Conserved Protein Domain Family
DUF1176

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pfam06674: DUF1176 
Protein of unknown function (DUF1176)
This family consists of several hypothetical bacterial proteins of around 340 residues in length. Members of this family contain six highly conserved cysteine residues. The function of this family is unknown.
Statistics
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PSSM-Id: 429064
Aligned: 24 rows
Threshold Bit Score: 284.665
Threshold Setting Gi: 501039738
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015698193     26 QAIYNDWQVSCDNLNHCAARNSQDGQ---EL---VMKITREAGPEGKSSVSIDYQRNSDEqmadAPVANRLQMNGKTLsf 99  Rahnella aqu...
WP_013268551     46 ERTFRDWYAVCDNANGCYAFGRASEG---VG---WVRIAIAAGPDAQPGVVVGFWPENGS----FGGPLTARVDGTDL-- 113 Brevundimona...
jgi:Msil_0781    38 LKQFKDWTVGCDNLRNCVALGLSSES---DMsgaYLKISRAGAADARPSLSVTLMAEPKS----KAPALRLQFDGAAAg- 109 Methylocella...
jgi:Pmen_3175    27 YREIKDWVVACDNLRGCQALSATEDY---GHtplRLELRRAAGAQAPLQLSLHYAGQTEY--------FPLLLDGEPLsa 95  Pseudomonas ...
WP_013789670     26 YSNLKDWLVACDNTRQCTALSNATEEdvqKLptwSLSVSREAGPEGALHVGLFSYNKASG---------QPLLDGKPLqv 96  Pseudomonas ...
IEC:ABF-0014904  55 QKVFRHWQITCNNLNDCDIRN--------NDpylRVTLKREAGAQGKISLDFDLADKRQA----------LYLDGVRFpl 116 Dickeya dada...
P76559           25 QRAFSDWQVTCNNQNFCVARNTGDHN---GL---VMTLSRSAGAHTDAVLRIERGGLKSPeaseGEIAPRLLLDGEPLal 98  Escherichia ...
Q2YRN7           20 YKQIRDVSVLCDFAANCTLSLNPGTG---ENa-pGIGLYRSSKADSIPELRLSFSEQMPK-----TGKLEILVDGKPE-- 88  Brucella abo...
WP_012091683     30 FKKVRDTLVLCDFAQNCTLTLTPVAS---DGa-pGLGIFRSSQSGSKPLLRLSYVDPSQK-----TGKLEISIDGQTL-- 98  Brucella/Och...
WP_025293122     29 VQVFADWAVGCDNVRDCEAQALATEG---EEvpaFVTVSRRAGAGGQPTIAIPFAAGRRP--------IALLVDGKRWpq 97  Sphingomonas...
WP_015698193    100 nhrewdiskKHLS------------TTNRLVVNEFIAAIREGSSIQLAV-KADPAQsvr-pvISLKGIKAALLAIDAQQG 165 Rahnella aqu...
WP_013268551    114 ---------IAATdavgdeddypaaTVRADQVTRLIDAMGQGEAMTLAA-GTETVT------ISLSGAAASLLWIDERQG 177 Brevundimona...
jgi:Msil_0781   110 --------lPERPipvrqdgdsvsaPLPPEQVDAFLAALRTAKRLTVRLiDGKTLVdp--afVSLAGSAAALLYMDAQQN 179 Methylocella...
jgi:Pmen_3175    96 -------vaDALQlaqdd--delllSAEGAEAQALLAELRNGEQLRMAV-DGEDEAv-----VSLRGLSAALLLMDSVQG 160 Pseudomonas ...
WP_013789670     97 klqpgklteGSVPev---------ySIEGSDAQALIAELRNGQRLVLPT-EEGEAV------TSLSGMSAALLLMDSVQG 160 Pseudomonas ...
IEC:ABF-0014904 117 sqpawqtd--------eeegafyvhTDQLDVIQQFVMAAKNAKRLSLSE-HGGSQGnnqeesISLNGLNAALLLADERQG 187 Dickeya dada...
P76559           99 sgdkwrispWLLV------------TDDTATITAFLQMIQEGKAITLRD-GDQT--------ISLSGLKAALLFIDAQQK 157 Escherichia ...
Q2YRN7           89 ---------LDTNiaalkvrnnelvYVDEAGVAKLIGAMKNGQKLQLKL-ADKVSG------YSLSGFVGGLIYLDEQQA 152 Brucella abo...
WP_012091683     99 ---------LDVDvsalkaqddqldY--TGDVVKALDGMKNGQKLQLKF-AGKTST------YSLSGLVGGLIYVDEQQS 160 Brucella/Och...
WP_025293122     98 plri----------------eddqvRFGAVATDLLLPVLLKADRIELMD-VQGIVVg----rASLTGISAALKYTDEAQG 156 Sphingomonas...
WP_015698193    166 RVGTKTAWINRGVKPASTVPP-VPAMPVLPHFSEPHA----LSETEMSAITQna----atTIENNDCSLDPSEREVH--- 233 Rahnella aqu...
WP_013268551    178 RLGTSMALIRKGDRTASSVPA-GPTVPEVTPAPAVSQg--rYGDQEGQTLPAav----aaLPDVVQCRADTDFNPDLqaa 250 Brevundimona...
jgi:Msil_0781   180 RAGTVSALIDKGAAPSNAAAPeEPSIPAVKMTMDRTEpkrp---------------pgvaPATDESCKAYDPI------- 237 Methylocella...
jgi:Pmen_3175   161 RVDGVTALYRPGTRPASEVPV-APPAPRLRPYPGTAP----LAEAESRAIAEavmaatrsAWFEEEMNSTPEAE------ 229 Pseudomonas ...
WP_013789670    161 RLGTTTALLRKGNNPASSVPP-APAAPPVPTWQAPKP----LSEADSKRSLAavreamrsDWQPEMYEDELPEGQ----- 230 Pseudomonas ...
IEC:ABF-0014904 188 RLNNLSALLQVGNGEVAQVPP-VPVGQEINPAYTQPPp---LTNAKI--LINgvisakknLLEEEDCGLSKEARQLSe-- 259 Dickeya dada...
P76559          158 RVGSETAWIKKGDEPPLSVPP-APALKEVAVVNPTPTp---LSLEERNDLLDyg----nwRMNGLRCSLDPLRREVN--- 226 Escherichia ...
Q2YRN7          153 RDGTVAALQVKGTKP-------APAAPDITLIETVEQipegi--------------rkdfSDDAATCGGASPESFRLag- 210 Brucella abo...
WP_012091683    161 RDGTVEALQVKGSKP-------APVPPQLKLIETVEQipadi--------------rkdfSDEAAVCGGASPGTFRNag- 218 Brucella/Och...
WP_025293122    157 RTGTPTAIVDKGDRPAIEVPRrAMPAPIAIPVATRTAppdrLSAGSVRTLR-----------ETNACEAGPDAAPPEe-- 223 Sphingomonas...
WP_015698193    234 --IFALSNDKALMTVNCDMGA-YNLYALGFLVs---RQAPYKMENLALNmpf--klGEEDESPELINADFDPKTGMLSTY 305 Rahnella aqu...
WP_013268551    251 ivSAKLDANTVLWGVPCGAGA-YNFANAWFTT----RPDGSNPRRLTFP-------STGEPLDLLVNAAYDPATRVIDAF 318 Brevundimona...
jgi:Msil_0781   238 --VIRLSATETLWGI-CDQAAaYNFAYRFWIAgp-gRPKGASAAVFETPal----aAPDSDSSVVVNPSLSDNGLILSSN 309 Methylocella...
jgi:Pmen_3175   230 --AFALNEHEALVLIRTWCAA-YNCDFAVYRVs---RQPPYEERDLQLDplplehdGLSG------AVGYRPETGELAYL 297 Pseudomonas ...
WP_013789670    231 --AFALSDREALVILKTGCGA-YNCNYSLYQAp---FDQPQQARQASIPeipvfedLPPSG-----SVEFDPASGELSSF 299 Pseudomonas ...
IEC:ABF-0014904 260 --AEPLTNELALVMLNCGMGA-YQSSSMLFVTp---RNNPQAAQLLELPrpirpadSREEKIRWFTEADYDPESGMLYHS 333 Dickeya dada...
P76559          227 --VTALTDDKALMMISCEAGA-YNTIDLAWIVs---RKKPLASRPVRLRlpf--nnGQETNELELMNATFDEKSRELVTL 298 Escherichia ...
Q2YRN7          211 gfVTKIADGLNLVGLPCGAPGaYNQPYVFY--------SRYENRIVPVSlpv-isdDGPTTTDSAWNIDWNNRTRTLTGF 281 Brucella abo...
WP_012091683    219 gfETKIADGLDLIGLPCGSPGaYNQPYAFY--------SRYENKTVPISlpt-isdDGPTVTDTAWNIDWTQKTLTLAAF 289 Brucella/Och...
WP_025293122    224 -sWFRIDERHTLLLLSCGGGA-NNRSALPFIVtnggRKKGLAADYARFDhpt--gyTAEHGQTLLPNPEWDKDAGTITSR 299 Sphingomonas...
WP_015698193    306 DKGRGIGDCGVSSRWVF----DGK-QFRLAAFASEPSCDGYSSGg--EWPVLWVTQ 354 Rahnella aquatilis
WP_013268551    319 DKGRGLGDCGTASSWTW----TDR-GFVLRSSTAMPDCYGVPSE---YWPTFWVTR 366 Brevundimonas subvibrioides
jgi:Msil_0781   310 NKGRGVGDCGESAGWAY----DGA-QFRLVSLQRMDECRGVAPD---DWPTLYRAR 357 Methylocella silvestris BL2
jgi:Pmen_3175   298 HKGRGLADCGGAGSWRF----DGE-RFQLASFSFLSRCAGGNPG---EWPELWRVV 345 Pseudomonas mendocina ymp
WP_013789670    300 TLAMGMGGCGITQRWRY----DGK-GFVPVHATMLGTCLGLDST---YWPVLWRTA 347 Pseudomonas fulva
IEC:ABF-0014904 334 AKGRGIADCGESAQWVF----DGK-TFQLVAYNYQPECNGGQPG---DWPSVWAMP 381 Dickeya dadantii 3937
P76559          299 AKGRGLSDCGIQARWRF----DGQ-RFRLVRYAAEPTCDNWHGPd--AWPTLWITR 347 Escherichia coli K-12
Q2YRN7          282 FKGRGIGDCGTYDVWKAvdsgEGRvSFVLKEERAKGDCDGNYAGgpqNWPASWPPK 337 Brucella abortus 2308
WP_012091683    290 FKGRGLGDCGIYDVWKAtdsgEGRvRFVLVQERSKGDCDGNYAGgpeKWPASWPVN 345 Brucella/Ochrobactrum group
WP_025293122    300 IVGSPSGDCGSSQRFAW----DGE-AFRLIEQRAMSTCRGSL-----QWIRVWTVP 345 Sphingomonas sanxanigenens
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