Conserved Protein Domain Family
TMEM126

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pfam07114: TMEM126 
Transmembrane protein 126
This entry includes the transmembrane protein 126 A/B (TMEM126A/B) from animals. Human TMEM126B participates in constructing the membrane arm of mitochondrial respiratory complex I.
Statistics
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PSSM-Id: 399831
View PSSM: pfam07114
Aligned: 35 rows
Threshold Bit Score: 206.712
Threshold Setting Gi: 198412897
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002124594  27 TNIHELIDYKLSQMSKNERGFFNYSLFGLSGFGVVSAIVINSLFRKSLMVYEGAILTS---TVVPVLSSAfnlSAQSALV 103 vase tunicate
XP_024203274  31 PMVIEIIEKKFDYL-RKEMTQNIYQMATFGTTAGFSGIFSNFLFRRCFKVKHDALKTYaslATLPFLSTV---VTDKLFV 106 chimpanzee
XP_002754778  50 PMIIEIIEKKYECL-KKEMMPYIYHMTLIGTAAGCTGIFTNFTFRHTFKVKYDALKTYaslATVPFLSTV---VAHKLLV 125 white-tufted-ea...
XP_002708706  51 PMVIEIIEKKFEYL-RKEKTLNIYGTLTLGTTAGFSGILANFIFRHCFKVKHDALKTYaslTTLPFLSTI---VAYKLLV 126 rabbit
XP_003468564  49 RMIIENIEKKFEYL--RRDKAFLPGPVFFAASASLSGILANFILRHCFKVKHDVLKTYaslTALPFLSTI---VTYKFFV 123 domestic guinea...
EHB18499      23 PMVIKIIEKKFEDL-RKYKTLDLHGIVTLATSSSFSGIVSNFLLRRSLNVKHHALKTYaslIALPFLSTI---VTYKFLV 98  naked mole-rat
XP_004019457  51 PVVIEIIEKKIECL-REEKTLNIHGTLTFGTTAAFSGMLTNFIFRHRLKVTHDVLKTYaslTALPFLSTI---VSYKLLV 126 sheep
XP_006092967  50 PMVIEIIEKKIEYL-RKENALNIRGTLLVGTAAGFSGILANFLFRHCFKVKHDALKTYaslTTLPFLSTL---VTYKLLV 125 little brown bat
XP_542274     51 PMVIEIIEKKFEYL-RREKTLNTYGTVFFGTAASFSGLLANLIFRHCFKVKHDALKTYasvTTLPFLSTV---VAYKFLV 126 dog
2_pfamImport   1 TNIYSLIDHKLEQTSKFDQKFFNYSVYGLSSFGVMSAVLINSSFRRALMVFEGAIFSG---VTIPLLSSVfnlTAQSALT 77 
XP_002124594 104 QTPIVKGTA-CSVCaTVRGGAVQTITTCLVPAGISVGMAAVLAERYKSAEvpsfgFPPDKHFRSFWAKIFKQVFRKASPL 182 vase tunicate
XP_024203274 107 IDALYSDNIsKENC-VFRSSLIGIVCGVFYPSSLAFTKNGRLATKYHTVP-----LPPKGRVLIHWMTLCQTQMKLMAIP 180 chimpanzee
XP_002754778 126 IDALYSDNIsKENC-VFRSSLIGMVCGVLQPNSSAFLKNGRLATKYHTIP-----LPPKGRVLLHWMQLCQTQVKLMAIP 199 white-tufted-ea...
XP_002708706 127 TDALYSGNIsKENC-VLRSSLVGIVCGILYPSSLAFSKNGRLAVRYHTVP-----LPPKGRVLLHWMLLCQTEIKAMVIP 200 rabbit
XP_003468564 124 TDALYSDHIsKENC-VLRSSLVGLVCGVLYPSGLAFSKNGRLAVKYHTVP-----LPPKGRVFLHWLLLCQTQIKAMVIP 197 domestic guinea...
EHB18499      99 IDPLYSGNIsKENC-VARSSLVTMICGVIYPNGLAFSKNGRLAVKYHTVP-----LPQKGRVLLHWLLLCHKNIKAMVIP 172 naked mole-rat
XP_004019457 127 TDALCSGNIsQENC-VLRSSLIGIACGVLYPTALAFSKNGRLAFKYHTVP-----LPPKGRVLLNWLLLCHTEIKAMVIP 200 sheep
XP_006092967 126 TDALYSGNIsVEEC-ALRSSLVGIVCGVLYPTGLAFSKNGRLAVKYHTVP-----LPPKGRVLHHWLMLCQRDIKGMLIP 199 little brown bat
XP_542274    127 TDALYLGNIsQENC-VLRSTLVGIVCGFLYPCGLAFSKNGHLAVKYHTVP-----LPPKGKFLLYWLLLSQREIKGMIIP 200 dog
2_pfamImport  78 QSPMVKGSL-CPVCaTIRGSVIQTVTTCLIPAGMSSAMAAILADRFKSAEvpsfhLPPNKQFRTFWGKIFRQVFRKTYPL 156
XP_002124594 183 IFLQALLGGVVAYRQHQIIEKAKM 206 vase tunicate
XP_024203274 181 LVFQIMFGILNGLHHYAVFEETLE 204 chimpanzee
XP_002754778 200 LVFHIAFGVINGLHYYTVFESTLQ 223 white-tufted-ear marmoset
XP_002708706 201 LVFQTMFGILIGLQHYSLFEKTLA 224 rabbit
XP_003468564 198 IILLTQFGILNGLQQYAIYENTYK 221 domestic guinea pig
EHB18499     173 LVFMTPFGLFGGAQHYEMFKKTHE 196 naked mole-rat
XP_004019457 201 LILQTTFGIFHGLQHYAIFESTLE 224 sheep
XP_006092967 200 LAFQIVFGIYQGIQHYAVFQSTLE 223 little brown bat
XP_542274    201 LVFQTVFGIFNGLQHYAIFESTLQ 224 dog
2_pfamImport 157 IVFQAVLGGYVAYKQYEIVENARE 180
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