Conserved Protein Domain Family
DUF1269

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pfam06897: DUF1269 
Protein of unknown function (DUF1269)
This family consists of several bacterial and archaeal proteins of around 200 residues in length. The function of this family is unknown. The family carries a repeated glycine-zipper sequence- motif, GxxxGxxxG, where the x following the G is frequently found to be an alanine. As glycine-zippers occur in membrane proteins, this family is likely to be found spanning a membrane.
Statistics
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PSSM-Id: 399703
Aligned: 88 rows
Threshold Bit Score: 32.4806
Threshold Setting Gi: 183174580
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFG83327       65 FSGGFWGALVGLLFLNP--LAGfvagSV-VGAGAGALAGS-MT--DYGIDDKFIKSLGATIPANTSALFVLVRK---SQP 135  Komagataeibac...
WP_014690953   61 TWGMFWGLLFGMLFFIP--VLG----MA-VGAGLGALTGK-LA--KGAINKEFQERIRDELQPGTSALFLVVES---VTP 127  unclassified ...
CCA60390       61 ASGALWGAIFGLLFLLP--GVG----LL-TGAALGGLVGK-LS--KSGVDDRFRQQVADLLTPGSAAVVIMASK---ITD 127  Streptomyces ...
jgi:Namu_4746  61 ASGALWGMLIGLLFFVP--FFG----LA-LGGLMGALFGK-LG--KSGINDEFRSQVNSLLEPGNAAVVIMASK---ITD 127  Nakamurella m...
ESQ09893       61 LAGMLLGSLIG-VFGGP---IG----VA-MGAATGSLVGLvGDtvRAGVNDDFLAEVMETLTPGKFALVAEIGE---HWT 128  uncultured De...
Q5FS67         64 LNGTLLGSLVGLLL-GP---LG----VL-LGASMGALVGSsLSveDAAIRSSLLAQIASVIPVGTTAVIATVQEyvpQVV 134  Gluconobacter...
ESQ15459       63 gWGLLTGGLVGMLF-GP---GGaaagAA-MGGGFGSMMGL-VD--ETAFDDPVLSDFAKSLDRNSSALILVGEQ---PTI 131  uncultured Th...
VBC:MMAR_1232  66 AWGAGAGLAVGL--FSPalLAS----TA-VGAAAGALAGT-FI--QHRVKSGLADKIGQALSAGSAVVIAVTPA---QGR 132  Mycobacterium...
jgi:Cwoe_0771  63 wTGLGVGAVLGILF--PpsLIG----TAlVGGAFGGLVGHfWR----GLPRNALKELGETLDEGEAALFVVGES---TVE 129  Conexibacter ...
BAI91299       68 IMGGITAGLIAL--FNPigALGviamTA-GGAGVGALVTH-FI--DLGFPQEDLKDLSESLTPGSSALIALVEQ---TWV 138  Arthrospira p...
EFG83327      136 DKVLADLSQFK--GhaRVLQTSLSPADENKLRAALG 169  Komagataeibacter hansenii ATCC 23769
WP_014690953  128 DKAVEALSHYG--G--TVLKSSLPKETEEELQEALH 159  unclassified Actinoplanes
CCA60390      128 DKFTVAMQPHG--G--TVLKTSLSDEDEKDLAEQLA 159  Streptomyces venezuelae ATCC 10712
jgi:Namu_4746 128 DKFADRMSKYG--G--KLLKTSLSEEDEKELAHELG 159  Nakamurella multipartita DSM 44233
ESQ09893      129 TPLDTRMEALG--G--TVFRTWRIDVEDEQLERniq 160  uncultured Desulfofustis sp. PB-SRB1
Q5FS67        135 DDLAASL------GasLVLRRPIEAVEREVLAQQka 164  Gluconobacter oxydans
ESQ15459      132 DDFASAVEPLG--G--EIVSTDIDEKDIKALRKVLK 163  uncultured Thiohalocapsa sp. PB-PSB1
VBC:MMAR_1232 133 LPVEQTLSGSPmkS-----VAELSRSTMRSLGAALq 163  Mycobacterium marinum M
jgi:Cwoe_0771 130 EAVRAAVARAD-----KLVAKEL-KAESKELKKALE 159  Conexibacter woesei DSM 14684
BAI91299      139 EKVCEELAKFE--G--KLYRRAIKEELAAQLTETak 170  Arthrospira platensis NIES-39
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