Conserved Protein Domain Family
ACP
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pfam06857: ACP 
Malonate decarboxylase delta subunit (MdcD)
This family consists of several bacterial malonate decarboxylase delta subunit (MdcD) proteins. Malonate decarboxylase of Klebsiella pneumoniae consists of four different subunits and catalyzes the conversion of malonate plus H+ to acetate and CO2. The catalysis proceeds via acetyl and malonyl thioester residues with the phosphribosyl-dephospho-CoA prosthetic group of the acyl carrier protein (ACP) subunit. MdcC is the (apo) ACP subunit. The family also contains the CitD family of citrate lyase acyl carrier proteins.
Links
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Statistics
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PSSM-Id: 399681
Aligned: 131 rows
Threshold Bit Score: 45.9379
Threshold Setting Gi: 524058684
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q24T13          4 STTAKAGALESNDVLVTVMPNd-QGGVQIQLETkrVIfKQFGKQIEEVVRDKVAEMGVDNVIVKVQDKGALDYTIRARVQ 82  Desulfitobacte...
WP_009550652   23 faPVLVGVVGSGNLEVLLEPAt-PPACRVHVET--SA-HGFGGIWQAVLEDFHARHALAGVQVSIHDMGATPAVVSLRLD 98  Burkholderiale...
WP_012345115   23 faPVLVGVVGSGNLEVMVEPAa-GSHCSVEVET--SA-RGFRPIWQAVLSDFHDRHALAGVRVSINDMGATPAVVSLRLE 98  Leptothrix cho...
Q8P4U6         18 lDHALVGVVASGNLEVLVERVplGGAMEIEIVT--AA-RGFGEIWQAVLDDFAARHSLQDVRISINDVGATPAVVSLRLE 94  Xanthomonas ca...
nioo:CFU_1709  18 pqaQLSGVVSSGNLEVLVEAAalNGACAIEIKT--AA-RGFGAIWEAVLGDFQQRWQLADARIAINDMGATPAVVSLRLD 94  Collimonas fun...
WP_011870975   17 phaELVGVVSSGNLEVLIETAvlNGGCEVEVKT--AA-VGFAAIWQAVIADFHLRWSLADVRISINDVGATPAVVSLRLD 93  Herminiimonas ...
jgi:Veis_2895  19 SAPVLVGVVGSGNLEALFEPRplAGIIRFVVDT--PI-AGFDATWRAVLADFAARQRTGDLLVTINDAGATPAVVALRLA 95  Verminephrobac...
jgi:Mpe_A0793  18 qAPALAGVVSSGNMEALLEPKalDGRLRFVIDT--SI-EGYTDTWQAVAANFAARHRVGNLLVTVNDAGATPSVVALRLA 94  Methylibium pe...
Q4FSL2         17 MKEVICGVVGSGNLEILVSSItdNEHSEFIINT--SV-TGFDHIWEAVIQEFVNRYAVGGLQFEINDMGATPAVVSLRLS 93  Psychrobacter ...
Q5ZST9         22 spMIKVGVAGSGNLEVIIKPNsnFDKTDIIVNT--VI-SGFRNTWDAVIERFVEDYPYGGLSITLNDAGATPPVVSLRLR 98  Legionella pne...

Q24T13         83 TALERA 88  Desulfitobacterium hafniense Y51
WP_009550652   99 QAVAEL 104 Burkholderiales bacterium JOSHI_001
WP_012345115   99 QAVAQM 104 Leptothrix cholodnii
Q8P4U6         95 QAIDVl 100 Xanthomonas campestris pv. campestris str. ATCC 33913
nioo:CFU_1709  95 QALQAM 100 Collimonas fungivorans Ter331
WP_011870975   94 QAVESM 99  Herminiimonas arsenicoxydans
jgi:Veis_2895  96 QAAEEL 101 Verminephrobacter eiseniae EF01-2
jgi:Mpe_A0793  95 QAMEEL 100 Methylibium petroleiphilum PM1
Q4FSL2         94 QAINil 99  Psychrobacter arcticus
Q5ZST9         99 QAMETy 104 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
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