Conserved Protein Domain Family
HemN_C

?
pfam06969: HemN_C 
HemN C-terminal domain
Members of this family are all oxygen-independent coproporphyrinogen-III oxidases (HemN). This enzyme catalyzes the oxygen-independent conversion of coproporphyrinogen-III to protoporphyrinogen-IX, one of the last steps in haem biosynthesis. The function of this domain is unclear, but comparison to other proteins containing a radical SAM domain (pfam04055) suggest it may be a substrate binding domain.
Statistics
?
PSSM-Id: 399746
Aligned: 46 rows
Threshold Bit Score: 43.7748
Threshold Setting Gi: 81603226
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EDO44873                           303 QSNAVILEEIIMLGLRT--SEGIPNERFNHYITATssgslreifegCSDVRDFMAEGLLQLDERGLRATPSGLA 374 starlet sea anemone...
Q6MC79                             311 LDPIAHLKELFVIQIRL--CQGISIADFEQRHGKlsq-------etLETIEQFILDGFLTQSNQILSLTKKGVL 375 Candidatus Protochlamydia amoebophila UWE25...
WP_011913101                       347 ANHIDPLHRLLLERLLC--TFALDFDALSLQSGVDvrqry--aqhwPA-LRQLHADGVIVLDDSGLRVPAQARL 415 Pseudomonas stutzeri...
WP_011942334                       358 LDDEDRLRGAIIERLMC--DLEVDLAA----FGADparf---arecES-LAPLEADGFLHREGSRISITEAGRP 421 Acidiphilium cryptum...
Q8KLE7                             379 LATEDRVRAAIIEQLMC--YLEADISAICTAQGFDqthl---vssaKQ-LEILAEDGIVEFDNGLVSVRHERRS 446 Rhizobium etli CFN 42...
Q4FPT5                             421 TSIKDRLREYVIMNLLC--HDYMDFRDINQKFGIDaityf--ineiQQ-LGQMQEDRLIDMDAAGIRVLPRGRL 489 Psychrobacter arcticus...
WP_011985443                       363 VTADDVMRRFVINRVMC--LLKLDLREVAEKFGPAarkti--eadlAKGVEELQGDGLVTFDGELLRVTPLGQL 432 Anaeromyxobacter sp. Fw109-5...
Q6LLR0                             363 LDADDLLRREVIKALIC--NFQLDMKDIEQRFNLTfneyf--aedlGL-LKTFINDELVTIDGQFIHVELKGRL 431 Photobacterium profundum...
O25376                             365 LSQEDVLRKEVIMQMMS--NLKLDYSKIEEKFSVDfkahf--kkelEK-LKPYEEAGLLSFNSKGFEMTKTGGM 433 Helicobacter pylori 26695...
WGS:AAXU:1101174000280_ALPR1_07400 363 LSEKDIIVREIILDIICqhQAEIPLDIWESLNEKQ-----------IFNLKEMQWEGLLSIDKSKLKVNSQGIA 425 Algoriphagus machipongonensis...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap