Conserved Protein Domain Family
Orthopox_C10L
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pfam07020: Orthopox_C10L 
Orthopoxvirus C10L protein
This family consists of several Orthopoxvirus C10L proteins. C10L viral protein can play an important role in vaccinia virus evasion of the host immune system. It may consist in the blockade of IL-1 receptors by the C10L protein, a homolog of the IL-1 Ra.
Links
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Statistics
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PSSM-Id: 115660
View PSSM: pfam07020
Aligned: 4 rows
Threshold Bit Score: 40.8289
Threshold Setting Gi: 75546520
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6TVI3     1 MSGTPRYGMYDQGGNYKGTANDPGGACKRPhslSSGGGssdgsgwgsMWGGPPAKKHCGGGGGGIFagmyggsGGSGGIC 80  Bovine papular stom...
Q6TVW4     1 MPGEGQYHIYSHSGTSKGFASTPGGAVKRP---SSGSG---------IWGPLEKRMCVGGGSGGFW-------GGSKSLS 61  Orf virus
P17356     1 MSSKGG----SSGGMWSVFIHGHDGSNKGSktyTSGGGg--------MWGG----------------------GSSSGVK 46  Vaccinia virus WR
NP_619815  1 MSSKGG----SSGGMWSVFIHGHDGCSKGSktyTSGGGg--------MWGG-----------------------SSSGVK 45  Cowpox virus

Q6TVI3    81 GGVKGGVSGGINGGISKI 98  Bovine papular stomatitis virus
Q6TVW4    62 GGVNGGVNGGVNGGCGKI 79  Orf virus
P17356    47 S----GVNGGVKSGTGKI 60  Vaccinia virus WR
NP_619815 46 SGVNGGVNGGVNSGVNKI 63  Cowpox virus
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