILTST 346
WP_022278342   314 YSTAGVMTPMEMGKKFGEGIAKDMKENGVDAAILTST 350 Dorea
jgi:Anamo_1045 316 YVTVGTGTTQAEAARMGREIAQRLKERNVGAVVLTAT 352
EHM12620       309 YVTVGTGTTQAFAAKFGREIAKELLEAKVDAVILTST 345
jgi:Tlie_1457  312 YVTVGTGTTQAYAAKFGREIAAELKEAGVDGVLLVAT 348
jgi:Hprae_0136 314 YSTVGTGTTQGEAARMGREIAQELQDANVQAVILTST 350
jgi:Acear_2273 316 YTTVGTGTTEAEASRMGAEIAEELLEADVQAVILTST 352
jgi:Halha_2198 315 YSTVGTGTTEAEASRMGQEMVEKMLEDGVQAVILTST 351
jgi:Acear_2278 315 YATVGTGTAEVEAARMGQEMVEEMQRDGVDAVILTSn 351
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