Conserved Protein Domain Family
DUF1338

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pfam07063: DUF1338 
Domain of unknown function (DUF1338)
This domain is found in a variety of bacterial and fungal hypothetical proteins of unknown function. The structure of this domain has been solved by structural genomics. The structure implies a zinc-binding function, so it is a putative metal hydrolase (information derived from TOPSAN for Structure 3iuz).
Statistics
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PSSM-Id: 399801
View PSSM: pfam07063
Aligned: 135 rows
Threshold Bit Score: 167.388
Threshold Setting Gi: 255087921
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KIS68083          147 QMRALLASCMSSMYRCEVPLYGELVSIISSVNSDviraaantisddeisrlYVERHGAIRVG----------TAQELSLL 216 Ustilago m...
jgi:Ple7327_3029    5 QIARQLWERLWQDYSRRVEYARVYQSIIEEAGGA-----------------IANDHIAFRSLrltldrpmgkINLGIPYI 67  Pleurocaps...
jgi:Cyan7822_3610   5 ELTFQLWHRLWVDYRERVTYARIYEQMILDAGGK-----------------VANDHIAFRSLrltvncdhksVNLGIPYL 67  Gloeothece...
WP_015202301        5 QIALKLWNKLWKNYIYRVNYAQIYQQMIVTAGGT-----------------VANDHIAFRSLrlnvdtsqgtKNLGIDYL 67  Crinalium ...
WP_015153333        4 EIALHLWDRLWQQYRARVSYAQVYEQMILQAGGT-----------------VANDHIAFRSLrlnidtpegkQNLGIEYL 66  blue-green...
WP_015111039        4 ELASDLWEALWQEYQARVNYAQIYQNMIINAGGT-----------------LTNDHIAFRSLrlvvdtpqgeINLGINHL 66  Nostoc sp....
jgi:Cal7507_1106    4 QTALHLYSLLWQEYSARVSYARTYQQMITAAGGT-----------------VANDHIAFRSLrvlvdtqqgqINLGIEYI 66  Calothrix ...
Q8YUE6              4 RTALNLFSLLWQNYSARVTYARTYQQMITSAGGT-----------------VANDHIAFRSLrlsidrpqgkVNLGIGYL 66  Nostoc sp....
jgi:Npun_F1942      4 EIALNLWQLLWQEYSARVNHARTYQQMITTAGGT-----------------VANDHIAFRSLrllvdspqgeVNLGIDYL 66  Nostoc pun...
WP_038558451        7 EITNALLTQLWKMYLDRVSYAREYQRLVIGKGGS-----------------VVNDHIAFRTFnth----tgeQPEGIRAI 65  Draconibac...
KIS68083          217 ARIFKVFGMHPVGYYDLMrDAKLPIHAtaFRPVgrENLVKNPFRIFCSLLRLDCIADDETRMLAKQLL------ENRQIV 290 Ustilago m...
jgi:Ple7327_3029   68 ADIAEALGYEVAGEYEFP-DRYLSARH--YHHP--EQDRFDLPKLFISELVVDTLPDSIVRQIEATVS------SGNFFD 136 Pleurocaps...
jgi:Cyan7822_3610  68 ANLVEKLGYVVRGEYHFP-SSHLYARH--YQHP--EQDLYDLPKLFISELMVDELPEFIIQQIQKTVD------SGTFFD 136 Gloeothece...
WP_015202301       68 GKIAEALGYHAASEYTFP-DQKLYARH--YQHP--EQDALDLPKLFISELIVEQLPDAIAQLIYQTVN------SVKLAD 136 Crinalium ...
WP_015153333       67 ASVAEALGYTAAGEYIFP-AQKLYARH--YQHP--EQEQYDLPKLFISELIVEELPEAIASLIYQTVSdaslgwAMPSNA 141 blue-green...
WP_015111039       67 AQIALALGYEPAGEYKFA-ATHLYARH--YRHP--QQAEFDLPKLFISELIVDELPENIVRLIYQTVS------AIPEKS 135 Nostoc sp....
jgi:Cal7507_1106   67 GQLAEALGYVVAGEYTFP-ETHLYARH--YRHP--QQEEFDLPKLFISELIVDELPANTVQLIQQTIT------ANQYQL 135 Calothrix ...
Q8YUE6             67 SQIAEALGYEPAGEYIFP-QTHLYALH--YRHP--QQAEFDLPKLFISELIVDELPDKIAQLIVQTVS------TIPDNF 135 Nostoc sp....
jgi:Npun_F1942     67 AQFAEALGYVAAGEYNFA-QTHLYARY--YRHP--QQEEFNLPKLFISELIVDELPANIAQLISKTVS------AIPHQL 135 Nostoc pun...
WP_038558451       66 KHIISCLEYVPVEKYNFK-KKKLNAVH--FEHP-----DPMFPKLFVSQLEVEELPEWAQQIIKNTVK------ETPYLL 131 Draconibac...
KIS68083          291 SERCIELLVKAEmdlqtckdyqdDSKvsGLTRDEALEFVERVVDIF--AWHkdTPvSLEQYNLLAETHALVADIVsFRGP 368 Ustilago m...
jgi:Ple7327_3029  137 LEFLKPKIEATStd------------------aEIEQIATVLQTAFirPWE--PP-KRSLVESVNQVSQYGAWVL-LHGY 194 Pleurocaps...
jgi:Cyan7822_3610 137 LEQVSFDG-------------------------EKEQLLTQLQGVFtrPWA--VP-SKSVVEAVNEVSQYGAWVL-IHGY 187 Gloeothece...
WP_015202301      137 VETLVERIKLADte------------------lEAEQLTEELQLIYtrPWN--AP-FKSVVETVNPVSQYGAWVL-LHGY 194 Crinalium ...
WP_015153333      142 TNPT-----------------------------DIDLIVDRLQGVFtrPWS--PP-KQSVVEEVNRVTQYGAWVL-LHGY 188 blue-green...
WP_015111039      136 ISYLTPVVSNEN---------------------NLASIIQQLKQTFtrPWQ--IP-RRSVVEEVNKITQYGAWVL-LHGY 190 Nostoc sp....
jgi:Cal7507_1106  136 AFPLNHLFTKEE---------------------NLENTIQQLQKVFtrPWQ--PP-RRSIVEQVNQVTQYGAWVL-LHGY 190 Calothrix ...
Q8YUE6            136 TSPVKYFHQEKG---------------------NDEVIAQQLQKVFtrPWL--TP-RRSVVEEVNNITQYGAWVL-LHGY 190 Nostoc sp....
jgi:Npun_F1942    136 ASPVTLLKKDA----------------------EIETIAKQLQQVFtrPWL--PP-RRSVVEEVNQVTQYGAWVL-LHGY 189 Nostoc pun...
WP_038558451      132 SDESIGLLATLK-----------KKG--ELPRVAGEMLVKDLAQYFrrPWN--IP-KKDDVLKVNDVSQYAAWVL-LHGN 194 Draconibac...
KIS68083          369 HINHLTPRTL--------DIDQVQRTMLARGIDAKDVIEGPprreNEVYLRQTSFHALSESVEFL---GGntgtveGRHK 437 Ustilago m...
jgi:Ple7327_3029  195 AVNHFTGYINrqhtlqypDIESTARALAQRGVPMKDAIEGS----RGSGLRQTATQAVTELVDVWddaKGels--qiPWT 268 Pleurocaps...
jgi:Cyan7822_3610 188 GVNHFTGYINrqntakypDIESTAKGLADLGVPMKSTIEGS----RGSGLRQTATHAVTEMVTLKddtTGelt--qiPWT 261 Gloeothece...
WP_015202301      195 AVNHFTGYINrqntplypDIETTVKGLTDRSVPMKAEIEGD----LKSGLRQTATQAVQEGVTVIddtSKqev--siPWT 268 Crinalium ...
WP_015153333      189 AVNHFTGYVNrqhtlqypDIETTANGLATLGVPMKAQIEGS----LEVGLRQTATHAVKEIVTVIddvTGelm--qiPWT 262 blue-green...
WP_015111039      191 AVNHFTAYINrqntpaypDIETTASALANLGVPMKAEIEGN----VTCGLRQTATQAVTEMVNVLddsSHtei--qiPWT 264 Nostoc sp....
jgi:Cal7507_1106  191 AVNHFTGYVNrqntleypDIETTVLGLTNLGVPMKAEIEGN----IAYGLRQTATQAVTEMVTVLddiNSaei--qiPWT 264 Calothrix ...
Q8YUE6            191 AVNHFTGYVNrhqtpeyaDIDHTARGLANLGVPMKAEIEGD----VTWGLRQTATQAVKEMVTVIddiSGqev--eiPWT 264 Nostoc sp....
jgi:Npun_F1942    190 GVNHFTGYVNgqntpeypDIDTTASGLAHLGVPMKAEIEGN----VACGLRQTATQAVTEMVTVLddnSGvei--qiPWT 263 Nostoc pun...
WP_038558451      195 AVNHFTAFVNyqnvsewpDLESTCKGLAEAGIPMKETLEGE----KGSKLQQSATLAVKEEVEVK---GEdgi-ekMPWT 266 Draconibac...
KIS68083          438 ARFGEIEARGQALTRKGAQlydalmqqvacrkreveqksgakmekeecvqimqhvfqdgfpdskdellrqglgyftfsin 517 Ustilago m...
jgi:Ple7327_3029  269 YAYYEIAERNFIEISPGKT------------------------------------------------------------- 287 Pleurocaps...
jgi:Cyan7822_3610 262 YAYYEIAQRNIIESEAGKT------------------------------------------------------------- 280 Gloeothece...
WP_015202301      269 YAYYEIAERALVEVTPGEK------------------------------------------------------------- 287 Crinalium ...
WP_015153333      263 YAYYEIAERYPVEAA-GKK------------------------------------------------------------- 280 blue-green...
WP_015111039      265 YAYYELAQRYLIETQPGKP------------------------------------------------------------- 283 Nostoc sp....
jgi:Cal7507_1106  265 YAYYEIAQRYPVEIEPGKH------------------------------------------------------------- 283 Calothrix ...
Q8YUE6            265 YAYYEVAQRYPLQVEPGKE------------------------------------------------------------- 283 Nostoc sp....
jgi:Npun_F1942    264 YAYYEIAQRYPVEVEPGKQ------------------------------------------------------------- 282 Nostoc pun...
WP_038558451      267 YAYYELAERGLVIEN-GEE------------------------------------------------------------- 284 Draconibac...
KIS68083          518 dgqlaknmwerqsqasascdlladmvksgalhaepITYEDFLPASAAGIFQSNL 571 Ustilago maydis 521
jgi:Ple7327_3029  288 -----------------------------------ALFEGFLNTQAKNLFEMTR 306 Pleurocapsa sp. PCC 7327
jgi:Cyan7822_3610 281 -----------------------------------ILFEGFLDAQAKNLFEMTR 299 Gloeothece verrucosa PCC 7822
WP_015202301      288 -----------------------------------VLFQGFKGANAQQLFEMTR 306 Crinalium epipsammum
WP_015153333      281 -----------------------------------VLFDAFLGQNAQHLFEMTR 299 blue-green algae
WP_015111039      284 -----------------------------------ELFEAFLSKNAQQLFEMTR 302 Nostoc sp. PCC 7107
jgi:Cal7507_1106  284 -----------------------------------LLFDAFLGKNAQQLFEMTS 302 Calothrix sp. PCC 7507
Q8YUE6            284 -----------------------------------ALFDGFLGNNAQQLFEMTR 302 Nostoc sp. PCC 7120
jgi:Npun_F1942    283 -----------------------------------ILFDAFLGSNAQQLFEMTR 301 Nostoc punctiforme PCC 73102
WP_038558451      285 -----------------------------------KLFSGFLGEQARHLFDMTR 303 Draconibacterium orientale
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