Conserved Protein Domain Family
zf-LSD1

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pfam06943: zf-LSD1 
LSD1 zinc finger
This family consists of several plant specific LSD1 zinc finger domains. Arabidopsis lsd1 mutants are hyper-responsive to cell death initiators and fail to limit the extent of cell death. Superoxide is a necessary and sufficient signal for cell death propagation. LSD1 monitors a superoxide-dependent signal and negatively regulates a plant cell death pathway. LSD1 protein contains three zinc finger domains, defined by CxxCxRxxLMYxxGASxVxCxxC. It has been suggested that LSD1 defines a zinc finger protein subclass and that LSD1 regulates transcription, via either repression of a pro-death pathway or activation of an anti-death pathway, in response to signals emanating from cells undergoing pathogen-induced hypersensitive cell death.
Statistics
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PSSM-Id: 399727
View PSSM: pfam06943
Aligned: 78 rows
Threshold Bit Score: 31.6529
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFH67254     114 CGNCKMLLMYQYGARSVKCAVCNFI 138 Arabidopsis lyrata subsp. lyrata
EFH43884       7 CSSCRTPLHLPPGATRIRCAICHAf 31  Arabidopsis lyrata subsp. lyrata
XP_006365337   7 CTNCHTTLQLPSGAQSIRCAICCat 31  potato
CBI16704      53 CAHCRTPLQLPAGARSIRCAICQGv 77  wine grape
XP_002318795   5 CSNCSSPLQLPPGANSICCSICHAt 29  black cottonwood
XP_002526488   7 CSHCWTPLQLPPGARSIRCSICRAV 31  castor bean
XP_002280421   7 CSNCRIPLQLPPGARAIRCSVCHAV 31  wine grape
XP_006375191   9 CSKCQTPLQLPPGAESIRCVICQAV 33  black cottonwood
XP_010318207   7 CSKCHTPLQLPPGAKSIRCAICRAI 31  tomato
ONI22288       7 CSNCRTPLQLPPGAESIRCALCQAV 31  peach
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