Conserved Protein Domain Family
Claudin_3

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pfam06653: Claudin_3 
Tight junction protein, Claudin-like
This is a family of probable membrane tight junction, Claudin-like, proteins.
Statistics
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PSSM-Id: 399563
View PSSM: pfam06653
Aligned: 24 rows
Threshold Bit Score: 66.2635
Threshold Setting Gi: 309365717
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAS00515        1 MIILrtntlqrsdeipflligeIKTLGVL--ISLCFLFHTYGLFSDCWIESESFilhgwydehgelyFIRFFDGIRPDNM 78   Caenorhabditi...
XP_002638159    1 MDWK------------------LYALGLM--LIISWAAQGVGLFTPHWMTNDGE-----------------SRGILPWHS 43   Caenorhabditi...
CAP20889        1 MVR-------------------KSHCGYGffLIIALLLTLASVFTPGWRSYKGN--------------GAPDIGLISRYC 47   Caenorhabditi...
XP_002644049    1 MCLSg-----------------LTQILYGliMTGSAILTAVALFTPGWNTIENNvkdv------tngGKPDWNGLMPWSC 57   Caenorhabditi...
CAR98800        1 MLYFlipipns-----qsrgapIIIIGYFf-VVGGWLLEIAALLLPDWIVFSDG---------------GPSYGILPYPS 59   Caenorhabditi...
CAP36984        1 MKWVt-----------------VETICLLfsVLIGFVLNVLAVFLPYWIVETNYni----------rALTYSVGIIPFHF 53   Caenorhabditi...
CAR98443        1 M--------------------------------------------------------------------------VPYPS 6    Caenorhabditi...
XP_002644028    1 ML--------------------LPYACVTalVFLSIIFSGISLFTYGWATIRPFnply-----plidDDEILLGLVPFDP 55   Caenorhabditi...
CAR98444        1 MTDVk-----------------IAFLGFL--VFNSLIFNILGIFTPNWTSNRTY--------------LELGSGLRlt-- 45   Caenorhabditi...
Q95XC2          1 MAD-------------------LKFLILGifISIGFVLNIVGVVAPCFMVEKATad----------sKQHKCHAVNPFSS 51   Caenorhabditi...
CAS00515       79 ----------------VCIMMYVSLALLLVVI--LSYCLIVNQIRKNYTLVRTRRLLFGISLGTILASGITSIAFYIFTG 140  Caenorhabditi...
XP_002638159   44 gdtg--------wikaATVELYIAFLAFIPAI--GCYMIAVREDFKTGYTIRACKYLLILALMVFISALFTSGAVTLIRT 113  Caenorhabditi...
CAP20889       48 -------------------------------------GNGVREVNQYDCKAYGRFQLPFEKATLAFMIIAIILEIVSLGL 90   Caenorhabditi...
XP_002644049   58 ishsqgstcsdwwaelPGWMRCVVICMILSLI--VQIVAIIYNLLTCLACCCKKYIIHPLTLFAVVSTILLLITVIVYAA 135  Caenorhabditi...
CAR98800       60 vfsnf------gwavaACWLMYIASALCFVIF--FFYIAFLHILKKHGFSLQLRKFYYTLSILSLINGALLFTSYMLFAI 131  Caenorhabditi...
CAP36984       54 ayeap-------fhiaTSVMMLTAFVLYVFLVgfLVFALISCLVQKYKLC---KTGYLLVGILSAIVAILQISSFIAMQI 123  Caenorhabditi...
CAR98443        7 qlts--------mfptLCILMYIALGLSMVSL--LCFMVAFLLVRKDDYSGKVKFLLHLIAGSSLLIVLLVVVTIALAGS 76   Caenorhabditi...
XP_002644028   56 dtpfg-------wlvaTCIFMYLNFACSILTF--LFCVIGAIIFILRGDSRYQKYIYVILCGSTFLTGLFGAVAFVIFVA 126  Caenorhabditi...
CAR98444       46 ---------------lASSFMLGTLALSSITV--VIFFYVYYQVKNNDYSSNLRKWFRIIDLASILAIILTVAAIIIIAT 108  Caenorhabditi...
Q95XC2         52 mgss---------ydfASFALYTTVVCQFMVAlmYGFIVYETKIKKRQYSKEILSLFYYFKWFFLLIVVLIALSFVLIAI 122  Caenorhabditi...
CAS00515      141 EVKRENVLQRPsv------enYLGYSAKSSLISAGLCVVIC---GFSIKLalqrcrldddylnlndAEEDsVeiptknti 211  Caenorhabditi...
XP_002638159  114 DFSVRERKY------------EIGYLPGFCLGSAILSLIVW---MISMYL----------------GKGFrCcnqt---p 159  Caenorhabditi...
CAP20889       91 YLQSTSYELLAn--------vYLGYSYWIAVIAAVFLLISC---SLSGTLigpte-----------------------nt 136  Caenorhabditi...
XP_002644049  136 NWSEFQNGFNTs--------sQLGYSFWLAVGALILSAADVilgALAVFL----------------GENC---------- 181  Caenorhabditi...
CAR98800      132 GIDSFARKYPHs---------sIGFAVYIDLISAMIYFISG---PLYIVF----------------ARRFcpm------- 176  Caenorhabditi...
CAP36984      124 GMKMYIASIYYqq-------pQLGGCVYLTLSSGILCLISV---LLAIIL----------------SKTKl--------- 168  Caenorhabditi...
CAR98443       77 NLAFNV---------------ALGYSVWFCVASAIISAANA---LISEYIv---------------GKKF---------- 113  Caenorhabditi...
XP_002644028  127 SYHEELENYFYgdvsfiqrraQLHYHIS---FESIISKSNF---AISTHY----------------HGTHsCrvhdnnhy 184  Caenorhabditi...
CAR98444      109 SNSDNLISTPQggp----dpiALGYSAWLCFISVILTVAIA---SISEYI----------------ASEE---------- 155  Caenorhabditi...
Q95XC2        123 KFQ---SRFNDnt-------vYLSYQSLLLITTIIVCSINI---ALSRRLvvqvarti-rqnsthtANPFnFdttsv-ys 187  Caenorhabditi...
CAS00515      212 qqkK 215  Caenorhabditis briggsae
XP_002638159  160 pidA 163  Caenorhabditis briggsae
CAP20889      137 ehlH 140  Caenorhabditis briggsae
XP_002644049  182 ---C 182  Caenorhabditis briggsae
CAR98800      177 -plF 179  Caenorhabditis briggsae
CAP36984      169 ---A 169  Caenorhabditis briggsae
CAR98443      114 ---D 114  Caenorhabditis briggsae
XP_002644028  185 ylvY 188  Caenorhabditis briggsae
CAR98444      156 ---C 156  Caenorhabditis briggsae
Q95XC2        188 iskN 191  Caenorhabditis elegans
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