3I16,3JZL


Conserved Protein Domain Family
Met_gamma_lyase

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pfam06838: Met_gamma_lyase 
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Methionine gamma-lyase
This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.
Statistics
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PSSM-Id: 429146
Aligned: 15 rows
Threshold Bit Score: 704.467
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3I16_A  19 VLKLYETAXNDIQNQFKILDDIREFNQLKVLNAFQEERISEAHFTNSSGYGYGDIGRDSLDAVYARVFNTESALVRPHFV 98 
P94479  11 LKKTAMEVEADIAGIHKQIEEISERNEWRVLQSYRKHKVSDTHFTPSTGYGYDDIGRDTLESIYADVFGGEAGLVRPQII 90  Bacillus subtilis sub...
Q8Y7I1   4 IQAMRKKVEVQIADLQNETDEIAEFNQAKVLDAFQENKVSDFHFHPSTGYGYDDEGRDTLEHVYATVFKTEAALVRPQII 83  Listeria monocytogenes
Q9KAC8  11 IEKAKRNAEQKIVSNVEHVEHIALVNQKRVLDAFKRKQVSEHHFTPSTGYGYDDLGRETLEAVYADVFGAETALVRPQII 90  Bacillus halodurans
Q5HPN4   4 fSNLVEKVENTLIPYFRKIEKRALFNQEKVLNAFHHVKASESDLQGSTGYGYDDFGRDHLEQIYAHTFKADDALVRPQII 83  Staphylococcus epider...
Q8EQP5   1 MESLIEQAEQDCSLQQKDIQKNVEINQKRVLNAFRHHRISDSHLQGTTGYGYDDIGRDSLEAVYAEVFGGEDALVRPQLV 80  Oceanobacillus iheyensis
Q8DHD9  26 RTSLLTAAQGALVTRFAEIDGRVKKNLDRVLAAFRQHRLGVHHFSSMTGYGHGDLGREVLDRVFAQVMGAEAALVRVQFV 105 Synechococcus elongatus
Q55407   3 YSSFLKQAEENLVPIFSEIDAKVKENLYKVIEAFRHHRVGVQHFAGVSGYGHDDLGRDTLDGVFAQVMGAESAAVRVQFV 82  Synechocystis sp. PCC...
Q54763   3 TPQLVSEAEAELLQIFVGLDVQVKENLGRVLEAFRAERVGVHHFAGVSGYGHDDLGRETLDRLYARVFGAEAAAVRIQFV 82  Synechococcus elongat...
Q8RA65  17 VIELIESAEKSCLDIFKKIDEIVEYNQYKVIYHFQKNKLSDIHFNGTTGYGYGDIGRDVIEKIYAGIFGAEDALVRPQIV 96  Caldanaerobacter subt...
3I16_A  99 NGTHALGAALFGNLRPGNTXLSVCGEPYDTLHDVIGITeNS-NXGSLKEFGINYKQVDLKEdGKPNLEEIEKVLKEdeSI 177
P94479  91 SGTHAISIALFGVLRPGDELLYITGKPYDTLEEIVGVR-GGeNAGSLKDFQIGYNAVDLTKdGKIDYDAVAAAINP--KT 167 Bacillus subtilis sub...
Q8Y7I1  84 SGTHAISTVLFGILRPDDELLYITGQPYDTLEEIVGMR-NQ-GQGSLKDFHIGYSSVPLLEnGDVDFPLIAEKMTR--KT 159 Listeria monocytogenes
Q9KAC8  91 SGTHAIATVLFGLLRPGDELLYITGKPYDTLEEVIGIR-GEeGGGSLKDFGITYHAVPLTAeQKVDKAAVKAAMNE--RT 167 Bacillus halodurans
Q5HPN4  84 SGTHAITLALQSTLKNNDELLYITGSPYDTLLEVIGIN-GN-GVESLKEYGVRYNEVELRD-GRIDIPKVITAIND--NT 158 Staphylococcus epider...
Q8EQP5  81 SGTHAITTALFGVLRPGDELVYITGKPYDTMEEVIGKP-GK-QEGSLHDFNIGYREIPLLAdGSVNYKQVKESWTS--NT 156 Oceanobacillus iheyensis
Q8DHD9 106 SGTHAIATALFGVLRPGDELISLAGPPYDTLEEVIGLR-GQ-GQGSLKDFGIHYRELPLLAsGEPDWGAIATCVQP--QT 181 Synechococcus elongatus
Q55407  83 SGTHAIACALYGILRPGDELLSAVGSPYDTLEEVIGLR-GS-CQGSLADFNISYRQLPLTAaGTVDWQGLETAVRP--ET 158 Synechocystis sp. PCC...
Q54763  83 SGTHAIAAALFGVLRPGDELLAIAGAPYDTLEEVIGTR-GE-GQGSLKDFGVSYRELALTEsGEVDWQALTTAIRP--NT 158 Synechococcus elongat...
Q8RA65  97 SGTHAISIVLFGNLKPNEELISASGKPYDTLEEVIGIK-GE-GRGSLRECGIIYKEVPLLEnGEMDVEGIKKAITs--KT 172 Caldanaerobacter subt...
3I16_A 178 TLVHIQRSTGYGWRRALLIEDIKSIVDCVKNIRKDIICFVDNCYGEFXDTKEPTDVGADLIAGSLIKNIGGGIAPTGGYL 257
P94479 168 KVIGIQRSKGYANRPSFLISEIKEMIRFVKEINENLIVFVDNCYGEFVEELEPCHVGADLMAGSLIKNPGGGLAKTGGYL 247 Bacillus subtilis sub...
Q8Y7I1 160 KMIGIQRSRGYADRPSFTIDKIKEMIIFVKNINPEVIVFVDNCYGEFAEYLEPTEVGADIIAGSLIKNPGGGLAKTGGYI 239 Listeria monocytogenes
Q9KAC8 168 KVIGIQRSKGYADRPSFSINEIEQMVQFVKGINPNVIVFVDNCYGEFVEAKEPCHVGVDVIAGSLIKNPGGGIVKTGGYV 247 Bacillus halodurans
Q5HPN4 159 KVVAIQRSKGYDQRPSITINEIEQAITSIKEVYPNIIIFVDNCYGEFVEDKEPIEVGADLIAGSLIKNPGGGLAKIGGYI 238 Staphylococcus epider...
Q8EQP5 157 KVIAIQRSKGYDERPSYTVDQISEMIQFVKGIDPSVIVFVDNCYGEFTETKEPLHVGADLMAGSLIKNPGGGLVRAGGYI 236 Oceanobacillus iheyensis
Q8DHD9 182 RMVLIQRSCGYTWRPSLSLEDIGKMIQLIKSQNPDVVCFVDNCYGEFVETQEPPHVGADLIAGSLIKNPGGTIATAGGYL 261 Synechococcus elongatus
Q55407 159 RLVLIQRSCGYSWRPSLAIADIARIIEIVKAQNPRTLCFVDNCYGEFIETVEPTAIGVDLMAGSLIKNPGGTIVTAGGYL 238 Synechocystis sp. PCC...
Q54763 159 RLALIQRSCGYSWRRSLSIDDIARIVALVKSQNPDTVCFVDNCYGEFIETREPTMVGADLMAGSLIKNPGGTIAPAGGYV 238 Synechococcus elongat...
Q8RA65 173 KMIMIQRSKGYDYRKSFTIAEIGEVIKEIRKVKEDIIVFVDNCYGEFTEKKEPTEVGADIVAGSLIKNIGGGIAPTGGYV 252 Caldanaerobacter subt...
3I16_A 258 AGTKDCIEKTSYRLTVPGIGGECGSTFGVVRSXYQGLFLAPHISXEALKGAILCSRIXELAGFEVXPKYDEKRSDIIQSI 337
P94479 248 VGKAKWIEACSYRMTSPGIGREAGASLYSLQEMYQGFFLAPHVVSQSLKGAVFTARFLEKLGFTSNPKWDAKRTDLIQSV 327 Bacillus subtilis sub...
Q8Y7I1 240 AGKEALIDLCGYRLTTPGIGREAGASLYSLLEMYQGFFLAPHVTAQAIKGARFTAAMLAEFGVVADPTWDAPRTDLIQSI 319 Listeria monocytogenes
Q9KAC8 248 AGKAPYVKQASYRLAAPGIGTEGGATLYSLLEMFQGLFLAPHVVSQAVKGAHFTAAFLDELGMRTSPRYDEQRTDLIQSV 327 Bacillus halodurans
Q5HPN4 239 AGRQDLIERCGYRLTAPGIGKEAGASLNSLQEMYQGFFLAPHVVSQSLKGALFTSLLLEKINMKTSPKYNVYRTDLIQTV 318 Staphylococcus epider...
Q8EQP5 237 AGNKELIHLCANRLTAPGLGKETGASLGMLQEMYQGFFLAPHTVGEALKGAILTARFLELAGFNTSPSYLEKRTDLIQTV 316 Oceanobacillus iheyensis
Q8DHD9 262 AGRADLIEQASYRLTAPGIGHEGGATFDQHRLLFQGLFLAPQMVGEALKCAHLLAYVFDELGYPVNPAPLSRRRDVIQAV 341 Synechococcus elongatus
Q55407 239 AGKEEWVEAGAYRLTAPGIGREGGATFDQNRLLFQGLFLAPQMVGEAMKCNHLLAHVFDQLGYPVNPAPLSPRRDVIQAI 318 Synechocystis sp. PCC...
Q54763 239 AGRADLVEAAACRLTAPGIGSSGGATFDQNRLLFQGLFLAPQMVAEAMKGSHLIAWVCDRLGYPVQPDPWEPRRDVIQAV 318 Synechococcus elongat...
Q8RA65 253 VGKKELVENASYKLYAPGIGKEVGPSLGFNRLILQGLFFAPKVVGEALKGAVLLSKVMSDLGYEVLPEYNEERTDIVQAV 332 Caldanaerobacter subt...
3I16_A 338 KFNDKDKLIEFCKGIQTGSPIDSFVSCEPWDXPGYTDQVIXAAGAFIQGSSIELSADAPIREPYIAYLQGGLTFDHAKIG 417
P94479 328 EFSDREKMIAFCQAIQFASPINAHVTPYPAYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKNA 407 Bacillus subtilis sub...
Q8Y7I1 320 SFHNKEKMVAFAQAIQAASPVNAHVLPIGAYMPGYEDDVIMAAGTFIQGASLELTADGPIREPYQLYVQGGLTYEHVKIA 399 Listeria monocytogenes
Q9KAC8 328 QFPDREKMIAFCQAIQAASPIDAHVTPQPSSMPGYEDPVIMAAGTFIQGASIELTADGPVRPPYIAYVQGGLTYEHVKLA 407 Bacillus halodurans
Q5HPN4 319 QFETKEQMISFCQSIQHASPINAHFSPEPSYMPGYEDDVIMAAGTFIQGSSIELSADGPIRPPYEAYVQGGLTYEHVKLA 398 Staphylococcus epider...
Q8EQP5 317 IFDEADQMIAFCQSIQENSPINSYVKPYPSDMPGYEDQVIMAAGTFIQGSSIELSADGPIRAPYTAYVQGGLTYTHVKIA 396 Oceanobacillus iheyensis
Q8DHD9 342 QLGSPEKLIAFCRILQRYSPVGSYLDPVPAPMPGYADDLVMAGGTFIDGSTSELSADGPLRPPYIVFCQGGTHHTHMALI 421 Synechococcus elongatus
Q55407 319 QLGSPEKLLAFCRALQGASPISSYLQPVPAAMPGYASEVVMAGGTFIDGSTSELSADGPLREPYTVFCQGGTHWTHMAIA 398 Synechocystis sp. PCC...
Q54763 319 RLGSAEKLVAFCRAIQQHSPIGAYLDPVPAPMPGYESDLVMAGGTFIDGSTSEFSADGPLREPYTVFCQGGSHHAQVAIA 398 Synechococcus elongat...
Q8RA65 333 KFRTEKELISFIQGIQLGSYVDAHVLPEPWDMPGYQDKVIMAAGGFIQGSSIELSADAPIREPYTAYVQGGLSYPQVKLA 412 Caldanaerobacter subt...
3I16_A 418 ILIALSRIV 426
P94479 408 ICSAVDSLM 416 Bacillus subtilis subsp. subtilis str. 168
Q8Y7I1 400 VTRAIQKTL 408 Listeria monocytogenes
Q9KAC8 408 VMQAADEML 416 Bacillus halodurans
Q5HPN4 399 VTRAVQHMq 407 Staphylococcus epidermidis RP62A
Q8EQP5 397 LLEAVKSLK 405 Oceanobacillus iheyensis
Q8DHD9 422 LEALLEAQV 430 Synechococcus elongatus
Q55407 399 LEEILAAFE 407 Synechocystis sp. PCC 6803
Q54763 399 LEAAIAAIG 407 Synechococcus elongatus PCC 7942
Q8RA65 413 ISIALSRIY 421 Caldanaerobacter subterraneus subsp. tengcongensis
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