Conserved Protein Domain Family
DUF1180

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pfam06679: DUF1180 
Protein of unknown function (DUF1180)
This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown.
Statistics
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PSSM-Id: 369034
View PSSM: pfam06679
Aligned: 11 rows
Threshold Bit Score: 113.07
Threshold Setting Gi: 329664066
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001193113         10 LSRALASALLLs-----------LLLPElsgps-agrpPAARAAPDLQPAARGPRTR------------PPPPP------ 59  cattle
Q5FVQ7               10 PCHFLASAFVL------------LLLPAlnqsv-vlpsTVPRAVQESKPLEPGPRTL------------SPLPP------ 58  Norway rat
XP_003479489         10 LRNLLASALLL-------------LLPAlsrp--vavlRAAEASPGLGPLASGPRTL------------PPLSP------ 56  domestic...
Q8TBP5               10 LSHLLASVLLL------------LLLPElsgpl-avllQAAEAAPGLGPPDPRPRTL------------PPLPP------ 58  human
XP_851027            10 VSPLLAAALLLl-----------LLLPPpppgpggawaSLLRAA---APGPAAPGTS------------PPLRP------ 57  dog
XP_016286766         12 CRRFLSAALLLalsgqlssllllLLLRDg---------AASDISRPLSPEASLPPSR------------PPLPPla--sg 68  gray sho...
WGS:AANI:GJ18424-PA   7 NWHLLALVLLLt-----------LFL------------SHHDQSDAAAPNATSTNANtdprrtvkkdqaPPLPPaqdtav 63  Drosophi...
XP_006010435          9 sSCSLAWGLLIp-----------LLLS-----------AAAGLSSTLPPAQKMDSSN------------RPSPP------ 48  coelacanth
XP_015221295          9 FRASLFVCILLp-----------VLL-------------------------------------------PPV-------- 26  spotted gar
Q1RMK9                7 PARLLPLLLLL------------ALLGA----------PAARASRAQSAAPPQPGAErqp-------rpPPGPG------ 51  cattle
XP_003753342          6 PPPPLPLLLLLl-----------VLLAA----------PAVLARRAESASASQPEADhq---------sPPS-------- 47  Norway rat
NP_001193113         60 GSSAARP--AGRAPAlEAAGARGAEGGNGST------PGAGPAaddpggkagaggpAGGVLAVSP------------DPG 119 cattle
Q5FVQ7               59 GPTAAQP--RGQAQS-EGAGPRGAESRNGSI------PGAASEadgpeg-kagessLGGSLAVSP------------NPS 116 Norway rat
XP_003479489         57 GPTAAQS--PGRAPA-ESPVLRGPEGGNGSS------PGAGLSaddlsg-kageasLGGSLAVSP------------NPG 114 domestic...
Q8TBP5               59 GPTPAQQ--PGRGLA-EAAGPRGSEGGNGSN------PVAGLEtddhgg-kagegsVGGGLAVSP------------NPG 116 human
XP_851027            58 GPTAAGS--PGRAPA-DAAGPRGAEGGNGSS------PRAGLAaddsggkareedsAGGSLAVSP------------NPG 116 dog
XP_016286766         69 SATAAGSglPGSSRT-EFPSGQAGLSGNGSS------PGAGPAe-----------vGGGGLSVSP------------SPR 118 gray sho...
WGS:AANI:GJ18424-PA  64 QQTSAESsvPEKVVViSEKSQQAAAQHEHPT------------------------------GVLPeedvhiehsnmnDNT 113 Drosophi...
XP_006010435         49 -PVSG----PGNASTkPALHPNSNNHNNNNSnkpmndTRAGSG-------------GGGNLASVPgi---------pGSP 101 coelacanth
XP_015221295         27 -ATVG----PYKAPStKIQVGISQNTGNASSgntkmnTHTGSVgvregknnstgdfQSTSRTVAAel---------aAND 92  spotted gar
Q1RMK9               52 ---------PGNATGtGSGEAAGGGGSSNSS----------------------------GDALVTri---------sSLL 85  cattle
XP_003753342         48 ---------PGNATQlGSG--MAGGGGSNSS----------------------------VDAVVTri---------sSLL 79  Norway rat
NP_001193113        120 DKPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEEDDNTLFDANHPR 192 cattle
Q5FVQ7              117 DKPMT-QRALTVLVVVSAAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPR 189 Norway rat
XP_003479489        115 DKPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEEDDNTLFDANHPR 187 domestic...
Q8TBP5              117 DKPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPR 189 human
XP_851027           117 DKPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPR 189 dog
XP_016286766        119 DKPMT-QRALLVLMVVSAAVLVYFVIRTIRMRRRNRKTRRYGVLDTNLENMELTPL-----EQD-DDDDDTTLFDANHPR 191 gray sho...
WGS:AANI:GJ18424-PA 114 DFPDTyAAVFYILVGITSSAILVLVVRVYRL-RLSRAERKYGV-QGDRANQELTPLpmaieDVNsDEEEDHTLFEVN--- 188 Drosophi...
XP_006010435        102 ERPMT-QRALCVLVIVSAAVIVYFVIRTVRMRRKNRKTRRYGVLDTNIENMELTPL-----EQE-DDDDDNTLFDANHAR 174 coelacanth
XP_015221295         93 SRPMSiQRALYVLVAVSALVIVYFVIRTVKM-KKNRKTRRYGVLDTNLA-MEMTPL-----EQDeDEDDDTTLFDARISR 165 spotted gar
Q1RMK9               86 RDLHTlKAAVIVACAFTAFLIACLLLRVFRSGKRLKKTRKYDIITTPAERVEMAPL-----NEEdDEDEDSTVFDIK--- 157 cattle
XP_003753342         80 RDLPTlKATVIVACAFSALLIACLLLRVFRLGKRLKKTRKYDIITTPAERVEMAPL-----NEDeDEDEESAVFDIR--- 151 Norway rat
NP_001193113        193 R 193 cattle
Q5FVQ7              190 R 190 Norway rat
XP_003479489        188 R 188 domestic guinea pig
Q8TBP5              190 R 190 human
XP_851027           190 R 190 dog
XP_016286766        192 R 192 gray short-tailed opossum
WGS:AANI:GJ18424-PA 189 R 189 Drosophila virilis
XP_006010435        175 R 175 coelacanth
XP_015221295        166 R 166 spotted gar
Q1RMK9              158 Y 158 cattle
XP_003753342        152 Y 152 Norway rat
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