Conserved Protein Domain Family
DUF1275

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pfam06912: DUF1275 
Protein of unknown function (DUF1275)
This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.
Statistics
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PSSM-Id: 399716
Aligned: 566 rows
Threshold Bit Score: 51.0685
Threshold Setting Gi: 328811530
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009154277         27 IILCFFISGLIDSVAF-NSWNCFVDMQTGNTVFAALGlggqpkasHSQQYykSL-TSI-GAFCLGTLFFNtlhrFPtgfa 103 Exophial...
Q8DWC3               25 AYFLTLLGGAIDAVSYmGFDHTLPAAQTGNLLLLMVDitr--lnvQGIAI--KM-TTL-LSFIAGLVVSR----CAyhyy 94  Streptoc...
WP_011102073         16 GLGLTCIGGFIDAYTFiQRGGVLAAGQTGNLIFLSVDvaq--wnlPGVLT--KL-ATV-LFFTLGVIVVG----ILkqwl 85  Lactobac...
Q03QJ5               16 AMGLTFIGGFIDAYTFgQRGGVLAAGQTGNLIFLSVDiaq--hnlPGVLT--KL-LTV-VFFILGVVTVG----LLnyrl 85  Lactobac...
Q8DPT8               21 ALFLTFCAGYVDAYTFiVRGNTLVAGQTGNVVFLSVElik--nnvSDVRD--KV-LTL-LAFMMGVFLLT----IYkekl 90  Streptoc...
Q5FK02               23 ACALTFCGGFIDAYTYiQRGHTLSAGQTGNVIFFSSAlad--hniPGMIN--RA-STF-IAFSLGLLLVG----LFhkyv 92  Lactobac...
jgi:Lreu_1248        17 ALLLTFSGGFIDAFTYiKCGRTMAAAQTGNIIFLSAAlan--hnfLGVVD--RL-GSL-IAFILGLAMVS----ILhahl 86  Lactobac...
cebbi:LBUCD034_2351  11 TLAQTFIMGSIDAYTFqNFDGSFVSAQTGNLVIFAYElat--kgwSTA----YIrVPVlLGFLLGAFISQ----AFkhiq 80  Lactobac...
WP_013977123         20 feLLIFSAGMMGAYTYmMRGQVFCNAQTLNVVMMAIElgq--rhyEQSAY--YL-IPI-GAYLAGAIVAE----FLpert 89  Clostrid...
CDD28925             16 FALLTLSAGMMGAYTFnLRGGVFCNAQTANVVLMAIAfgs--gewGQGCY--YL-IPI-TAYLAGAFLSE----ILpspv 85  Firmicut...
XP_009154277        104 e--qassRRRSTFIASfsiqTALIVVATVLvSqdLvSNqpflpgafssgsndkdsrppamtnfldlcPVSLLSFQAAGQV 181 Exophial...
Q8DWC3               95 ---rsiyWRIYILVGLsaacLFTFLAFDHL-P--Sgl-----------------------------aI-APLSFTLAMTT 138 Streptoc...
WP_011102073         86 g-arshyWRLPVLVAE----LVVCLMVGML-P--AtVSna--------------------------mVVPPLAFVMAMQT 131 Lactobac...
Q03QJ5               86 r-ptshyWRLPTLLAE----FVVCLVVGGL-P--EtVPnl--------------------------iVTPPLAFVMAMQT 131 Lactobac...
Q8DPT8               91 ---rivkKPILSLIPL----AILSIIIAFV-P--QtVDni--------------------------yLVPPLAFCMGLVT 134 Streptoc...
Q5FK02               93 ---kshyWRVFCLFPI----LVICIVVGFL-P--KsVPny--------------------------yIVPAIAFGLAVQN 136 Lactobac...
jgi:Lreu_1248        87 ---rtdyWRVVCLLPI----LLVGAIIGFL-P--DsFPdy--------------------------lMVPAVSFGLAMQS 130 Lactobac...
cebbi:LBUCD034_2351  81 ---lasdRRFNVLLLFsiilLGILAVAA---AfhLsMLn----------------------------mLFSLGLFSGYEL 126 Lactobac...
WP_013977123         90 rnkyaihSGVYIIALE----MAVLALIGFV-P--LsAPdq--------------------------iAQVAVNFIASMQF 136 Clostrid...
CDD28925             86 rrfgflrWDTYLVAFE----FLALFSIGFI-P--LgWPhq--------------------------lVQVLVNFIASMQY 132 Firmicut...
XP_009154277        182 TL-SRlLGMvELPTIVLSALYHDFTAD----------LlairtswKRSpSLWEflvvqqrrqgrRLACIIALFIGGIIGG 250 Exophial...
Q8DWC3              139 GAfNK-VENeLYNNSFTTGNIKKAIIAwceflfkgqaE-------QKE-RAVI-----------FTCLVLSFVIGAFTAA 198 Streptoc...
WP_011102073        132 TAfSA-IAGhGYNNVFSTGNLKKATIAltnywltgvrT-------ELD-TGLV-----------YWELVLSFATGAIVSA 191 Lactobac...
Q03QJ5              132 TAfGH-IEGhGYNNVFSTGNLKKATSAltdyfiyrqpG-------TLT-TGII-----------YGGLVVSFAGGAIISA 191 Lactobac...
Q8DPT8              135 TAfGE-VSGiAYNNAFMTGNIKRTMLAfgdyfrtkhtP-------FLR-EGFI-----------FVSLLSSFVLGVVFSA 194 Streptoc...
Q5FK02              137 ASfSK-IEGmGYNNVFTTGNLKKSVVAwsafffgedkS-------KYT-AAVN-----------YMMLVISFGLGAIVSA 196 Lactobac...
jgi:Lreu_1248       131 AAfSK-IEGlGYNSVFTSGSVKKAAVAwseyyfhhdrS-------QRS-AAFS-----------YLMIVICFTLGAIISA 190 Lactobac...
cebbi:LBUCD034_2351 127 TVfNK-IGTtSVNNGIMTGNLKNFANNsyeaifshdrE-------ALL-KAGR-----------FLSGIIMFILGIIFSA 186 Lactobac...
WP_013977123        137 TNfRK-SEGyPMATTFATNHLRQIGIAivdyrrtrdlQ-------YRK-RLFK-----------HLRMLLMFFAGAAVLS 196 Clostrid...
CDD28925            133 NTfRQ-AEGiPMATTFCTNQLRQVGVGfakalrkhdrE-------GLS-RALF-----------FLGMLGCFFAGGVLST 192 Firmicut...
XP_009154277        251 EMYKSragmAGALWLAAGAKLAIVVA 276 Exophiala dermatitidis NIH/UT8656
Q8DWC3              199 LFYFLf--gMAALLVILCEIIIFTVC 222 Streptococcus mutans
WP_011102073        192 ILQRWw--tLRTIWVAAGLSILVGGY 215 Lactobacillus plantarum
Q03QJ5              192 LLQGWl--lGRTIWCAAGLLLIVGGY 215 Lactobacillus brevis ATCC 367
Q8DPT8              195 YLTIFy--hEKTILGVPIMMSVFYLS 218 Streptococcus pneumoniae R6
Q5FK02              197 LLQKIw--vLKTIWIAVIFLAIINCI 220 Lactobacillus acidophilus
jgi:Lreu_1248       191 QLLPFf--rMKTIWIAT-FLILVtds 213 Lactobacillus reuteri DSM 20016
cebbi:LBUCD034_2351 187 YLLHAa--gPKVFGAALMINLVLLII 210 Lactobacillus buchneri CD034
WP_013977123        197 LATGPl--qERAIWLALIPLTVCFII 220 Clostridium sp. SY8519
CDD28925            193 LACHLv--fAKAIWLNLLPLGIVLVr 216 Firmicutes bacterium CAG:94
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