6RIU


Conserved Protein Domain Family
ImpA_N

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pfam06812: ImpA_N 
ImpA, N-terminal, type VI secretion system
This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. The ImpA gene in Vibrio cholera and many other bacteria is expressed from the virulence factor operon which produces the pathogenic injection, type VI secretion system; although the exact function of this gene-product is not known it appears to be an essential component of the pathogenic effect.
Statistics
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PSSM-Id: 399652
Aligned: 127 rows
Threshold Bit Score: 43.3546
Threshold Setting Gi: 530328607
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6RIU_A             12 KPISSSNPVGERLVD-H----PLFDFIEDQMMKVg-----------------sLSHASVQWDEVEHSTLKLLGEQSKDIK 69 
WP_014257731        7 NPISDEHPSGEYLKDnR----TLYRTYRNAFNVAqssfrqlvetpdamqdavvVHTNAENWDALAKLCESCLSEQSKDVE 82  Vibrio fur...
Q7MDP8             16 LPISDEQPAGVDPRS-DitpqSLYYRLKDQRMQArnierna------iieeepILNYANLWQVFLDEVPQALASQTKDLE 88  Vibrio vul...
Q87HC9             14 APISEDNPTGIDPRE-DvspqSAYYRLKDQRMVArnaerna------iieeesIHTHNNLWRVFVEEVPEVLATQSKDFE 86  Vibrio par...
Q080V0             14 LPISIDAESGVDPRE-DisptSTYYLLKDVRNIArsrerka------ltdeedVLSVAVEWRPIFEQVPDILKQQSKDIE 86  Shewanella...
BAF88596           21 APIGDPPGCGTDPRA-DmsgnSPFLQMKDARADArrkeral-------dvdpdaPGAEDDWGSAGELGMQILSGVGKDLE 92  Azorhizobi...
QianUST:TMO_a0090  16 EPIAGARPAGEDPRE-DyrvdAPFRRLKDLRSAAraaeraa-------evedepQAPAEHWPEIDRLAADVLRHKAKDLE 87  Tistrella ...
Q28MX1             18 htaNNDGSVGENPRE-TdraiAEYRRLRDARSAAraeerkqe----taeardrALKVAPDWTIVRDLARFLLDEVGRDIE 92  Jannaschia...
vbi:Avi_6052        8 TALVENGPCGINIRV-DanyrEVYYRIKDARNQArteers--------ttpgeVIKVSQSWNLVSNLGLQITSSVSKDLE 78  Agrobacter...
WP_010973762        8 rdieflGNCGDNIRN-DsrtrEIYYRIKDERNQAraeera--------aspqdNLKISSSWDSVSNLGLQIIYSESKDVE 78  Agrobacterium
6RIU_A             70 LLVYLLQCLHNQVT-PTRLITSFAVMSEFLNQYWNDSYPAP---GARGNL----------PRRKFFSQM 124
WP_014257731       83 IYSWFTMAQLFSASpLESLAQALHTLEQMIEHFWDSLQPTLpenKRKADGdaeqrkevaeHRVKPLLQL 151 Vibrio furnissii
Q7MDP8             89 YVAWLIEALTRLDG-FKGMAVGYELATYYLENYWADLYPMP---DEDGLE----------TRISPIIGL 143 Vibrio vulnificus YJ016
Q87HC9             87 FVAWLIEALTRLYG-FRGMGVGYKIASAFVESYWDELHPMP---DEDGIE----------TRISAITGL 141 Vibrio parahaemolyticus
Q080V0             87 YVAWFIEAACRLYG-FKGLYFGFTLATELVERYWDTIYPTP---EPNDLA----------ERIAPLIGL 141 Shewanella frigidimar...
BAF88596           93 VAAWVIEALVRLDG-YRGLYTGCLLAEGLVRTFWDGIFPLP---DEDGND----------GRLSPFVAL 147 Azorhizobium caulinod...
QianUST:TMO_a0090  88 VAGLLIEAQVRLNG-FAGLAFGFDVATGLIRNFWDGLWPAP---DEDGIA----------SRVRPLMAL 142 Tistrella mobilis KA0...
Q28MX1             93 VAVWLIEAETRLDG-FDGLARAAEQLADMINAHGMALHPQP----EDALD----------RPFDMIAGL 146 Jannaschia sp. CCS1
vbi:Avi_6052       79 VLAWLAESRLRLEG-FPGLSEVYEATASLIERYSDELHSI----DDEDIE----------EKLAPFAGL 132 Agrobacterium vitis S4
WP_010973762       79 ILAWLAEASLRLRG-FHGLREIYELCGDLFYNHWDSLRSI----SDDNDE----------EKFAPFAGL 132 Agrobacterium
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