Conserved Protein Domain Family
Involucrin2
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pfam06994: Involucrin2 
Involucrin
This family represents a conserved region approximately 60 residues long, multiple copies of which are found within eukaryotic involucrin, and which is rich in glutamine and glutamic acid residues. Involucrin forms part of the insoluble cornified cell envelope (a specialized protective barrier) of stratified squamous epithelia. Members of this family seem to be restricted to mammals.
Links
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Statistics
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PSSM-Id: 429235
Aligned: 17 rows
Threshold Bit Score: 29.3651
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_008262643 118 EPQVQEVHVGQQQpqvqevhvgqqPEPQVQEVHvgQQP--EPQVQEVHVGQ 166
XP_006501110 173 MLVPQELHLRQHQ-----------EKLQDPELHlgQQQk-TPEEQKLIPGE 211
EHB13102      59 EPQEEELYLRQQQh---------pQKPPEPELHlgKQQ--EPQEPE-QPPE 97 
P48997       310 KLHKPELYLRKQQy---------qE-SPDPELSlgKQQhqECQEPELQLEE 350 house mouse
P48997       223 EPQEQELHLGQKQk---------qK-LHEPELQlgKQQhqKPSEPELPLGK 263 house mouse
NP_071531    390 KSPEPELHLGKQQ------------ELHEPDMTedQKEkqSLHEPELHLGK 428 Norway rat
NP_071531    317 ESCEPELHLGKQQh---------qE-TQESELQlgKQQ--KPHEPDMVLDP 355 Norway rat
XP_003803978  82 GPQEPELHLGKQQdvhl----mkrQDPQEPELHlgKQP--EPEGPEPHLGK 126
XP_027241385 241 HQESRELHLRQRQk---------qKKHCEPEPHlgKQQsrESPEPEVHLGK 282 Chinese hamster
XP_006232869 155 VLAPQELHMGQHQk----------EKLQEPELPlgQQQk-TPEEQELILGE 194
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