Conserved Protein Domain Family
DUF1256

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pfam06866: DUF1256 
Protein of unknown function (DUF1256)
This family consists of several uncharacterized bacterial proteins which seem to be specific to the orders Clostridia and Bacillales. Family members are typically around 180 residues in length. The function of this family is unknown. These proteins are related to peptidase family M63 and so may be peptidases.
Statistics
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PSSM-Id: 115518
View PSSM: pfam06866
Aligned: 13 rows
Threshold Bit Score: 184.398
Threshold Setting Gi: 81530172
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8R6L8   3 FINIEDKNAFENFYRTFQFYFKNLykepYREIILLCIGTDRSTGDSLGPLTGHKLKPLLRNKAHVFGTLEDPLHAKNIID 82  Caldanaerobacter subt...
P37521  17 YVSHTDAAAAKQIQTILSSSLRKAa---GKPIVVVCIGTDRSTGDSLGPLVGMKLKQMQLTRFHVYGTLSDPVHAVNMKD 93  Bacillus subtilis sub...
Q97CW9   6 VFNVDDSNILYSFSNYLSSEIKSIa--vNRDIVFLCIGTDRSTGDSLGPMVGYKLTKFHKNNLIVFGTLQEPVHAKNLCN 83  Clostridium acetobuty...
Q899R5   6 IINSNSKSAIITLRDTLCGYITPVla-sGKHIILLCIGSDRSTGDSLGPLVGHNLKFLSRNNFHVFGNLEMPVHAKNLHQ 84  Clostridium tetani
Q8XH36   6 YINSLDPKASFKIRDYLCRELSPVik-eNRPIVFICIGSDRSTGDALGPLIGEKIKFLSKNNIFIYGTLEETVHAGNLKE 84  Clostridium perfringens
Q97HP9  17 FSYNVDKENIEHWISAILFQVLKD----KEDIVILSLGVDTLVGDSLGPLVGSILKRNGIP--NVYGTLDRTVNASNIIK 90  Clostridium acetobuty...
Q97HQ0   4 EKYYYEKNIQEEFFKFLYSMTGK-----KEEIVVICIGDPVFEGNILAPLVGTLLHERNIP--NVYGTLKEPVYEINIKE 76  Clostridium acetobuty...
Q8RCE8   5 RLRYNEEKASFQIANFLSRHL-------LPETVFLCIGTDRFITDSLGPIVGNLISGSLPPIYYVYGTLKNPVHAINLEE 77  Caldanaerobacter subt...
Q898W9   5 MVHYNDPLAYKIMGETLSNFL-------NNNTIIVCVGTDKCIGDSLGPITGTILKEKNFP-LPVFGTVENPIHALNIKV 76  Clostridium tetani
Q8XIE2   5 KIYYKNYLAYYEISNFLKNHI-------DEKTIIVCIGTDKCIGDCLGPLVGTLLKEKFFP-LKVFGTLDSPIHALNLDK 76  Clostridium perfringens
Q97F84   5 KAFYNLPMAYYRLSNFLKHYI-------DDNTIIICIGTDRCIGDCLGPMVGTMLKEKFFP-LNVYGTISEPIHALNIDK 76  Clostridium acetobuty...
Q8EKU9  15 RLHYKENN----LPSLMCQHIMNWfpyqPREYVAVFIGTDRSTGDALGPLAGMYFQSYKPRHIRVYGTIHEPVHAVNLEE 90  Oceanobacillus iheyensis
Q9K5N4  15 RVHMDDPQASDQLVEQLLTHVSSYr---HRELVIVCIGTDRSTGDALGPIVGTALTKECLNCFHVYGTLADPVHAVNLEE 91  Bacillus halodurans
Q8R6L8  83 VLKEIRNTFYMPFTIAIDASLGSL--KHVGHISIGKGPIKPGAGVSKELPPVGDMFVTGIVNISGFMEYM---VLQNTRL 157 Caldanaerobacter subt...
P37521  94 KINDIHKLHKNPFVIAVDACLGRV--KSVGSFQIGDGPLKPGAGVQKDLPEVGDLHINGIVNVSGFMEYF---VLQNTRL 168 Bacillus subtilis sub...
Q97CW9  84 TMDIIKTKYENPFIIAIDACLGST--KTVGNIVIQNTPLSPGSAMNKSLPTVGDLSITGIVNVSGPFDFM---VLQSTRL 158 Clostridium acetobuty...
Q899R5  85 ILKYINKKFDDPYIIAVDACLGHI--QNIGKVFVEDKPLKPGSAVNKDLPPVGNLSITGIVNISGTLEFM---VLQNTRL 159 Clostridium tetani
Q8XH36  85 TVKIIKSKHKKPFIIAIDACLGAV--DNVGHVLIEKRPLKPGIALNKDLPEVGDLSILGIVNISGSLEFM---VLQNTRL 159 Clostridium perfringens
Q97HP9  91 ILDEIHERFKNPYILVVDAAVTAE--NNINDIVLRNGGFTPGFGVYRQLPTVGDFSLVGVVNKEDEREHNlieLLKKCRF 168 Clostridium acetobuty...
Q97HQ0  77 IYNKILKKYDNPYIILVASSFPVDfhDEREVIVLKNDPYEIQTASGS--LKLGNASFIVVFDLEDS--YCkvnFIEKLGI 152 Clostridium acetobuty...
Q8RCE8  78 NLRYIKKKHPYSKIIAVDASLGEE--ENIGKISIKKSPIHPGKGVGKILPPVGDLSIVGIVDSFHAKDLN------SIRL 149 Caldanaerobacter subt...
Q898W9  77 KMSEIASLYPNHNIIGIDACLGES--NNIGFIQSRNYPIYPGKGVGKKLPHVGNHSIVGIVDSTEINIFN----NNSIRL 150 Clostridium tetani
Q8XIE2  77 KITEILKTYPGYKILAIDACLGDS--NSIGEIHARNEPIHPGKGVGKSLRSVGDMSIIAIVDSSENIDLF---TSRPIRL 151 Clostridium perfringens
Q97F84  77 KLYKIKKDHTNSTIIGIDACLGDT--ENIGEIQVRDYAIHPGKGVGKSLPDVGEVSIVGIVDSCESSELF---TNRNIRL 151 Clostridium acetobuty...
Q8EKU9  91 SLERIDKLHNNPFIIAIDACLGRS--TSIGHIITEKKSLQPGTALNKTLPAVGDVSITGVVNVSGFMEHS---ILQNTRL 165 Oceanobacillus iheyensis
Q9K5N4  92 KLKLIEKKHRRPFIIAIDACLGKL--SSVGKVSLAAGPVQPGAAVNKKLPAVGDVHLTGIVNIGGMMEYF---VLQNTRL 166 Bacillus halodurans
Q8R6L8 158 RTVMKMADIIAAG 170 Caldanaerobacter subterraneus subsp. tengcongensis
P37521 169 NLVMNMANVLAEG 181 Bacillus subtilis subsp. subtilis str. 168
Q97CW9 159 YSVLKLADIISRG 171 Clostridium acetobutylicum
Q899R5 160 FTVMQLAELISNG 172 Clostridium tetani
Q8XH36 160 YTVMLLANAISNG 172 Clostridium perfringens
Q97HP9 169 DEVLKLARIISKI 181 Clostridium acetobutylicum
Q97HQ0 153 RKIYKYSEAIFKT 165 Clostridium acetobutylicum
Q8RCE8 150 GFIYEIAETIANG 162 Caldanaerobacter subterraneus subsp. tengcongensis
Q898W9 151 NFILNMAKSISHS 163 Clostridium tetani
Q8XIE2 152 SFILDMSKVIVDS 164 Clostridium perfringens
Q97F84 152 NLIFEMSKVIVQT 164 Clostridium acetobutylicum
Q8EKU9 166 SVVMDMAKQVSSI 178 Oceanobacillus iheyensis
Q9K5N4 167 HTVMQLADTISSS 179 Bacillus halodurans
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