Conserved Protein Domain Family
ThrE

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pfam06738: ThrE 
Putative threonine/serine exporter
ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.
Statistics
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PSSM-Id: 399605
Aligned: 124 rows
Threshold Bit Score: 116.849
Threshold Setting Gi: 74509178
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAK41684 413 RYIMQLCRALMRYGAPTHRLEEYMQMTARVLEVEGQFLYLPGCMIMSFddp--------atrTAEvklVrVVQGVDLGRL 484  Aspergillus niger
Q8PCS6    20 aFVSEIAGRLHSYGTTAQRLEAAVIGLSQKLGLDCEPWSNPTGIILSFsdptksigssditrVIR---L-APGENDLYKL 95   Xanthomonas campes...
Q55DN3   509 PFLMELGRALTMSGVPSNRLEFELTLISTTFGIDGHFFTTPTGIFFSFgsphsil-spythfLRI-----NSTDYNMERM 582  Dictyostelium disc...
Q54Q20   524 PFLMELGRALLMSGVPAHRLEYELTLISGTFGIDGHFFTTPTGIFFSFgsphtil-spythfLRI-----NSTDYNMNRL 597  Dictyostelium disc...
Q09B83    19 AFILRLGKALHQYGTPAHRLEEQLRQVSERFGVEARFFSTPTSIFASFgtpel----lqtslIRV-----EPGEIDLERL 89   Stigmatella aurant...
Q1DBY8    22 AFTIRLGEALHRYGTPAHRLELLMQRVSERFGLEGRFFSTPTSIFSSFgppea----lrtslIRV-----EPGDMDLERL 92   Myxococcus xanthus...
Q15VY2    14 KFIVKLGIMLHKYGTPAFRLEAYLTELATYLGVRASFIATPTALTFVIwsdrre--deynhsVRV-----QPGDYDMNAL 86   Pseudoalteromonas ...
Q486V1    12 RFIIKLGKALHKLGSTAYRLEDNLLSIAKFLELRASFIITPTALTFILsddedd--qqynhlVRV-----SPGDIDLGSL 84   Colwellia psychrer...
Q088Q8    11 RFIIKLGKYLHKFGTPAYRLESHLQTVCNTLGIEGYFLISPTSMTFVLqhdteq---eynhvARV-----KPGDLDLGSL 82   Shewanella frigidi...
Q8EJZ8    11 KFIIKLGKALHKFGTPAYRLETHLQTVSRTLGIEGYFLISPTSMTFVLqhdtd----qeynhVAR---V-KPGELDLGSL 82   Shewanella oneidensis
CAK41684 485 AETHNVYKNVVHDmigvEEAIQELDLIMKRPPRFNKWILVVTYGLASVAVGPFAfDARPIDMPIIFFLGCLVGFMQHVLa 564  Aspergillus niger
Q8PCS6    96 SVADYVADSVASGrmsiAQGHTALRRLDRETDRRGKALQVLAFGLAAAGVAGLW-KLPWLDIATAGVIGMSIGLLTQYT- 173  Xanthomonas campes...
Q55DN3   583 VRLERLADKVIYGevscVEALEKLRKILAKKPLYNIYLTTFSYIMSSFTIAFFF-DVGWVEVGACSIIGFYVGLLCLLS- 660  Dictyostelium disc...
Q54Q20   598 ILLEQLADQVIYGhvscAEGLVRLKEILRLKPLYNNYLTVISFVLSSFAIAFFF-KAGWVEVGACSFVGLYVGLLSAVS- 675  Dictyostelium disc...
Q09B83    90 TLLDALTYEVIHDklspELGTQRVEAILQAPPRYGLLVTLLCWTLAAGAAARLF-GGGPREMCVAGLSSLSIGVLDQVL- 167  Stigmatella aurant...
Q1DBY8    93 TLLDTLADDVIHGqvppTEGAQRVDAILAQPERFGPALQLLCWTLAGGAAGRLF-GGGLKEMAVAAFSSLLIGTLNVLT- 170  Myxococcus xanthus...
Q15VY2    87 SRTDELATRLLAGevglEEADHQLDVINEMPSPYGKILTGLGFCAAPGAFAMLM-GASWQEILWTSLIGLVVYFLVLWS- 164  Pseudoalteromonas ...
Q486V1    85 ARIDELVDELIDGqrtlEEAIERLAEVKNKPAPYGTLLSFLAFGASSGAFAMLM-HTSWHDVFWSTILGWVTFAFVLWS- 162  Colwellia psychrer...
Q088Q8    83 ARTFELVEELSSGqrtlQEALERLEEIANKPNPYGHKLTLLAFGSSAGAFAMLM-GTGWHDVFWSAIFGLLVYSLVFWA- 160  Shewanella frigidi...
Q8EJZ8    83 ARTDELVDELTSGkrtlTEALDRLEEIANKPNPYGPVLTCFSFGTSAAAFAMLM-GTGWNDVFWSGLLGLLVYGFVYRA- 160  Shewanella oneidensis
CAK41684 565 PRSVLYSNVFEVTAAILTSFLARAFGSiyatvdgtherlfcfSALAQSSIALILPGFMVLCSSLELQSHQMIAGSIRMVY 644  Aspergillus niger
Q8PCS6   174 DKRPATKEAGEALAGLLAGVVAALVASlvgp--------lnlNTVIIASLVVLLPGMSLTNAFNELASQHWVSGTARLAG 245  Xanthomonas campes...
Q55DN3   661 SKVSLVGRVLEALSSCGGAIIASLFNCyisp--------ipiFTVTLGGIISLLPGLGLTLAVAEISTRNLVSGTSRLVG 732  Dictyostelium disc...
Q54Q20   676 SKYATVGRVLEALSACGGAVLASLFNAfiyp--------vhiFMVTLGGIIALAPGLSLTLAVAEISTRNLISGNARLVG 747  Dictyostelium disc...
Q09B83   168 RRGSRAARVLESAAALLSSVLAVAAASifgp--------lsvQVATLSGLIVLLPGLGLTVAINELATRNLISGTSRLTG 239  Stigmatella aurant...
Q1DBY8   171 RKQPSTARVLEPVAAILSSAVAALAASlmgp--------lsaQVATLAGLIVLLPGLSLTVAINELATRNLISGTSRLTA 242  Myxococcus xanthus...
Q15VY2   165 QISRRVTLMLEPAASLTAGLIACAISFyfdh-------gmniPLVVLSSVIILVPGLALTMGLAELSSRNLVSGTARVMD 237  Pseudoalteromonas ...
Q486V1   163 ERSRRMSDLLEPMAALTASLLASAISMidps--------iniPMVILSSIIVFIPGLSLTVGLSELAARHLMSGTARIMD 234  Colwellia psychrer...
Q088Q8   161 ERSKRIAEMLEPMAAVVCAILASGIAQldps--------inlPVTILSGIIIFVPGLALTLGLAELAARDLISGTARIMD 232  Shewanella frigidi...
Q8EJZ8   161 ERSSRMAEVLEPFATIVCAIVACAIARidpn--------iniPVVILSSIIIFIPGLALTLGLAELAARDLISGTARIMD 232  Shewanella oneidensis
CAK41684 645 SIIYSMFLGYGITVGTTIY 663  Aspergillus niger
Q8PCS6   246 AVTTVLKLTVGAVIAVTLt 264  Xanthomonas campestris pv. campestris
Q55DN3   733 VFSCLLQLTFGIALGTKFS 751  Dictyostelium discoideum AX4
Q54Q20   748 VFSCLLQLTFGIALGTRIS 766  Dictyostelium discoideum AX4
Q09B83   240 AVLVFLQLTFGVALGgrla 258  Stigmatella aurantiaca DW4/3-1
Q1DBY8   243 AALVFLQLGFGVALGsrls 261  Myxococcus xanthus DK 1622
Q15VY2   238 AVMQLFKLYFGAFLGISIG 256  Pseudoalteromonas atlantica T6c
Q486V1   235 SIMVLFKLYFGAVLGMALG 253  Colwellia psychrerythraea 34H
Q088Q8   233 AVMQLFKLYFGAVLGMTIG 251  Shewanella frigidimarina NCIMB 400
Q8EJZ8   233 ASMLLFKLYFGAVLGMAIg 251  Shewanella oneidensis
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